Ungaluqonda njani uvavanyo lwe-TGO-AST: I-Aspartate Aminotransferase

Umxholo

• Ithetha ntoni i-AST ephezulu
• Isizathu Ritis
• Xa uviwo luyalelwe

Uvavanyo lwe-aspartate aminotransferase okanye i-oxalacetic transaminase (AST okanye i-TGO), luvavanyo lwegazi oluceliweyo ukuba luphande izilonda ezonakalisa ukusebenza okuqhelekileyo kwesibindi, njenge-hepatitis okanye i-cirrhosis, umzekelo.

I-Oxalacetic transaminase okanye i-aspartate aminotransferase yi-enzyme ekhoyo esibindini kwaye ihlala iphakanyisiwe xa ukwenzakala kwesibindi kunganyangeki, kuba ibekwe ngaphakathi ngaphakathi kwiseli yesibindi. Nangona kunjalo, le enzyme ikwanokubakho entliziyweni, kwaye inokusetyenziswa njengophawu lwentliziyo, olunokuthi lubonakalise infarction okanye ischemia.

Njengommakishi wesibindi, i-AST ihlala ilinganiswa kunye ne-ALT, njengoko inokuphakanyiswa kwezinye iimeko, ingachazwanga ngale njongo. O Ixabiso lesalathiso se-enzyme liphakathi kwe-5 kunye ne-40 U / L. yegazi, enokwahluka ngokwelabhoratri.

Ithetha ntoni i-AST ephezulu

Nangona uvavanyo lwe-AST / TGO lungacacanga ncam, ugqirha unokuyalela olu vavanyo kunye nezinye ezibonisa impilo yesibindi, njengokulinganisa i-gamma-glutamyltransferase (GGT), i-alkaline phosphatase (ALK) kwaye ikakhulu i-ALT / TGP. Funda ngakumbi malunga novavanyo lwe-ALT.

Ukonyuka kwe-AST, okanye i-TGO ephezulu, inokubonisa:

• Ukudumba ngamandla;
• Hepatitis wentsholongwane egazini;
• Hepatitis yotywala;
• Ukuqina kwesibindi;
• Ithumba esibindini;
• Umhlaza wesibindi sokuqala;
• Ingxaki enkulu;
• Ukusetyenziswa kweyeza elibangela ukonakala kwesibindi;
• Ukungoneli kwentliziyo;
• Ischemia;
• Isuntswana lomfanekiso
• Ukutsha;
• Hypoxia;
• Ukuvinjelwa kwemibhobho ye-bile, njenge-cholangitis, i-choledocholithiasis;
• Ukulimala kwemisipha kunye ne-hypothyroidism;
• Ukusetyenziswa kwamayeza anje ngeherparin therapy, salicylates, opiates, tetracycline, thoracic okanye isoniazid

Ixabiso elingaphezulu kwe-150 U / L ngokubanzi libonisa ukonakala kwesibindi nangaphezulu kwe-1000 U / L kunokubonisa i-hepatitis ebangelwe kukusetyenziswa kwamayeza, njengeparacetamol, okanye ischemic hepatitis, umzekelo. Kwelinye icala, ukwehla kwamaxabiso e-AST kunokubonisa ukusilela kwe-vitamin B6 kwimeko yabantu abafuna i-dialysis.

[Uvavanyo-uphononongo-tgo-tgp]

Isizathu Ritis

Isizathu se-Ritis sisetyenziswa kunyango ukuvavanya ubungakanani bomonakalo wesibindi kwaye ke ngaloo ndlela kusekwe olona nyango lulungileyo kule meko. Lo mlinganiselo uthathela ingqalelo amaxabiso e-AST kunye ne-ALT kwaye xa ungaphezulu kwe-1 ubonakalisa ukonzakala okungaphezulu, njenge-cirrhosis okanye umhlaza wesibindi, umzekelo. Xa ingaphantsi kwe-1 inokubonisa isigaba esibi se-hepatitis yentsholongwane, umzekelo.

Xa uviwo luyalelwe

Uvavanyo lwegazi lwe-TGO / AST lunoku-odolwa ngugqirha xa kukho imfuneko yokuvavanya impilo yesibindi, emva kokubona ukuba umntu utyebile, unamanqatha esibindini okanye ubonakalisa iimpawu ezinje ngombala wolusu omthubi, iintlungu icala lasekunene lesisu okanye kwimeko yendle yokukhanya kunye nomchamo omnyama.

Ezinye iimeko apho kunokuba luncedo ukuvavanya le enzyme emva kokusebenzisa amayeza anokonakalisa isibindi kunye nokuvavanya isibindi sabantu abatya iziselo ezinxilisayo.