I-Pantoprazole, ithebhulethi yomlomo

Umxholo

• Amagqabantshintshi epantoprazole
• Izilumkiso ezibalulekileyo
• Yintoni i-pantoprazole?
• Kutheni isetyenziswa
• Ingaba isebenza kanjani
• Iziphumo ebezingalindelekanga zePantoprazole
• Iziphumo eziqhelekileyo ezichaphazelekayo
• Iziphumo ebezingalindelekanga ezimandundu
• I-Pantoprazole inokusebenzisana namanye amayeza
• Iziyobisi ze-HIV
• I-Anticoagulant
• Iziyobisi ezichaphazeleka sisisu pH
• Iyeza lomhlaza
• Izilumkiso zePantoprazole
• Isilumkiso somzimba
• Izilumkiso zabantu abaneemeko ezithile zempilo
• Izilumkiso kwamanye amaqela
• Uyithatha njani ipantoprazole
• Iifom kunye namandla
• Umyinge wesifo se-reflux se-gastroesophageal (GERD)
• Isisombululo semveliso ye-asidi engaphezulu, njenge-Zollinger-Ellison syndrome
• Thatha njengoko kuyalelwe
• Ukuqwalaselwa okubalulekileyo kokuthatha i-pantoprazole
• Ngokubanzi
• Ukugcina
• Ukuzalisa kwakhona
• Ukubeka iliso kwezonyango
• Ukuhamba
• Ngaba zikhona ezinye iindlela?

Amagqabantshintshi epantoprazole

1. Ithebhulethi yomlomo wePantoprazole iyafumaneka njengesiqhelo kunye neli gama lophawu. Igama leBrand: Protonix.
2. I-Pantoprazole iza ngeendlela ezintathu: ithebhulethi yomlomo, ukunqunyanyiswa ngomlomo, kunye nefom yegazi (IV) efakwe kumthambo wakho ngumboneleli wezempilo.
3. Ithebhulethi yomlomo wePantoprazole isetyenziselwa ukunciphisa isixa sesisu esenziwe ngumzimba wakho. Inceda ukunyanga iimpawu ezibuhlungu ezibangelwa ziimeko ezinje ngesifo se-reflux se-gastroesophageal (GERD).

Izilumkiso ezibalulekileyo

• Isilumkiso sokusetyenziswa kwexesha elide: Ukusetyenziswa kwexesha elide kwe-pantoprazole kunokukhokelela kumngcipheko okhulayo weziphumo ebezingalindelekanga ezithile kunye neengxaki. Oku kubandakanya:
  • Umngcipheko owandileyo wokuqhekeka kwethambo kubantu abathatha ngaphezulu, iidosi ezininzi zemihla ngemihla ngaphezulu konyaka omnye.
  • Ukusilela kweVitamin B-12, enokuthi ikhokelele kumonakalo omkhulu we-nerve kunye nokuwohloka kwemisebenzi yobuchopho. Oku kuye kwabonwa kwabanye abantu bethatha i-pantoprazole ixesha elingaphezulu kweminyaka emithathu.
  • Ukudumba okungapheliyo kwesisu esiswini (atrophic gastritis) xa uthatha i-pantoprazole ixesha elide. Abantu abane H. pylori basemngciphekweni omkhulu.
  • I-magnesium yegazi ephantsi (i-hypomagnesemia), oku kuye kwabonwa kwabanye abantu bethatha i-pantoprazole kangangeenyanga ezintathu. Rhoqo, kwenzeka emva konyaka okanye nangaphezulu unyango.
• Isilumkiso sohudo: Urhudo olubi olubangelwa IClostridium difficile Iibhaktheriya zingenzeka kwabanye abantu baphathwa nge-pantoprazole, ngakumbi abantu abasesibhedlele.
• Isilumkiso somzimba: Nangona kunqabile, i-pantoprazole inokubangela ukusabela komzimba. Iimpawu zingabandakanya ukukhawuleza, ukuvuvukala, okanye iingxaki zokuphefumla. Oku kunokuqhubela phambili kwi-nephritis yangaphakathi, isifo sezintso esinokubangela ukusilela kwezintso. Iimpawu zale meko zibandakanya:
  • isicaphucaphu okanye ukugabha
  • ifiva
  • irhashalala
  • ukudideka
  • igazi kumchamo wakho
  • ukudumba
  • uxinzelelo lwegazi oluphakamileyo
• I-lupus erythematosus kunye nesilumkiso se-lupus erythematosus: I-Pantoprazole inokubangela i-lupus erythematosus (CLE) kunye ne-systemic lupus erythematosus (SLE). I-CLE kunye ne-SLE zizifo ezizimele. Iimpawu zeCLE zinokuvela kurhwaphilizo eluswini nasempumlweni, kuye ekuphakameni, kukho isikhumba, kubomvu okanye kungqombela kwiindawo ezithile zomzimba. Iimpawu ze-SLE zingabandakanya umkhuhlane, ukudinwa, ukwehla kobunzima, amahlwili egazi, ukutsha kwentliziyo kunye nesisu esibuhlungu. Ukuba unayo nayiphi na le mpawu, biza ugqirha wakho.
• Isilumkiso se-Fundic gland polyps: Ukusetyenziswa kwexesha elide (ngakumbi ngaphezulu konyaka) kwipopoprazole kunokubangela i-fundic gland polyps. Ezi polyps kukukhula kwilindle lesisu sakho esinokuba ngumhlaza. Ukukunceda ukukhusela ezi polyp, kuya kufuneka usebenzise eli chiza ixesha elifutshane kangangoko.

