Yintoni i-mucormycosis, iimpawu kunye nonyango

Umxholo

• Iimpawu eziphambili kunye neempawu
• Iindidi ze-mucormycosis
• Izizathu ezinokubangela
• Uxilongo lwenziwa njani
• Unyango lweMucormycosis

I-Mucormycosis, eyayisaziwa njenge-zygomycosis, ligama elisetyenziselwa ukubhekisa kwiqela losulelo olubangelwa kukungunda komyalelo we-Mucorales, oqheleke kakhulu ngundo Rhizopus spp. Ezi zifo azisasazeki zisuka komnye umntu ziye komnye kwaye zihlala zixhaphakile kubantu abanesifo esingalunganga okanye abanesifo seswekile.

Esi sifo senzeka xa umngundo uphefumlelwe, usiya ngqo emiphungeni, okanye xa ungena emzimbeni ngokunqunyulwa kolusu, ukhokelela ekubonakaleni kweempawu ngokwelungu ebelisulelekile, kwaye kungakho nentloko ebuhlungu, umkhuhlane , ukudumba, ukuba bomvu ebusweni nokukhupha okukhulu emehlweni nasempumlweni. Xa i-mucormycosis ifikelela kwingqondo, ukuxhuzula, ubunzima bokuthetha kunye nokulahleka kwengqondo kusenokwenzeka.

Ukuchongwa kwe-mucormycosis kwenziwa ngugqirha oqhelekileyo okanye isifo esosulelayo ngokusebenzisa ikhompyuter ye-tomography kunye nenkcubeko yefungal kunye nonyango oluqhelekileyo lwenziwa ngokusetyenziswa kweziyobisi ezingena ngenaliti okanye ngomlomo, ezinje ngeAmphotericin B.

Iimpawu eziphambili kunye neempawu

Iimpawu kunye neempawu ze-mucormycosis zingahluka ngokwenqanaba le-immunocompromise yomntu kunye nelungu elichaphazeleke ngundo, kwaye kunokubakho:

• Impumlo: lelinye lamalungu achaphazeleka kakhulu sesi sifo kwaye likhokelela ekubonakaleni kweempawu ezifana ne-sinusitis, ezinje ngeempumlo ezixineneyo, iintlungu ezidleleni kunye ne-phlegm eluhlaza, kodwa kwezona meko zinzima, ukudumba ebusweni, ukulahleka kwethishu isibhakabhaka umlomo okanye intlala yempumlo;
• Amehlo: Ukubonakaliswa kwe-mucormycosis kunokubonwa kwiingxaki kumbono onjengobunzima bokubona, ukuqokelela ukukhutshwa okuphuzi kunye nokuvuvukala ngamehlo;
• Imiphunga: xa ifungi ifikelela kweli lungu, kunokwenzeka ukukhohlela ngesixa esikhulu sephlegm okanye igazi, iintlungu zesifuba kunye nobunzima bokuphefumla;
• Ubuchopho: eli lungu liyachaphazeleka xa i-mucormycosis isasazeka kwaye inokubangela iimpawu ezinje ngokuxhuzula, ukuthetha nzima, utshintsho kwimithambo-luvo yobuso kunye nokulahleka kwengqondo;
• Ulusu: Isikhunta seMucormycosis sinokuchaphazela imimandla yolusu, kwaye bomvu, buqine, budumbe, izilonda ezibuhlungu zinokubonakala kwaye, kwezinye iimeko, zinokuba ngamadyungudyungu kwaye zenze izilonda ezivulekileyo, ezimnyama.

Kwiimeko ezihambele phambili, umntu one-mucormycosis unokuba nebluish tinge kulusu kunye neminwe emfusa kwaye oku kungenxa yokungabikho kweoksijini okubangelwa kukuqokelelwa komngundo emiphungeni. Ukongeza, ukuba usulelo aluchongwanga lunyangwe, ukungunda kungasasazeka ngokukhawuleza kwamanye amalungu, ngakumbi ukuba umntu unamajoni omzimba athathaka kakhulu, afikelela kwizintso nentliziyo kwaye abeke ubomi bomntu emngciphekweni.

