Umbhali: Charles Brown
Umhla Wokudalwa: 1 Eyomdumba 2021
Hlaziya Umhla: 21 Eyenkanga 2024
Anonim
#PAMIDRONATO
Ividiyo: #PAMIDRONATO

Umxholo

I-Pamidronate yinto esebenzayo kwiyeza elichasene ne-hypercalcemic eyaziwa ngokuthengisa njenge-Aredia.

Eli chiza lokusetyenziswa ngenaliti libonakalisiwe kwisifo sikaPaget, i-osteolysis kuba inqanda ukubola kwethambo ngeendlela ezininzi, ukunciphisa iimpawu zezifo.

Iimpawu Pamidronate

Isifo seethambo likaPaget; hypercalcemia (enxulunyaniswa neoplasia); i-osteolysis (ebangelwa yi-tumor yesifuba okanye i-myeloma).

Ixabiso le Pamidronato

Ixabiso leziyobisi alifumanekanga.

Iziphumo ebezingalindelekanga zePamidronate

Ukunciphisa i-potassium yegazi; kunciphise iiphosphate egazini; irhashalala; ukuqina; ubuhlungu; Ngokucofa ukudumba; ukudumba umthambo; umkhuhlane osezantsi okwethutyana.

Kwiimeko zesifo sikaPaget: ukwanda koxinzelelo lwegazi; iintlungu zethambo; intloko ebuhlungu; intlungu edibeneyo.

Kwiimeko ze-osteolysisanemia; ukuphelelwa ngumdla wokutya; ukudinwa; ubunzima bokuphefumla ukuqunjelwa; isisu esibuhlungu; intlungu edibeneyo; ukukhohlela; intloko ebuhlungu.


Ukungqinelana nePamidronate

Umngcipheko wokukhulelwa C; Ukuncancisa: izigulana ezinokungabikho komzimba kwi-bisphosphonates; Ukuqina kwenyani kulo naliphi na ifomula yefomula.

Uyisebenzisa kanjani iPamidronate

Ukusetyenziswa okungafunekiyo

Abantu abadala

  • HypercalcemiaI-60 mg ilawulwa ngaphezulu kweeyure ezingama-4 ukuya kwezingama-24 (i-hypercalcemia e-coral calcium elungisiweyo engaphezulu kwe-13.5 mg / dL-inokufuna i-90 mg ilawulwe ngaphezulu kweeyure ezingama-24).
  • Izigulana ezingasebenzi kakuhle kwizintso okanye nge-hypercalcemia ethambileyo: I-60 mg ilawulwa ngaphezulu kweeyure ezingama-4 ukuya kwezi-24.

Iintloko phezulu: ukuba i-hypercalcemia iphinda ibuye, unyango olutsha lunokuqwalaselwa okoko kude kudlule iintsuku ezisi-7.

  • Isifo sikaPaget sethambo: Itotali iyonke ye-90 ukuya kwi-180 mg ngexesha lonyango; idosi iyonke inokulawulwa kwi-30 mg yonke imihla ngeentsuku ezi-3 zilandelelana okanye i-30 mg kanye ngeveki iiveki ezi-6. Izinga lolawulo lihlala li-15 mg ngeyure.
  • I-osteolysis eyenziwe nge-tumor (kumhlaza wesifuba): I-90 mg ilawulwa ngaphezulu kweeyure ze-2, rhoqo kwi-3 okanye kwiiveki ze-4; (kwi-myeloma): 90 mg ilawulwa ngaphezulu kweeyure ezingama-2, kanye ngenyanga.

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