Uvavanyo lweNqanaba leFerritin

Umxholo

• Yintoni iferritin?
• Injongo yovavanyo lweferritin
• Amanqanaba asezantsi e-ferritin
• Amanqanaba aphezulu e-ferritin
• Uvavanyo lweferritin lwenziwa njani?
• Ukuqonda iziphumo zovavanyo lwegazi zeferritin
• Oonobangela bamanqanaba asezantsi e-ferritin
• Oonobangela bamanqanaba aphezulu e-ferritin
• Iziphumo ebezingalindelekanga zovavanyo lwegazi lwe-ferritin

Sibandakanya iimveliso esicinga ukuba ziluncedo kubafundi bethu. Ukuba uthenga amakhonkco kweli phepha, sinokufumana ikhomishini encinci. Nantsi inkqubo yethu.

Yintoni uvavanyo lweferritin?

Umzimba wakho uxhomekeke kwisinyithi kwiiseli ezibomvu zegazi ukuhambisa ioksijini kuzo zonke iiseli zayo.

Ngaphandle kwentsimbi eyaneleyo, iiseli zakho ezibomvu azizukukwazi ukubonelela ngeoksijini eyaneleyo. Nangona kunjalo, i-iron eninzi ayilungelanga umzimba wakho. Zombini amanqanaba aphezulu kunye asezantsi e-iron anokubonisa ingxaki enkulu.

Ukuba ugqirha wakho ukrokrela ukuba unengxaki yokunqongophala kwe-iron okanye i-iron overload, banoku-odola uvavanyo lwe-ferritin. Oku kulinganisa isixa sesinyithi esigciniweyo emzimbeni wakho, esinokunika ugqirha wakho umfanekiso opheleleyo wamanqanaba akho esinyithi.

Yintoni iferritin?

IFerritin ayifani nqwa nentsimbi emzimbeni wakho. Endaweni yoko, i-ferritin yiprotein egcina isinyithi, iyikhuphe xa umzimba wakho uyifuna. UFerritin uhlala ehlala kwiiseli zomzimba wakho, encinci kakhulu ejikeleza egazini lakho.

Eyona ndawo kugxilwe kuyo kakhulu yi-ferritin zihlala kwiiseli zesibindi (ezaziwa ngokuba zii-hepatocytes) kunye namajoni omzimba (awaziwa njengeeseli ze-reticuloendothelial).

IFerritin igcinwa kwiiseli zomzimba de kube lixesha lokwenza iiseli ezibomvu zegazi. Umzimba uya kusayina iiseli ukuba zikhuphe i-ferritin. I-ferritin ibophelela kwenye into ebizwa ngokuba yi-transferrin.

I-Transferrin yiprotein edibanisa ne-ferritin ukuyisa apho kwenziwa khona iiseli ezibomvu zegazi. Khawufane ucinge ngokudluliselwa kwiteksi ezinikele yentsimbi.

Ngelixa kubalulekile ukuba umntu abe namanqanaba aqhelekileyo esinyithi, ukuba nentsimbi egciniweyo eyaneleyo kubalulekile. Ukuba umntu akanayo i-ferritin eyaneleyo, iivenkile zentsimbi zinokuphelisa ngokukhawuleza.

Injongo yovavanyo lweferritin

Ukwazi ukuba unayo i-ferritin eninzi egazini lakho okanye awonelanga kunganika ugqirha wakho izikhokelo malunga nenqanaba lakho le-iron. Okukhona i-ferritin isegazini, kokukhona isinyithi sigciniwe.

Amanqanaba asezantsi e-ferritin

Ugqirha wakho unokuyalela uvavanyo lwe-ferritin ukuba unezinye zeempawu ezilandelayo ezinxulumene namanqanaba asezantsi e-ferritin:

• Ukudinwa okungachazwanga
• isiyezi
• intloko engapheliyo
• ubuthathaka obungachazwanga
• kukhala ezindlebeni zakho
• ukucaphuka
• Iintlungu zomlenze
• ukuqhawukelwa ngumphefumlo

Amanqanaba aphezulu e-ferritin

Unokuba namanqanaba aphezulu kakhulu e-ferritin, anokubangela neempawu ezingathandekiyo. Iimpawu ze-ferritin engaphezulu zibandakanya:

• isisu esibuhlungu
• ukubetha kwentliziyo okanye iintlungu esifubeni
• ubuthathaka obungachazwanga
• intlungu edibeneyo
• Ukudinwa okungachazwanga

Amanqanaba e-Ferritin nawo anganyuka ngenxa yomonakalo kumalungu akho, anjengesibindi kunye ne-spleen.

Uvavanyo lunokusetyenziselwa ukubeka esweni impilo yakho iphela, ngakumbi ukuba unemeko enxulumene nentsimbi ebangela ukuba ube nentsimbi eninzi okanye encinci egazini lakho.

Uvavanyo lweferritin lwenziwa njani?

Uvavanyo lwe-ferritin lufuna kuphela inani elincinci legazi ukufumanisa amanqanaba akho e-ferritin ngokuchanekileyo.

Ngamanye amaxesha, ugqirha unokukucela ukuba ungatyi ubuncinci iiyure ezili-12 ngaphambi kokuba utsale igazi lakho. Ngokwe-American Association for Clinical Chemistry (AACC), uvavanyo luchanekile ngakumbi xa lwenziwa kusasa emva kokuba ungakhange utye ixeshana.

Ingcali yezempilo inokufaka ibhanti engalweni yakho ukwenza imithambo yakho ibonakale ngakumbi. Emva kokusula isikhumba sakho nge-swab ye-antiseptic, umboneleli ufaka inaliti encinci emthanjeni wakho ukuze ufumane isampuli. Isampulu ke ithunyelwa elebhu ukuyohlolwa.