Iindidi ze-mucormycosis

I-Mucormycosis inokwahlulwa ngokweendidi ngokommandla wosulelo lomngundo, kwaye inokuba:

• I-Rhinocerebral mucormycosis, lolona hlobo luqhelekileyo lwesifo, uninzi lwezi meko zenzeka kubantu abanesifo seswekile. Kolu hlobo, ukungunda kusulela impumlo, iisono, amehlo kunye nomlomo;
• Iipulmonary mucormycosis, apho isikhunta sifikelela emiphungeni, esi sisibonakaliso sesibini esiqhelekileyo;
• Isicu somzimba esisikiweyo, equka ukusasazeka kwesifo sokungunda kwiindawo zolusu, ezinokufikelela nakwimisipha;
• Isisu somzimba esiswini, apho ukungunda kufikelela kwithumbu lesisu, kunqabile ukuba kwenzeke.

Kukho uhlobo lwe-mucormycosis, ebizwa ngokuba yi-disseminated, enqabileyo kwaye eyenzekayo xa i-fungi ifudukela kumalungu ahlukeneyo emzimbeni, njengentliziyo, izintso kunye nengqondo.

Izizathu ezinokubangela

I-Mucormycosis liqela losulelo olubangelwa kukungunda komyalelo we-Mucorales, eyona nto ixhaphakileyo Rhizopus spp., ezifumaneka kwiindawo ezahlukeneyo kwindalo esingqongileyo, ezinje ngezityalo, umhlaba, iziqhamo kunye nokubola kweemveliso.

Ngokwesiqhelo, ezi fungi azibangeli zingxaki zempilo, njengoko zinokulwa amajoni omzimba. Ukuphuhliswa kwezifo kwenzeka ikakhulu kubantu abanamajoni omzimba angalunganga, ukuba rhoqo rhoqo kubantu abanesifo seswekile. Ukongeza, abantu abanokuzikhusela okuphantsi ngenxa yezifo ezinjenge-HIV, ukusetyenziswa kweziyobisi ezikhuselayo okanye uhlobo oluthile lokufakelwa, olufana nomongo wethambo okanye amalungu, banomngcipheko ophezulu wokufumana isifo se-mucormycosis.

Uxilongo lwenziwa njani

Ukuchongwa kwe-mucormycosis kwenziwa ngugqirha oqhelekileyo okanye isifo esosulelayo ngokuvavanya imbali yezempilo yomntu kunye nekhompyuter yecomputer, esebenza ukuqinisekisa indawo kunye nobungakanani bosulelo. Inkcubeko yesikhohlela nayo iyenziwa, esekwe ekuhlalutyeni imfihlo yamaphaphu ukuze ichonge ukungunda okunxulumene nosulelo.

Ngamanye amaxesha ugqirha unokucela uviwo lweemolekyuli, ezinje nge-PCR, ukuba ichonge uhlobo lwefungus kwaye, kuxhomekeke kubuchwephesha obusetyenzisiweyo, isixa esikhoyo kumzimba, kunye nemifanekiso yokujonga ngemagneti yokuphanda ukuba ngaba i-mucormycosis ifikile ulwakhiwo lobuchopho, umzekelo. Olu vavanyo kufuneka lwenziwe ngokukhawuleza, kuba ngokukhawuleza ukuxilongwa kwenziwa, maninzi amathuba okuphelisa usulelo.

Unyango lweMucormycosis

Unyango lwe-mucormycosis kufuneka lwenziwe ngokukhawuleza, kwakamsinya nje ukuba isifo sifunyaniswe, ukuze amathuba okunyanga abe makhulu kwaye kufuneka enziwe ngokwesindululo sikagqirha, kunye nokusetyenziswa kwe-antifungals ngqo emthanjeni, njenge Amphotericin, B, okanye iPosaconazole, umzekelo. Kubalulekile ukuba amayeza asetyenziswe ngokwesindululo sonyango kwaye unyango lumiswe nokuba kungasekho zimpawu.

Ukongeza, kuxhomekeke kubuzaza bentsholongwane, ugqirha unokucebisa ukuba enze utyando ukuze kususwe izicwili necrotic ezibangelwa ngundo, ebizwa ngokuba kukususwa. Unyango lwegumbi le-Hyperbaric lunokucetyiswa, nangona kunjalo, azikabikho izifundo ezaneleyo zokubonisa ukusebenza kwazo. Funda ngakumbi malunga nendlela igumbi le-hyperbaric elisebenza ngayo.