Yintoni i-pantoprazole?

Ithebhulethi yomlomo wePantoprazole sisiyobisi esikho njengesiyobisi IProtonix. Ikwafumaneka njengechiza elenza la machiza. Amachiza enziwe afana nalawo aveliswe ngumenzi ahlala exabisa ixabiso lawo kunexabiso lawo. Ngamanye amaxesha, azinakufumaneka kuwo onke amandla okanye iifom njengegama legama lophawu.

I-Pantoprazole iza ngeendlela ezintathu: ithebhulethi yomlomo, ukumiswa kolwelo ngomlomo, kunye nefom yegazi (IV) efakwe kumthambo wakho ngumboneleli wezempilo.

Kutheni isetyenziswa

Ithebhulethi yomlomo wePantoprazole isetyenziselwa ukunciphisa isixa sesisu esenziwe ngumzimba wakho. Inceda ukunyanga iimpawu ezibuhlungu ezibangelwa ziimeko ezinje ngesifo se-reflux se-gastroesophageal (GERD). Nge-GERD, iijusi zesisu zihamba phezulu zisuka kwisisu sakho ziye kwi-esophagus.

Ithebhulethi yomlomo wePantoprazole ikwasetyenziselwa ukunyanga ezinye iimeko apho isisu senza i-asidi engaphezulu, njengeZollinger-Ellison syndrome.

Ingaba isebenza kanjani

IPantoprazole ikudidi lweziyobisi ekuthiwa yiproton pump inhibitors. Kuyasebenza ukuvala iiseli zokumpompa iasidi esiswini sakho. Iyanciphisa inani lesisu esiswini kwaye inceda ukunciphisa iimpawu ezibuhlungu ezinxulumene neemeko ezinje ngeGERD.

Iziphumo ebezingalindelekanga zePantoprazole

Ithebhulethi yomlomo wePantoprazole ayibangeli ukozela. Nangona kunjalo, inokubangela ezinye iziphumo ebezingalindelekanga.

Iziphumo eziqhelekileyo ezichaphazelekayo

Iziphumo eziqhelekileyo ezinokuthi zenzeke nge-pantoprazole zibandakanya:

• intloko ebuhlungu
• urhudo
• isisu esibuhlungu
• isicaphucaphu okanye ukugabha
• irhasi
• isiyezi
• intlungu edibeneyo

Iziphumo ebezingalindelekanga ezimandundu

Shayela ugqirha wakho ngokukhawuleza ukuba unemiphumo emibi. Tsalela umnxeba ku-911 ukuba iimpawu zakho ziziva zisongela ubomi okanye ukuba ucinga ukuba unempilo kaxakeka. Iziphumo ebezingalindelekanga ezimandundu kunye neempawu zazo zinokubandakanya oku kulandelayo:

• Amanqanaba e-magnesium asezantsi. Sebenzisa eli chiza iinyanga ezintathu okanye nangaphezulu kunokubangela amanqanaba e-magnesium asezantsi. Iimpawu zingabandakanya:
  • ukuxhuzula
  • ukubetha kwentliziyo okungaqhelekanga okanye okukhawulezayo
  • ukungcangcazela
  • jita
  • ubuthathaka bemisipha
  • isiyezi
  • spasms zezandla neenyawo zakho
  • iicramps okanye izihlunu
  • Spasm yebhokisi yakho yelizwi
• Ukusilela kweVitamin B-12. Sebenzisa eli chiza ixesha elingaphezulu kweminyaka emithathu kunokwenza ukuba kubenzima emzimbeni wakho ukufumana i-vitamin B-12. Iimpawu zingabandakanya:
  • uvalo
  • i-neuritis (ukudumba kwemithambo-luvo)
  • Ukuba ndindisholo okanye ukubetha ezandleni nasezinyaweni
  • Ulungelelwaniso olubi lweemisipha
  • utshintsho ekuhambeni kwexesha
• Urhudo oluqatha. Oku kunokubangelwa IClostridium difficile usulelo emathunjini akho. Iimpawu zingabandakanya:
  • isitulo samanzi
  • isisu esibuhlungu
  • umkhuhlane ongapheliyo
• Ukuqhekeka kwamathambo
• Ukonakala kwezintso. Iimpawu zingabandakanya:
  • iintlungu zeplanti (iintlungu kwicala lakho nasemqolo)
  • utshintsho ekuchameni
• I-lupus erythematosus (CLE) enqamlezileyo. Iimpawu zingabandakanya:
  • irhashalala eluswini nasempumlweni
  • ukuphakama okubomvu, okubomvu, obomvu okanye obomvu emzimbeni wakho
• Inkqubo ye lupus erythematosus (SLE). Iimpawu zingabandakanya:
  • ifiva
  • ukudinwa
  • ukuhla ukusinda
  • amahlwili egazi
  • isilungulela
• I-Fundic gland polyps (ayisoloko ibangela iimpawu)

Iphepha elichazayo ukuba awusenanto oyifunayo: Injongo yethu kukukunika olona lwazi lufanelekileyo nolukhoyo ngoku. Nangona kunjalo, ngenxa yokuba iziyobisi zichaphazela umntu ngamnye ngokwahlukileyo, asinakuqinisekisa ukuba olu lwazi lubandakanya zonke iziphumo ebezingalindelekanga ezinokubakho. Olu lwazi aluthathi ndawo yengcebiso yezonyango. Soloko uxoxa ngeziphumo ebezingalindelekanga ezinokwenzeka kunye nomboneleli wezempilo oyaziyo imbali yakho yezonyango.

I-Pantoprazole inokusebenzisana namanye amayeza

Ithebhulethi yomlomo wePantoprazole inokusebenzisana namanye amayeza, amayeza, okanye iivithamini onokuthi uzithathe. Kungenxa yoko le nto ugqirha wakho kufuneka alawule onke amayeza akho ngononophelo. Ukuba unomdla malunga nokuba eli chiza linokusebenzisana njani nenye into oyithathayo, thetha nogqirha wakho okanye usokhemesti.

Ukukunceda ukunqanda ukusebenzisana, ugqirha wakho kufuneka alawule onke amayeza ngononophelo. Qiniseka ukuba uxelela ugqirha wakho ngawo onke amayeza, iivithamini, okanye imifuno oyithathayo. Ukufumanisa ukuba eli chiza linokusebenzisana njani nenye into oyithathayo, thetha nogqirha wakho okanye usokhemesti.

Imizekelo yamachiza anokubangela ukusebenzisana ne-pantoprazole zidweliswe apha ngezantsi.

