Iiglucocorticoids

Umxholo

• Yintoni i-glucocorticoids?
• Uluhlu lweziyobisi zeglucocorticoid
• Yintoni unyango lwe-glucocorticoids?
• Ukuphazamiseka ngokuzenzekelayo
• Utywala kunye nesifuba
• Ukungabikho kwe-adrenal
• Ukumelwa yintliziyo
• Umhlaza
• Iimeko zesikhumba
• Ugqirha
• Imiphumela
• Thetha nogqirha wakho

Ushwankathelo

Iingxaki ezininzi zempilo zibandakanya ukudumba. IiGlucocorticoids ziyasebenza ekuyekiseni ukudumba okwenzakalisayo okubangelwa kukuphazamiseka kwenkqubo yomzimba yokuzikhusela. La machiza anokusetyenziswa okuninzi. Nangona kunjalo, ziza neziphumo ebezingalindelekanga. Oku kunokuba nzima, ngakumbi ukuba usebenzisa la mayeza ixesha elide.

Yintoni i-glucocorticoids?

Iziyobisi zeGlucocorticoid ziinguqulelo ezenziwe ngabantu zeglucocorticoids, ii-steroids ezenzeka ngokwendalo emzimbeni wakho. Banemisebenzi emininzi. Enye kukuphazamisa ukudumba ngokungena kwiiseli kunye nokucinezela iiproteni eziqhubela phambili ukukhuthaza ukudumba. Banceda umzimba wakho uphendule kuxinzelelo kwaye ulawule indlela umzimba wakho usebenzisa ngayo amafutha kunye neswekile.

Ngenxa yokuba i-glucocorticoids inemisebenzi emininzi, yenziwe ngumntu okanye i-glucocorticoids eyenziweyo iye yaphuhliswa ukunceda ukunyanga iimeko ezininzi ezahlukeneyo.

Uluhlu lweziyobisi zeglucocorticoid

Imizekelo yeziyobisi ze-glucocorticoid zibandakanya:

• beclomethasone
• yivsentsi
• mfumomfi
• icortisone
• dexamethasone
• hydrocortisone
• imethylprednisolone
• yingca
• ubume
• yesithathu

Yintoni unyango lwe-glucocorticoids?

I-synthetic glucocorticoids inokuba namandla ngakumbi kune-steroids eyenzeka ngokwendalo. Zisetyenziselwa ukunyanga iimeko ezininzi.

Ukuphazamiseka ngokuzenzekelayo

Izifo ezisebenza ngokuzenzekelayo zingabangela umonakalo omkhulu ekuvukeleni xa umzimba uhlasela ngempazamo. Izifo ezizimeleyo zibandakanya:

• isifo sokugubhuka
• irheumatoid Arthritis
• isifo sokudumba
• ukudumba okwenziwa sisilonda sikabhobhosi
• Psoriasis
• onokhwekhwe

I-Glucocorticoids inokunciphisa indlela iiseli zomzimba ezisebenza ngayo. Oku kunceda ukunciphisa ukonakaliswa kwangaphakathi kwezi zifo. Bacinezela ukudumba kukusabela okuzenzekelayo. Oku kunokunciphisa iintlungu, ukudumba, ukubamba, kunye nokurhawuzelela.

Utywala kunye nesifuba

I-Allergies kunye ne-asthma ziimeko apho amajoni akho omzimba aphendula kwizinto eziqhelekileyo ezingenabungozi. Kule meko, izinto ezinjenge-pollen okanye amandongomane zinokubangela ukuphendula ngokudlamkileyo. Iimpawu ziyahluka kwaye zibandakanya:

• ukurhawuzelela
• ukurhawuzelela, amehlo anamanzi
• intloko elula
• ubomvu, imihlathi, okanye ukukhawuleza
• Ukuthimla nokuxinana okanye impumlo ezihambisayo
• ukudumba kobuso bakho, imilebe, okanye umqala
• ingxaki yokuphefumla

I-Glucocorticoids inokunyanga oku kugqithisa ngokuyeka ukudumba kunye nokuthomalalisa ukusebenza kweeseli zomzimba.

Ukungabikho kwe-adrenal

Ukuba une-adrenal insufficiency, umzimba wakho awunako ukuvelisa i-cortisol eyaneleyo. Oku kunokuba sisiphumo semeko efana nesifo iAddison okanye ukususwa ngotyando kwamadlala akho eadrenal. I-Glucocorticoids inokusetyenziselwa ukubuyisela i-cortisol engenakwenziwa ngumzimba wakho.

