yintoni, iimpawu, isifo kunye nonyango

Umxholo

• Iimpawu zosulelo ngu IFusarium spp.
• Isasazeka njani
• Uxilongo lwenziwa njani
• Unyango lweFusariosis

I-Fusariosis sisifo esosulelayo esibangelwa ngundo olungenelelayo, IFusarium spp., enokufumaneka kwindalo esingqongileyo, ikakhulu kumasimi. Usulelo kunye IFusarium spp. kuxhaphake kakhulu kubantu abanamajoni omzimba athomalalisiweyo, nokuba kungenxa yezifo zehematological okanye ngenxa yokufakelwa komongo wethambo, umzekelo, ukuba yinto exhaphakileyo kwezi meko ukusasazeka kwefusariosis, apho ukungunda kungafikelela kumalungu amabini nangaphezulu. , iyenza mandundu imeko yeklinikhi yomntu.

Ezona ntlobo ziphambili ze IFusarium ezinokubangela izifo ebantwini zezi IFusarium solani, IFusarium oxysporum, Iifusarium verticillioides kwaye IFusarium proliferatum, enokuchongwa kwiimvavanyo zaselebhu.

Iimpawu zosulelo ngu IFusarium spp.

Iimpawu zosulelo kwiFusarium spp. azicacanga ncam, kuba ziyafana neempawu zezinye izifo ezibangelwa ngumngundo, ixhomekeke kwinkqubo yomzimba yokuzikhusela, kuba iyifungi enomdla, kwaye inokwahluka ngokobume bomngundo emzimbeni. Iimpawu eziphambili kunye neempawu ze-fusariosis zezi:

• Ifiva;
• Ubuhlungu bemisipha;
• Izilonda zolusu, ezibuhlungu kwaye zinokukhula zibe zizilonda kwaye zibonakale rhoqo esiqwini nasemaphethelweni;
• Ukuhla kwamanqanaba okuqonda;
• Ukudumba kwenwebu;
• Ukutshintsha kombala, ubukhulu kunye nokumila kwesikhonkwane, ukongeza kubukho bolusu, kwezinye iimeko;
• Iingxaki zokuphefumla, zentliziyo, zesibindi, zezintso okanye zemithambo-luvo, kuxhomekeke kwindawo ekungunda kuyo.

Usulelo kunye IFusarium spp. Kuqhelekile ukuba kwenzeke kubantu abanezifo ze-hematological, i-neutropenia, abafumene ukufakelwa umongo wethambo okanye i-chemotherapy, abasebenzisa iiprophylactic antifungals ukuthintela usulelo ngo UCandida sp., umzekelo, kwaye unesifo esithintela amajoni omzimba.

Isasazeka njani

Usulelo kunye IFusarium spp. Kwenzeka ikakhulu ngokurhogela ii-spores ezikhoyo kwindalo esingqongileyo, kuba le fungus ifumaneka ikakhulu kwizityalo nasemhlabeni. Nangona kunjalo, usulelo lunokwenzeka ngokuchaphazela ngokuthe ngqo ukungunda, ikakhulu ngenxa yokusikwa okubangelwa lisebe, umzekelo, okukhokelela kwi-keratitis yefungal.

I-keratitis yefungal yenye yeempawu zeklinikhi yosulelo ngu IFusarium spp. kwaye iyahambelana nokudumba kwe-cornea enokubangela ubumfama, kwaye kubalulekile ukuba ichongwe kwaye inyangwe ngokufakelwa i-corneal ngokukhawuleza okukhulu ukuthintela ukusasazeka kwefungus. Ukongeza, ukungunda keratitis ngu IFusarium kungenzeka ngenxa yokusetyenziswa kweelensi zonxibelelwano ezingcoliswe yile fungus. Funda ngakumbi malunga ne-keratitis.

Uxilongo lwenziwa njani

Ukuchongwa kwe-fusariosis kwenziwa ngugqirha wesifo esosulelayo okanye ugqirha ngokubanzi ngokuvavanya iimpawu kunye neempawu ezibonisiweyo, ukongeza kwiziphumo zovavanyo lwaselebhu. Uvavanyo oluqinisekisa usulelo ngo IFusarium spp. Kukuzahlula komngundo kwiindawo ezosulelekileyo, ezinokuba sisikhumba, umphunga okanye igazi ngokwesigulana.

Emva kokuzahlula kunye nenkcubeko, ukubonwa kwemicroscopic kuyenziwa ukujonga ukungunda okunoxanduva losulelo. Nangona le iyindlela yokuqonda isifo eqinisekisa i-fusariosis, obu buchule buthatha ixesha, njengoko kuthatha ixesha ukuba ukungunda kukhule ngokwaneleyo ukuze kubonwe phantsi kwemicroscope. Ukongeza, ukubekwa wedwa kunye nokuqwalaselwa akuvumeli ukuchongwa kohlobo olunoxanduva losulelo, olufuna ukusetyenziswa kweendlela zeemolekyuli ukwenza ulwazelelo, olufuna ixesha.

Ubuchule be-immune bunokusetyenziselwa ukuchonga IFusarium spp., Kwaye ijolise ekuchongeni izinto zodonga lweseli yfungal, nangona kunjalo ezi ndlela zingacaciswanga ekuchongeni iFusarium spp, kuba icandelo elifunwayo liyinxalenye yesinye isikhunta, I-Aspergillus sp., umzekelo, enokudida ukuxilongwa.

Ngaphandle kokuhlukaniswa kunye nokuchongwa kwefungus kufuna ixesha elininzi, iimvavanyo zisakhonjisiwe ukuqinisekisa usulelo.Ukongeza, uvavanyo lwe-histological lunokwenziwa, apho kwenziwa khona i-biopsy yethishu kwaye, ukuba ubukho befungus buchongiwe, unyango lweprophylactic lunokuqaliswa ngelixa ulinde iziphumo zenkcubeko.

Unyango lweFusariosis

I-Fusariosis inyangwa ngee-antifungal agents ekufuneka zisetyenzisiwe ngokwengcebiso kagqirha, kunye ne-Amphotericin B kunye neVoriconazole yeyona nto ibonisiweyo. I-Amphotericin B yeyona nto iphambili ekubulaweni kwe-fusariosis, nangona kunjalo eli chiza linxulunyaniswa namanqanaba aphezulu etyhefu kwaye ezinye izigulana aziphenduli kunyango, kwaye nokusetyenziswa kweVoriconazole kuyacetyiswa.

O IFusarium spp. Inokuxhathisa okungaphakathi kwi-Fluconazole kunye ne-antifungals zodidi lwe-echinocandin, njenge Micafungin kunye neCaspofungin, eyenza unyango lube nzima kwaye inokunxulunyaniswa namazinga aphezulu okugula kunye nokufa.