Iziyobisi ze-HIV

Ukuthatha amachiza athile e-HIV nge-pantoprazole ayikhuthazwa. I-Pantoprazole inokunciphisa kakhulu inani lala machiza emzimbeni wakho. Oku kunganciphisa amandla abo okulawula usulelo lwe-HIV. La machiza ngala:

• mzing
• mzwqdb

I-Anticoagulant

Abanye abantu bathatha iwarfarin nge-pantoprazole inokuba namava okunyuka kwe-INR kunye nexesha leprothrombin (PT). Oku kunokukhokelela kumngcipheko wokopha kakhulu. Ukuba uthatha la machiza kunye, ugqirha wakho kufuneka akuqwalasele ukonyuka kwe-INR kunye ne-PT.

Iziyobisi ezichaphazeleka sisisu pH

I-Pantoprazole ichaphazela amanqanaba e-asidi esiswini. Ngenxa yoko, inokunciphisa ukufunxeka komzimba wakho kumachiza athile anovakalelo kwiziphumo zokuncipha kwesisu esiswini. Esi siphumo singenza la mayeza angasebenzi kakuhle.

Imizekelo yala machiza ibandakanya:

• ketoconazole
• ampicillin
• mzing
• iityiwa zentsimbi
• erlotinib
• mycophenolate mofetil

Iyeza lomhlaza

Ukuthatha imethotrexate nge-pantoprazole kunokunyusa inani lemethotrexate emzimbeni wakho. Ukuba uthatha iidosi eziphezulu ze-methotrexate, ugqirha wakho unokuyeka ukuthatha i-pantoprazole ngexesha lonyango lwakho lwe-methotrexate.

Iphepha elichazayo ukuba awusenanto oyifunayo: Injongo yethu kukukunika olona lwazi lufanelekileyo nolukhoyo ngoku. Nangona kunjalo, ngenxa yokuba iziyobisi zinxibelelana ngokwahlukileyo kumntu ngamnye, asinakuqinisekisa ukuba olu lwazi lubandakanya lonke unxibelelwano olunokwenzeka. Olu lwazi aluthathi ndawo yengcebiso yezonyango. Soloko uthetha nomboneleli wakho wezempilo malunga nokunxibelelana okunokubakho nawo onke amayeza amiselweyo, iivithamini, amayeza kunye nezongezo, kunye neziyobisi ezingaphaya kwekhawunta ozithathayo.

Izilumkiso zePantoprazole

Ithebhulethi yomlomo wePantoprazole iza nezilumkiso ezininzi.

Isilumkiso somzimba

Nangona kunqabile, i-pantoprazole inokubangela ukusabela komzimba. Iimpawu zingabandakanya ukukhawuleza, ukuvuvukala, okanye iingxaki zokuphefumla.

Ukuphendula ngokuthe ngqo kunokuqhubela phambili kwi-nephritis yangaphakathi, isifo sezintso esinokubangela ukusilela kwezintso. Iimpawu zale meko zibandakanya:

• isicaphucaphu okanye ukugabha
• ifiva
• irhashalala
• ukudideka
• igazi kumchamo wakho
• ukudumba
• uxinzelelo lwegazi oluphakamileyo

Ukuba ufumana enye yezi mpawu, biza ugqirha wakho ngoko nangoko. Ukuba iimpawu zakho zibonakala zinzima okanye zisongela ubomi, yiya kwigumbi likaxakeka okanye tsalela umnxeba ku-911.

Izilumkiso zabantu abaneemeko ezithile zempilo

Kubantu abane-osteoporosis: I-Pantoprazole inokunyusa umngcipheko womntu kwi-osteoporosis, imeko ebangela ukuba amathambo aqhekeke. Tshela ugqirha wakho ukuba unembali ye-osteoporosis.

Kubantu abane-magnesium yegazi ephantsi (hypomagnesemia): I-Pantoprazole inganciphisa inani le-magnesium emzimbeni wakho. Tshela ugqirha wakho ukuba unembali yehypomagnesemia.

Kubantu abavavanyelwa i-neuroendocrine tumors: I-Pantoprazole inokubangela iziphumo ezingachanekanga kwezi mvavanyo. Ngesi sizathu, ugqirha wakho uya kuyeka ukuthatha eli chiza ubuncinci kwiintsuku ezili-14 ngaphambi kokuba uvavanywe. Banokuphinda baphinde bavavanye ukuba kufuneka njalo.

