Yintoni i-Ewing's Sarcoma?

Umxholo

• Zeziphi iimpawu okanye iimpawu ze-Ewing’s sarcoma?
• Yintoni ebangela i-Ewing’s sarcoma?
• Ngubani osemngciphekweni we-Ewing's sarcoma?
• Ixilongwa njani i-Ewing’s sarcoma?
• Ukujonga iimvavanyo
• Izinto eziphilayo
• Iindidi ze-Ewing's sarcoma
• Iphathwa njani i-Ewing’s sarcoma?
• Izinketho zonyango kwi-sarcoma ye-Ewing
• Izinketho zonyango lwe-swingoma ye-Ewing's sarcoma
• Yintoni imbonakalo yabantu abane-sarcoma ka-Ewing?

Ngaba oku kuqhelekile?

I-sarcoma ye-Ewing sisifo somhlaza esinqabileyo sethambo okanye izicubu ezithambileyo. Kwenzeka ikakhulu kubantu abancinci.

Ngokubanzi, ichaphazela abantu baseMelika. Kodwa kulutsha oluneminyaka eli-10 ukuya kweli-19 ubudala, oku kuya kuma malunga nabantu baseMelika kweli qela leminyaka.

Oku kuthetha ukuba malunga ne-200 yamatyala e-United States ngonyaka.

I-sarcoma ibizwa ngegama likagqirha waseMelika uJames Ewing, owaqala wachaza ithumba ngo-1921. Akucaci ukuba yintoni ebangela i-Ewing's, ngoko ke akukho ndlela zaziwayo zokuthintela. Le meko iyanyangeka, kwaye, ukuba ubanjwe kwangethuba, unokuchacha ngokupheleleyo.

Qhubeka ufunda ukuze ufunde ngakumbi.

Zeziphi iimpawu okanye iimpawu ze-Ewing’s sarcoma?

Olona phawu luqhelekileyo lwe-Ewing's sarcoma yintlungu okanye ukudumba kwindawo yethumba.

Abanye abantu banokuvelisa isigaxa esibonakalayo kulusu lwabo. Indawo echaphazelekayo inokuba shushu ukufudumala ngaphandle kwebala.

Ezinye iimpawu zibandakanya:

• Ukuphelelwa ngumdla wokutya
• ifiva
• ukuhla ukusinda
• ukudinwa
• Ukuziva ungaphilanga ngokubanzi (malaise)
• ithambo eliphuka ngaphandle kwesizathu esaziwayo
• ianemia

Izidumba zihlala ezingalweni, emilenzeni, kwi-pelvis, okanye esifubeni. Kunokubakho iimpawu ezithile kwindawo yendawo. Umzekelo, unokufumana ukuphefumla okufutshane ukuba ithumba likho esifubeni sakho.

Yintoni ebangela i-Ewing’s sarcoma?

Oyena nobangela we-Ewing's sarcoma akucaci. Ayizuzwa njengelifa, kodwa inokunxulumana notshintsho olungelulo kwilifa elithile elenzeka ngexesha lokuphila komntu. Xa i-chromosomes 11 kunye ne-12 itshintshiselana ngezinto zemfuza, iyenza isebenze ngaphezulu kweeseli. Oku kunokukhokelela kuphuhliso lwe-Ewing's sarcoma.

ukumisela uhlobo oluthile lweseli apho i-Ewing's sarcoma ivela khona iyaqhubeka.

Ngubani osemngciphekweni we-Ewing's sarcoma?

Nangona i-swingoma ye-Ewing inokukhula nangaliphi na ixesha, ngaphezu kwabantu abanesifo bafunyaniswa ebusheni. Ixesha eliphakathi labo bachaphazelekayo.

E-United States, i-Ewing’s sarcoma kunokwenzeka ukuba ikhule eCaucasians kunaseAfrika-eMerika. IAmerican Cancer Society inika ingxelo yokuba umhlaza kunqabile ukuba uchaphazele amaqela eentlanga.

Amadoda anokubakho ngakumbi ekuphuhliseni imeko. Kuhlolisiso lwabantu abayi-1,426 abachaphazelekayo yi-Ewing's, babengamadoda kwaye besetyhini.

