Yintoni uThixo? Izibonelelo, ukuSebenzisa, kunye neZiphumo eziPhakathi

Umxholo

• Izibonelelo ezinokubakho zemulungu
• Inganciphisa iimvakalelo zoxinzelelo
• Ngamana unokukhusela ekubanjweni kwesithuthwane
• Ngaba banokuba neempawu zokunceda iintlungu
• Ezinye izibonelelo ezinokubakho
• Ukusetyenziswa kunye nokhuseleko
• Umgca wezantsi

Mulungu (Erythruna mulungu) ngumthi wokuhombisa wemveli waseBrazil.

Ngamanye amaxesha ibizwa ngokuba ngumthi wekorale ngenxa yeentyatyambo zayo ezibomvu. Imbewu yayo, i-bark, kunye neendawo zasemoyeni ziye zasetyenziswa kangangeenkulungwane kunyango lwesintu lwaseBrazil ().

Ngokwembali, i-mulungu yayisetyenziselwa iinjongo ezahlukeneyo, njengokunciphisa iintlungu, ukunceda ukulala, uxinzelelo lwegazi olusezantsi, kunye nokunyanga iimeko ezinje ngoxinzelelo, uxinzelelo kunye nokuxhuzula ().

Eli nqaku livavanya izibonelelo ze-mulungu, ukusetyenziswa, kunye neziphumo ebezingalindelekanga ezinokubakho.

Izibonelelo ezinokubakho zemulungu

Uninzi lwezinto ezinokubakho zezempilo ze-mulungu zinokubangelwa ziikhompawundi zayo eziphambili (+) - erythravine kunye (+) - 11cy-hydroxyerythravine, eziye zadityaniswa nokuthomalalisa iintlungu kunye nokunciphisa uxinzelelo kunye nokuxhuzula (,, 4).

Inganciphisa iimvakalelo zoxinzelelo

U-Mulungu kudala esetyenziswa kunyango lwesintu ukunyanga uxinzelelo.

Izifundo zezilwanyana zifumanise ukuba iikhompawundi ze-mulungu (+) - erythravine kunye (+) - 11cy-hydroxyerythravine inokuba neziphumo ezinamandla zokulwa noxinzelelo, ezifanayo nezo zeyeza likaValium (diazepam) (,).

Isifundo esincinci sabantu kubantu abangama-30 abenza utyando lwamazinyo baqaphela ukuba ukuthatha i-500 mg ye-mulungu ngaphambi kwenkqubo kuncede ukunciphisa uxinzelelo ngaphezulu kwe-placebo ().

Uphononongo lweetyhubhu zovavanyo lubonisa ukuba iipropathi zokulwa noxinzelelo ze-mulungu kunokwenzeka ukuba zivele kumandla ayo okuthintela i-nicotinic acetylcholine receptors, edlala indima ekulawuleni iimvakalelo zoxinzelelo (,, 8).

Nangona kunjalo, izifundo ezingaphezulu zabantu kwi-mulungu kunye noxinzelelo ziyafuneka ngaphambi kokuba kucetyiswe ngale njongo.

Ngamana unokukhusela ekubanjweni kwesithuthwane

Isathuthwane yimeko engapheliyo yemithambo-luvo ebonisa ukuxhuzula okuphindaphindayo.

Ngaphandle kokufumaneka kwamayeza alwa nesathuthwane, malunga ne-30-40% yabantu abanesathuthwane abangayiphenduliyo iyeza eliqhelekileyo lokuxhuzula. Esi sesinye sezizathu zokuba ezinye iindlela zonyango ziye zanda ().

Ityhubhu yovavanyo kunye nezifundo zezilwanyana zicebisa ukuba i-mulungu kunye nezinto zayo (+) - erythravine kunye (+) - 11cy-hydroxy-erythravine inokunceda ekukhuseleni ukuxhuzula (,).

Uphononongo kwiimpuku ezinokuxhuzula kwafunyanwa abo baphathwa nge (+) - erythravine kunye (+) - 11α-hydroxy-erythravine bafumana ukubanjwa okumbalwa kwaye baphila ixesha elide. Ezi khompawundi zikwakhusele kwimemori yexesha elifutshane kunye nemicimbi yokufunda ().

Ngelixa indlela eyiyo emva kweepropathi zokulwa nesifo sokuwa sika-mulungu ingacacanga, olunye uphando lufumanise ukuba (+) - erythravine kunye (+) - 11cy-hydroxy-erythravine inokucinezela umsebenzi wee-receptors ezidlala indima kwisifo sokuwa ().

Nangona olu phando luthembisa, izifundo ezingaphezulu zabantu ziyafuneka kwiipropathi zokulwa nesifo sokuxhuzula se-mulungu ngaphambi kokuba icetyiswe ngenxa yesi sizathu.

Ngaba banokuba neempawu zokunceda iintlungu

Izifundo zezilwanyana zibonisa ukuba i-mulungu inokuba neempawu zokuthomalalisa iintlungu.

