Yintoni enokuba zi-neutrophils eziphezulu nezisezantsi
Umxholo
I-neutrophils luhlobo lweeukocyte kwaye, ke, linoxanduva lokukhusela umzimba, ukuba inani lazo lenyuke egazini xa kukho usulelo okanye ukudumba okwenzekayo. I-neutrophil efumaneka kwelona nani likhulu lijikelezayo yisahlulo se-neutrophil, ekwabizwa ngokuba yi-neutrophil esele ikhulile, ejongene nokubandakanya iiseli ezosulelekileyo okanye ezonzakeleyo emva koko uzisuse.
Ixabiso eliqhelekileyo lesalathiso lezahlulo ze-neutrophil ezijikeleziswa egazini lingahluka ngokwelabhoratri, nangona kunjalo, ngokubanzi isusela kwi-1600 ukuya kwi-8000 yezahlulo ze-neutrophils nge-mm³ yegazi. Ke, xa i-neutrophils iphezulu ihlala ibonisa ukuba umntu unesifo esithile se-bacterial okanye fungal, kuba le seli isebenza ukukhusela umzimba.
Kuvavanyo lwegazi, ukongeza ekuboniseni isixa se-neutrophils esahlulweyo, inani le-eosinophil, i-basophils kunye ne-rod kunye ne-neutrophils ye-stick iyachazwa, eziyi-neutrophils esele zenziwe ngenjongo yokulwa nosulelo kwaye zikhokelela ekwakhiweni neutrophils zahlulo.
Isixa se-neutrophils sinokuvavanywa ngokwenza inani elipheleleyo legazi, apho kunokujongwa lonke uthotho lwegazi elimhlophe. Ii-leukocyte zivavanywa kwinxalenye ethile yokubala kwegazi, i-leukocyte enokuthi ibonise:
1. I-neutrophils ende
Ukonyuka kwesixa se-neutrophils, ekwabizwa ngokuba yi-neutrophilia, kunokwenzeka ngenxa yeemeko ezininzi, eyona iphambili yile:
- Usulelo;
- Iingxaki zokudumba;
- Isifo seswekile;
- IUremia;
- Eclampsia xa ukhulelwe;
- Isibindi necrosis;
- Leukemia ezingapheliyo myeloid;
- Iposi-splenectomy polycythemia;
- I-hemolytic anemia;
- Iimpawu zeMyeloproliferative;
- Ukopha;
- Ukutsha;
- Ukutshatyalaliswa kombane;
- Umhlaza.
I-Neutrophilia ingenzeka kwakhona ngenxa yeemeko zomzimba, ezinje ngeentsana, ngexesha lokuzalwa komntwana, emva kweziqendu zokugabha okuphindaphindiweyo, uloyiko, uxinzelelo, ukusetyenziswa kweziyobisi nge-adrenaline, ixhala nasemva kokuzibaxa izinto zomzimba. Ke, ukuba ixabiso le-neutrophils liphezulu, ugqirha unokuyalela ezinye iimvavanyo zokuqonda isifo ukuba zichonge unobangela kwaye aqalise unyango olufanelekileyo. Bona ngakumbi malunga ne-neutrophilia.
2. I-neutrophils ephantsi
Ukwehla kwenani le-neutrophils, ekwabizwa ngokuba yi-neutropenia, kunokwenzeka ngenxa:
- I-aplastic, megaloblastic okanye i-iron anemia;
- Wegazi;
- IHypothyroidism;
- Ukusetyenziswa kwamayeza;
- Izifo ezisebenza ngokuzenzekelayo, ezinje ngeLupus Erythematosus;
- IMyelofibrosis;
- Isibindi.
Ukongeza, kunokubakho i-neonatal neutropenia kwimeko yosulelo olukhulu ziintsholongwane okanye ibacteria emva kokuzalwa. Abantwana abane-Down syndrome nabo banama-neutrophils aphantsi ngaphandle kweengxaki zempilo.
Kwimeko ye-neutropenia, ugqirha unokucebisa ukuba enze i-myelogram ukuphanda unobangela wokuhla kwenani lee-neutrophils ezahluliweyo egazini, ukongeza ekujongeni ukuba ngaba kukho naluphi na utshintsho olunxulumene nokuveliswa kweeseli zangaphambi kwentsimbi kumongo wethambo .