Izilumkiso kwamanye amaqela

Abafazi abakhulelweyo: I-Pantoprazole luluhlobo lokukhulelwa lodidi C. Oko kuthetha izinto ezimbini:

1. Ukufundwa kwesiyobisi kwizilwanyana ezikhulelweyo kubonise umngcipheko kwimveku engekazalwa.
2. Akukho zifundo zaneleyo zenziwa kwabasetyhini abakhulelweyo ukubonisa ukuba ichiza libeka umngcipheko kwimveku engekazalwa.

Ukuba ukhulelwe okanye ucwangcisa ukukhulelwa, thetha nogqirha wakho malunga neli chiza.

Kubafazi abancancisayo: I-Pantoprazole inokugqitha kubisi lwebele kwaye ingadluliselwa kusana olusancancisayo. Thetha nomboneleli wakho wezempilo malunga nezinye iindlela zokonyango ngelixa uncancisa.

Kubantwana: Ngamanye amaxesha i-Pantoprazole isetyenziselwa unyango lwexesha elifutshane lokuqaqanjelwa sisisu kubantwana abaneminyaka emi-5 nangaphezulu. Le meko inxulunyaniswa ne-GERD. Kubangela ukucaphuka kunye nokonakalisa umqala kwi-asidi esiswini. Ugqirha womntwana wakho uya kunika idosi echanekileyo.

Uyithatha njani ipantoprazole

Olu lwazi lolawulo lwecwecwe lomlomo le-pantoprazole. Zonke iidosi ezikhoyo kunye neefom azinakufakwa apha. Idosi yakho, ifom, kunye nokuba uyithatha kangaphi kuya kuxhomekeka:

• iminyaka yakho
• imeko inyangwa
• ubuzaza bemeko yakho
• ezinye iimeko zonyango onazo
• usabela njani kwidosi yokuqala

Iifom kunye namandla

Ngokwesiqhelo: IPantoprazole

• Ifom: ithebhulethi yomlomo
• Amandla: 20 mg kunye no-40 mg

Igama lebrand: Protonix

• Ifom: ithebhulethi yomlomo
• Amandla: 20 mg kunye no-40 mg

Umyinge wesifo se-reflux se-gastroesophageal (GERD)

Umthamo wabantu abadala (abaneminyaka eli-18 nangaphezulu)

Umyinge oqhelekileyo: I-40 mg ngosuku, ithathwa kanye ngemini kunye okanye ngaphandle kokutya.

Umthamo womntwana (iminyaka emi-5-17)

• Umyinge oqhelekileyo wabantwana abanobunzima beekhilogram ezingama-40 okanye ngaphezulu: I-40 mg ithathwa kanye ngemini ukuya kuthi ga kwiiveki ezisibhozo.
• Idosi eqhelekileyo yabantwana abanobunzima obuphakathi kwe-15 kunye ne-40 kilogram: I-20 mg ithathwa kanye ngemini ukuya kuthi ga kwiiveki ezisibhozo.

Isisombululo semveliso ye-asidi engaphezulu, njenge-Zollinger-Ellison syndrome

Umthamo wabantu abadala (abaneminyaka eli-18 nangaphezulu)

• Umyinge oqhelekileyo: 40 mg kabini yonke imihla, kunye okanye ngaphandle kokutya.

Umthamo womntwana (iminyaka eyi-0-17 iminyaka)

Idosi ekhuselekileyo nesebenzayo ayimiselwanga abantwana abakule minyaka yobudala.

Iphepha elichazayo ukuba awusenanto oyifunayo: Injongo yethu kukukunika olona lwazi lufanelekileyo nolukhoyo ngoku. Nangona kunjalo, ngenxa yokuba iziyobisi zichaphazela umntu ngamnye ngokwahlukileyo, asinakuqinisekisa ukuba olu luhlu lubandakanya zonke iidosi ezinokubakho. Olu lwazi aluthathi ndawo yengcebiso yezonyango. Soloko uthetha nogqirha wakho okanye usokhemesti malunga needosi ezikulungeleyo.