Uphononongo olwenziwe ngo-2003 kwiimpuku luye lwaphawula ukuba iimpuku ezanyangwa nge-mulungu ezikhutshwe zinamava okunciphisa isisu kwaye zabonisa iimpawu ezimbalwa zentlungu kunalezo ziphathwe nge-placebo ().

Kwangokunjalo, olunye uphononongo lweempuku lufumanise ukuba abo baphathwe nge-mulungu bakhupha amava okunciphisa isisu kwaye babonisa ukuncipha kokumakisha. Oku kubonisa ukuba i-mulungu nayo inezinto ezichasayo (4).

Kukholelwa ukuba i-mulungu inokuba neempembelelo ze-antinociceptive, oko kuthetha ukuba inokunciphisa uvakalelo lweentlungu ezivela kwiiseli zemithambo-luvo.

Isizathu esibangela ukuba kubekho iipropathi zokuphelisa iintlungu asikacaci, kodwa i-mulungu ibonakala inciphisa iintlungu ezizimeleyo kwinkqubo ye-opioid, eyona nto iphambili kwezonyango ().

Nangona ezi zifundo zithembisa, uphando oluthe kratya lomntu luyafuneka.

Ezinye izibonelelo ezinokubakho

U-Mulungu unokubonelela ngezinye izibonelelo ezinokubakho, kubandakanya:

• Ngamana unokunciphisa ukudumba. Izifundo ezininzi zezilwanyana zifumanise ukuba izicatshulwa ze-mulungu zinokunciphisa amanqaku okudumba (4,).
• Ngamana unokunceda ukunyanga iimpawu zesifuba. Uphando lwezilwanyana luqwalasele ukuba isicatshulwa se-mulungu sinokunciphisa iimpawu zesifuba kunye nokunciphisa ukudumba ().

U-Mulungu unxulunyaniswe nezibonelelo ezininzi ezinokubakho, ezinje ngokuthomalalisa iintlungu kunye nokunciphisa uxinzelelo, ukuxhuzula, iimpawu zesifuba kunye nokudumba. Nangona kunjalo, uninzi lophando lwenziwe kwizilwanyana, kwaye kufuneka kwenziwe izifundo ezingakumbi zabantu.

Ukusetyenziswa kunye nokhuseleko

I-Mulungu inokuthengwa kwezinye iivenkile zokutya ezempilo nakwi-Intanethi.

Iza ngeendlela ezininzi, kubandakanya i-tincture kunye nomgubo onokuthi unyibilikiswe emanzini afudumeleyo ukwenza iti ye-mulungu.

Akukho lwazi lwaneleyo lwenzululwazi ukumisela idosi efanelekileyo, kwaye kukho ulwazi olunqunyelweyo kukhuseleko lwe-mulungu ebantwini.

Kwisifundo esinye, abantu baxele ukozela emva kokuthatha isicatshulwa se-mulungu ().

Ngapha koko, kukho inkxalabo yokuba i-mulungu inokuhlisa uxinzelelo lwegazi ().

Abantu abasengozini, njengabantwana, abasetyhini abakhulelweyo, kunye nabantu abadala, kufuneka bakuphephe ukuthatha iimveliso ze-mulungu, njengoko ukhuseleko lwayo lungakhange lusekwe kula maqela.

Ngokubanzi, ulwazi lwezenzululwazi ngezibonelelo zika-mulungu kunye nokhuseleko alonelanga ukuyicebisa ngeenjongo zempilo.

Kukwafanelekile ukuba uqaphele ukuba - njengezinye izongezo zemifuno - izongezo ze-mulungu ubukhulu becala azilawulwa kwaye khange zivavanyelwe ukhuseleko. Ngamanye amaxesha, azinakho ukuqulatha izinto ezidweliswe kwileyibhile okanye zingcoliswe zezinye izinto.

I-Mulungu inokuthengwa njenge-tincture kunye nomgubo. Nangona kunjalo, kukho uphando olulinganiselweyo lomntu kukhuseleko kunye neenzuzo zalo, ngoko ke akufuneki ukuba kucetyiswe iinjongo zempilo kude kufumaneke uphando lomntu ngakumbi.

Umgca wezantsi

U-Mulungu ngumthi ozalelwe eBrazil onokuthi ubonelele ngezibonelelo ezahlukeneyo zempilo.

Ityhubhu yovavanyo kunye nophando lwezilwanyana lubonisa ukuba inokuthomalalisa iintlungu kunye nokunciphisa uxinzelelo, ukuxhuzula, ukudumba, kunye neempawu zesifuba.

Nangona kunjalo, luthintelwe uphando lomntu kwizibonelelo ze-mulungu kunye nokhuseleko. Izifundo ezingakumbi zabantu ziyafuneka ngaphambi kokuba kucetyiswe iinjongo zempilo.