Ixilongwa njani i-Ewing’s sarcoma?

Ukuba wena okanye umntwana wakho unempawu, jonga ugqirha wakho. Malunga namatyala, esi sifo sele sisasazekile, okanye sisasazwa ngemetastasized, ngexesha lokuxilongwa. Ngokukhawuleza ukuxilongwa kwenziwa, unyango olusebenzayo lunokuba.

Ugqirha wakho uya kusebenzisa indibaniselwano yezi mvavanyo zilandelayo zokuqonda isifo.

Ukujonga iimvavanyo

Oku kunokubandakanya enye okanye ezingaphezulu kwezi zilandelayo:

• I-X-ray ukufanisa amathambo akho kunye nokuchonga ubukho besisu
• Ukuskena iMRI ukwenza umfanekiso wethishu ethambileyo, amalungu, izihlunu, kunye nolunye ulwakhiwo kwaye ubonise iinkcukacha zethumba okanye ezinye izinto ezingaqhelekanga
• Ukuskena kwe-CT kumfanekiso wokuwela kwamathambo kunye nezicubu
• Ukucingelwa kwe-EOS ukubonisa ukuhlangana kwamalungu kunye nezihlunu ngelixa umile
• Ukuskena kwethambo kuwo wonke umzimba wakho ukubonisa ukuba ithumba linemetastasized
• Ukuskena i-PET ukubonisa ukuba ngaba naziphi na iindawo ezingaqhelekanga ezibonwe kolunye ulusu zizidumba

Izinto eziphilayo

Emva kokuba i-tumor iboniswe, ugqirha wakho unokuyalela i-biopsy ukuba ijonge isiqwenga se-tumor phantsi kwe-microscope ukuchonga okuthe ngqo.

Ukuba ithumba lincinci, ugqirha wakho wotyando angayisusa yonke loo nto njengenxalenye ye-biopsy. Oku kubizwa ngokuba yi-excisional biopsy, kwaye yenziwa phantsi kwe-anesthesia ngokubanzi.

Ukuba ithumba likhulu, ugqirha wakho wotyando usenokulinqunqa. Oku kunokwenziwa ngokusika isikhumba sakho ukuze ususe isiqwenga sethumba. Okanye ugqirha wakho unokufaka inaliti enkulu engenanto kulusu lwakho ukuze ususe isiqwenga sethumba. Ezi zibizwa ngokuba yi-incisional biopsies kwaye zihlala zenziwa phantsi kwe-anesthesia ngokubanzi.

Ugqirha wakho ugqirha unokufaka inaliti ethanjeni ukuze athathe isampulu yolwelo kunye neeseli ukuze abone ukuba umhlaza usasazekile na kumongo wakho.

Nje ukuba isicu sethumba sisuswe, kukho iimvavanyo ezininzi ezinceda ekuchongeni i-sarcoma ye-Ewing. Uvavanyo lwegazi lunokufaka negalelo kulwazi kunyango.

Iindidi ze-Ewing's sarcoma

I-sarcoma ye-Ewing yahlulwe ngokokuba umhlaza usasazekile ukusuka ethanjeni okanye kwithishu ethambileyo eyaqala kuyo. Zintathu iintlobo:

• Indawo ye-Ewing's sarcoma: Umhlaza awusasazekanga kwezinye iindawo zomzimba.
• I-sarcoma yeMetastatic Ewing: Umhlaza unwenwele emiphungeni okanye kwezinye iindawo emzimbeni.
• Ukuphinda sarcoma kwe-Ewing: Umhlaza awuphenduli kunyango okanye ubuye emva kwekhosi eyimpumelelo yonyango. Ihlala iphinda ibuye emiphungeni.

Iphathwa njani i-Ewing’s sarcoma?

Unyango lwe-Ewing's sarcoma luxhomekeke ekubeni livela phi eli thumba, ubungakanani besisu, nokuba umhlaza usasazekile na.

