INoradrenaline

Umxholo

• Yenzelwe ntoni
• Kusetyenziswa kwanjani
• Indlela yokusebenza
• Ngubani ongafanele asebenzise
• Iziphumo ebezingalindelekanga ezinokwenzeka

I-Norepinephrine, ekwabizwa ngokuba yi-norepinephrine, sisiyobisi esisetyenziselwa ukulawula uxinzelelo lwegazi kwiindawo ezithile ze-hypotensive kwaye njengesixhobo sonyango lokubanjwa kwentliziyo kunye ne-hypotension enzulu.

Eliyeza liyafumaneka njengenaliti, ekufuneka isetyenziswe kuphela phantsi kwengcebiso yezonyango kwaye ulawulo lwayo kufuneka lwenziwe yingcali yezempilo.

Yenzelwe ntoni

I-Norepinephrine sisiyobisi esiboniswe ukulawula uxinzelelo lwegazi kwiindawo ezithile ze-hypotensive, kwiimeko ezinje nge-pheochromocytomectomy, sympathectomy, polio, myocardial infarction, septicemia, transfusion igazi kunye nokusabela kumayeza.

Ukongeza, inokusetyenziswa njengoncedo kunyango lokubanjwa kwentliziyo kunye ne-hypotension enzulu.

Kusetyenziswa kwanjani

I-Norepinephrin sisiyobisi ekufuneka silawulwe kuphela yingcali yezempilo, ngaphakathi, ngaphakathi kwisisombululo esincomekayo. Umthamo oza kulawulwa kufuneka ube ngumntu ngamnye kwaye ugqitywe ngugqirha.

Indlela yokusebenza

I-Norepinephrin yintsholongwane kunye nomsebenzi ohambelana nokuhambelana, ukusebenza ngokukhawuleza, kunye nefuthe elibonakalayo kwi-alpha-adrenergic receptors kwaye ingabonakali kakhulu kwi-beta-adrenergic receptors. Ke, eyona nto ibaluleke kakhulu kuyo yenzeka ekunyuseni uxinzelelo lwegazi, olusisiphumo se-alpha-eshukumisayo, esibangela ukuba i-vasoconstriction, inciphise ukuhamba kwegazi kwizintso, isibindi, ulusu kwaye, rhoqo, isisipha samathambo.

Ngubani ongafanele asebenzise

INoradrenaline akufuneki isetyenziswe kubantu abaxhalabisayo kumacandelo efomula okanye nge-mesenteric okanye peripheral vascular thrombosis.

Ukongeza, akufuneki ukuba ifakwe kubantu abane-hypotensive ngenxa yokunqongophala kwegazi, ngaphandle nje kokuba inyathelo likaxakeka lokugcina i-coronary kunye ne-cerebral arterial perfusion de kube kugqityiwe ukunyanga kwegazi, nokuba nge-anesthesia nge-cyclopropane kunye ne-halothane, njengoko i-tachycardia ye-ventricular okanye i-fibrillation inokwenzeka.

Iziphumo ebezingalindelekanga ezinokwenzeka

Ezinye iziphumo ebezingalindelekanga ezinokuthi zenzeke emva kolawulo lwe-norepinephrine kukulimala kwe-ischemic, ukwehla kwenqanaba lentliziyo, unxunguphalo, intloko ebambekayo, ukuphefumla nzima kunye necrosis kwindawo yenaliti.