Ukumelwa yintliziyo

Ukusetyenziswa kwexesha elifutshane (ngaphantsi kweentsuku ezisi-7) ze-glucocorticoids kunokunceda ukunyanga ukusilela kwentliziyo ngokwandisa amandla omzimba wakho wokuphendula kwezinye i-diuretics. Nangona kunjalo, oku akuyona into eqhelekileyo.

Umhlaza

I-Glucocorticoids ingasetyenziselwa unyango lomhlaza ukunciphisa ezinye zeziphumo ebezingalindelekanga zekhemotherapy. Zingasetyenziselwa ukubulala ezinye iiseli zomhlaza kwezinye iintlobo zomhlaza, kubandakanya:

• leukemia etsolo lymphoblastic
• wegazi lymphoblastic ezingapheliyo
• IHodgkin lymphoma
• I-non-Hodgkin lymphoma
• myeloma ezininzi

Iimeko zesikhumba

Iimeko zesikhumba ezisuka kwi-eczema ukuya kwi-poison ivy ziphathwa nge-glucocorticoids. Oku kubandakanya i-counter-counter-counter kunye ne-creams ye-topical oyisebenzisayo kulusu lwakho kunye neyeza ozithathayo ngomlomo.

Ugqirha

IiGlucocorticoids zinokusetyenziswa ngexesha le-neurosurgeries ezibuthathaka. Banciphisa ukuvuvukala kwizicubu ezinobuthathaka. Ziye zilawulwe kwangoko emva kokufakelwa komzimba ukuze kuthintelwe amajoni omzimba ekuchaseni ilungu lomnikeli.

Imiphumela

I-Glucocorticoids inokuvakala njengeziyobisi ezingummangaliso, kodwa zinemiphumo emibi. Ezinye zeziphumo ebezingalindelekanga zingonakalisa kakhulu. Kungenxa yoko le nto la machiza engamiselwanga ukusetyenziswa kwexesha elide.

La machiza anoku:

• yonyuse inqanaba leswekile yegazi, enokubangela iswekile okwethutyana kunye nexesha elide
• cinezela amandla omzimba wakho wokufunxa ikhalsiyam, enokukhokelela kwi-osteoporosis
• yandisa amanqanaba akho e-cholesterol kunye ne-triglyceride
• ukwandisa umngcipheko wezilonda kunye nesisu
• ukulibaziseka kokuphola kwenxeba, okufuna isixa esithile sokudumba
• cinezela amajoni akho omzimba kwaye ukwenze uthambekele ngakumbi kusulelo

Ukusetyenziswa kwexesha elide kwe-glucocorticoids kunokubangela ukulahleka kwezicubu zomzimba. Inokubangela nesifo sikaCushing's, esinokukhokelela ku:

• inqatha elinamanqatha phakathi kwamagxa akho
• Ubuso obujikelezileyo
• ukutyeba kwakho
• Amanqaku okupinki
• buthathaka amathambo
• isifo seswekile
• igazi elonyukayo
• ulusu olubhityileyo
• ukuphola kancinci
• induna
• imijikelo yokuya exesheni ngokungaqhelekanga
• yehle i-libido
• ukudinwa
• ukudakumba

Ukuba usebenzise i-glucocorticoids ngaphezulu kweeveki ezimbalwa, ugqirha wakho uya kuyiphepha kancinci kancinci kunokuba uyeke ukuthatha konke kube kanye. Oku kunceda ukuthintela iziphumo zokurhoxa. Umzimba wakho ngokwendalo wenza ii-glucocorticoids, kodwa xa uqala ukuwathatha njengamayeza, umzimba wakho uphendula ngokwenza kancinci kuwo. Xa uyeka ukuthatha i-glucocorticoids, umzimba wakho ufuna ixesha lokuqala ukwenza okungaphezulu kwawo kumanqanaba aqhelekileyo kwakhona.

Thetha nogqirha wakho

I-Glucocorticoids inokuba ngamachiza aluncedo kunyango ezahlukeneyo. Nangona kunjalo, kubalulekile ukulungelelanisa isidingo sonyango lwe-glucocorticoid ngokuchasene neziphumo ebezingalindelekanga. Ukuba ugqirha wakho ukumisela unyango lwe-glucocorticoid kuwe, baxelele ngayo nayiphi na imiphumo emibi onayo. Kukwabalulekile ukuba uthathe iziyobisi ngokuchanekileyo njengoko kubekiwe, kubandakanya xa uziyeka. Ugqirha wakho unokukulahla amayeza akho kancinci ukuthintela ukurhoxa.