Akufanelekanga ukuba uthathe naziphi na izilumkiso ezizodwa ngaphambi kokuba wenze uvavanyo lwegazi.

Iikiti zokuvavanya ekhaya ziyafumaneka. Ungathenga uvavanyo lweLetsGetChecks olujonga amanqanaba e-ferritin kwi-intanethi apha.

Ukuqonda iziphumo zovavanyo lwegazi zeferritin

Iziphumo zovavanyo lwegazi ze-ferritin zivavanywa kuqala ukubona ukuba amanqanaba akho aphakathi kwamanqanaba aqhelekileyo. NgokweKliniki yaseMayo, amabakala aqhelekileyo ngala:

• I-nanogram ezingama-20 ukuya kuma-500 ngeemililitha emadodeni
• Ama-nanograms angama-20 ukuya kuma-200 nge-milliliter kwabasetyhini

Qaphela ukuba ayizizo zonke iilebhu ezinesiphumo esifanayo kumanqanaba e-ferritin egazini. Le yimigangatho esemgangathweni, kodwa iilabhs ezahlukileyo zinokuba namaxabiso ahlukileyo. Soloko ubuza ugqirha wakho uluhlu oluqhelekileyo lwelebhu xa usenza isigqibo sokuba ngaba amanqanaba akho e-ferritin aqhelekile, aphezulu, okanye asezantsi.

Oonobangela bamanqanaba asezantsi e-ferritin

Inqanaba le-ferritin elisezantsi kuneliqhelekileyo linokubonisa ukuba unesiphene se-iron, esinokuthi senzeke xa ungasebenzisi i-iron eyaneleyo ekutyeni kwakho kwemihla ngemihla.

Enye imeko echaphazela amanqanaba esinyithi yi-anemia, kulapho ungenazo iiseli ezibomvu zegazi ngokwaneleyo ukuze isinyithi sincamathele kuso.

Imiqathango eyongezelelweyo ibandakanya:

• ukuphuma kwegazi okugqithisileyo
• iimeko zesisu ezichaphazela ukufakwa kwamathumbu
• ukopha ngaphakathi

Ukwazi ukuba amanqanaba akho e-ferritin asezantsi okanye aqhelekileyo anokunceda ugqirha wakho abone ngcono unobangela.

Umzekelo, umntu one-anemia uya kuba namanqanaba asezantsi egazi kunye ne-ferritin ephantsi.

Nangona kunjalo, umntu onesifo esinganyangekiyo unokuba namanqanaba asezantsi egazi, kodwa amanqanaba aqhelekileyo okanye aphezulu e-ferritin.

Oonobangela bamanqanaba aphezulu e-ferritin

Amanqanaba eFerritin aphezulu kakhulu anokubonisa iimeko ezithile.

Omnye umzekelo yi-hemochromatosis, kulapho umzimba wakho uthatha i-iron eninzi.

Ezinye iimeko ezibangela amanqanaba aphezulu e-iron aquka:

• irheumatoid Arthritis
• hyperthyroidism
• ukuqala kwabantu abadala Isifo se-Still
• uhlobo lwe-2 yeswekile
• Ileukemia
• I-lymphoma yeHodgkin
• ityhefu yentsimbi
• utofelo-gazi rhoqo
• isifo sesibindi, njenge-hepatitis C engapheliyo
• isifo somlenze esingazinzanga

UFerritin yinto eyaziwayo njenge-reactant phase acute. Oku kuthetha ukuba xa umzimba ufumana ukudumba, amanqanaba e-ferritin aya kunyuka. Kungenxa yoko le nto amanqanaba e-ferritin anokuphakama kubantu abanezifo zesibindi okanye iintlobo zomhlaza, ezinje ngeHodgkin's lymphoma.

Umzekelo, iiseli zesibindi zigcine i-ferritin. Xa isibindi somntu sonakele, i-ferritin ngaphakathi kweeseli iqala ukuphuma. Ugqirha angalindela phezulu kunamazinga aqhelekileyo e-ferritin kubantu abanezi kunye nezinye iimeko zokuvuvukala.

Oonobangela abaqhelekileyo bamanqanaba aphakamileyo e-ferritin kukutyeba, ukudumba, kunye nokusela utywala mihla le. Oonobangela abaqhelekileyo bamanqanaba aphakamileyo aphathelene ne-ferritin yimeko ye-hemochromatosis.

Ukuba iziphumo zovavanyo ze-ferritin ziphezulu, ugqirha wakho uya kuthi aodole ezinye iimvavanyo ezinokubonelela ngakumbi ngamanqanaba esinyithi emzimbeni wakho. Olu vavanyo lubandakanya:

• uvavanyo lwesinyithi, olinganisa ubungakanani bentsimbi ejikeleza emzimbeni wakho
• Uvavanyo lokuqina kwesinyithi (TIBC), olinganisa inani lokudluliselwa emzimbeni wakho

Iziphumo ebezingalindelekanga zovavanyo lwegazi lwe-ferritin

Uvavanyo lwegazi lwe-ferritin alunxulunyaniswa neziphumo ebezingalindelekanga ezimandundu kuba kufuna ukufumana isampulu yegazi. Thetha nomboneleli wakho, nangona kunjalo, ukuba unesifo sokopha okanye ukruneke ngokulula.

Unokulindela ukungonwabi xa igazi lakho litsalwa. Emva kovavanyo, iziphumo ebezingalindelekanga zibandakanya:

• ukopha kakhulu
• ndiziva ndityhafile okanye ndinentloko elula
• ukugruzuka
• usulelo

Soloko wazisa umboneleli wakho wezonyango ukuba ufumana ubunzima obubonakala buqhelekileyo.