Ngokwesiqhelo, unyango lubandakanya indlela enye okanye ezingaphezulu, kubandakanya:

• ichemotherapy
• unyango lwemitha
• utyando
• Unyango lweproton
• I-chemotherapy yedosi ephezulu edityaniswe nokufakelwa kweseli ye-stem

Izinketho zonyango kwi-sarcoma ye-Ewing

Indlela eqhelekileyo yomhlaza ongasasazekanga yindibaniselwano:

• utyando lokususa ithumba
• imitha kwindawo yethumba ukubulala nayiphi na iseli yomhlaza eseleyo
• ichemotherapy ukubulala iiseli ezinomdlavuza esele zisasazekile, okanye ii-micrometastasies

Abaphandi kolunye uphononongo luka-2004 bafumanise ukuba unyango oluhlangeneyo olunje luyimpumelelo. Bafumanise ukuba unyango lubangele ukuba kubekho iminyaka emi-5 yokuphila malunga neepesenti ezingama-89 kunye neminyaka engama-8 yokuphila malunga neepesenti ezingama-82.

Kuxhomekeka kwindawo yethumba, olunye unyango lunokufuneka emva kotyando ukubuyisela okanye ukubuyisela ukusebenza kwamalungu.

Izinketho zonyango lwe-swingoma ye-Ewing's sarcoma

Unyango lwe-Ewing's sarcoma oluye lwasasazeka kwisiza sokuqala luyafana nolo lwezifo zalapha, kodwa ngenqanaba elisezantsi lokuphumelela. Abaphandi kwelinye babika ukuba iminyaka emi-5 yokusinda emva konyango lwe-swingoma ye-Ewing's sarcoma yayimalunga neepesenti ezingama-70.

Akukho lonyango luqhelekileyo lwe-swingoma ye-Ewing ephindaphindayo. Ukhetho lonyango luyahluka ngokuxhomekeka ekubeni umhlaza ubuyile kwaye lwalunjani unyango lwangaphambili.

Uvavanyo oluninzi lweklinikhi kunye nezifundo zophando ziyaqhubeka ukuphucula unyango lwe-sarcoma ye-Ewing's metastasised and recurrent. Oku kubandakanya:

• Ukutshintsha kweseli
• Unyango lokuzikhusela
• unyango ekujoliswe kulo kunye nee-antibodies ze-monoclonal
• indibaniselwano entsha yamachiza

Yintoni imbonakalo yabantu abane-sarcoma ka-Ewing?

Njengoko unyango olutsha lukhula, imbonakalo yabantu abachaphazelekayo yi-Ewing's sarcoma iyaqhubeka ukuphucula. Ugqirha wakho ngowona mthombo wakho wolwazi malunga nembono yakho kunye nexesha lokuphila.

Umbutho waseMelika woMhlaza uxela ukuba iminyaka emi-5 yokusinda kwabantu abaye bafumana amathumba alapha malunga neepesenti ezingama-70.

Kulabo abanezicubu zemastastised, i-5 yeminyaka yokusinda iipesenti ezili-15 ukuya kuma-30. Imbonakalo yakho inokuba ntle ngakumbi ukuba umhlaza awusasazekanga nakwamanye amalungu ngaphandle kwemiphunga.

Inqanaba lokusinda kweminyaka emi-5 yabantu abane-sarcoma ephindaphindayo ka-Ewing.

Kukho ezinokuchaphazela umbono wakho, kubandakanya:

• ubudala xa ufunyaniswe
• ubukhulu bethumba
• indawo yethumba
• ukuba ithumba lakho liphendula njani kwi-chemotherapy
• amanqanaba e-cholesterol egazini
• unyango lwangaphambili lomhlaza owahlukileyo
• isini

Unokulindela ukuba ubekwe esweni ngexesha nasemva konyango. Ugqirha wakho uya kuphindaphinda ukujonga ukuba umhlaza usasazekile na.

Abantu abane-sarcoma ka-Ewing banokuba semngciphekweni omkhulu wokukhulisa uhlobo lwesibini lomhlaza. IAmerican Cancer Society iqaphela ukuba njengoko abantu abatsha abaninzi abane-Ewing’s sarcoma bephila de babe badala, iziphumo zexesha elide kunyango lwabo lomhlaza zinokubonakala. Uphando kule ndawo luyaqhubeka.