Thatha njengoko kuyalelwe

Ithebhulethi yomlomo wePantoprazole inokumiselwa ukuba kusetyenziswe ixesha elifutshane okanye ixesha elide. Kuthatha ixesha elingakanani kuya kuxhomekeka kuhlobo nobunzima bemeko yakho. Kuza nomngcipheko omkhulu ukuba awuyithathi njengoko kumiselwe.

Ukuba awuyithathi okanye uyeke ukuyithatha: Ukuba awuthathi iyeza konke konke okanye uyeke ukulithatha, ubeka emngciphekweni ukunciphisa amandla okulawula iimpawu zakho ze-GERD.

Ukuba awuyithathi ngexesha: Ukungathathi i-pantoprazole yonke imihla, ukutsiba iintsuku, okanye ukuthatha amanani ngamaxesha ahlukeneyo emini kunokunciphisa ulawulo lwakho lwe-GERD.

Yintoni omele uyenze xa uphosa idosi: Ukuba uphosa idosi, thatha idosi elandelayo njengoko bekucwangcisiwe. Sukuyiphinda kabini idosi yakho.

Ungaxela njani ukuba ichiza liyasebenza: Unokuxela ukuba i-pantoprazole iyasebenza ukuba iyazinciphisa iimpawu zakho ze-GERD, ezinje:

• isilungulela
• isicaphucaphu
• kunzima ukugwinya
• ukuphinda kwenziwe kwakhona
• uvakalelo lwesigaqa emqaleni wakho

Ukuqwalaselwa okubalulekileyo kokuthatha i-pantoprazole

Gcina ezi ngqwalaselo engqondweni ukuba ugqirha wakho ukumisela ipilisi yepantoprazole yomlomo kuwe.

Ngokubanzi

• Ungayithatha le fomu ngokutya okanye ngaphandle kokutya. Thatha ixesha elifanayo yonke imihla ngemiphumo emihle.
• Musa ukusika, ukutyumza, okanye ukuhlafuna eli yeza.

Ukugcina

• Gcina eli chiza kubushushu begumbi phakathi kwama-68 ° F kunye nama-77 ° F (20 ° C nama-25 ° C).
• Ungayigcina ixeshana elifutshane kumaqondo obushushu asezantsi angama-59 ° F (15 ° C) kwaye aphakamileyo ngama-86 ° F (30 ° C).

Ukuzalisa kwakhona

Umyalelo weli yeza uyaphinda awunyanzelekanga ukuba ufune iphepha elitsha lonyango ukuze uzaliswe kwakhona. Ugqirha wakho uza kubhala inani lezinto ezigcwalisiweyo kugunyaziswe ngugqirha wakho.

Ukubeka iliso kwezonyango

I-Pantoprazole ingathoba amanqanaba e-magnesium kubantu abathile. Ugqirha wakho unokucebisa ukuba kubekwe esweni amanqanaba e-magnesium egazi xa uphathwa nge-pantoprazole kangangeenyanga ezintathu okanye nangaphezulu.

Ukuhamba

Xa uhamba namayeza akho:

• Soloko uphatha amayeza akho kunye nawe. Xa ubhabha, ungaze uyibeke kwingxowa ekhangelwe. Yigcine kwibhegi yakho yokuqhubela phambili.
• Musa ukuzikhathaza ngoomatshini beX-ray kwisikhululo seenqwelo-moya. Abayi konakalisa amayeza akho.
• Kusenokufuneka ubonise abasebenzi besikhululo seenqwelomoya ilebhile yekhemesti yakho. Soloko uphatha ikhonteyina eneleta emiselweyo yentsusa.
• Musa ukubeka eli yeza kwigumbi leglavu lemoto yakho okanye ulishiye emotweni. Qiniseka ukuthintela ukwenza oku xa imozulu ishushu kakhulu okanye ibanda kakhulu.

Ngaba zikhona ezinye iindlela?

Ezinye iindlela ezinokubakho kwithebhulethi yomlomo zibandakanya:

• Lansoprazole
• ukulele
• omeprazole
• mzwsthi
• mzobozi

Thetha nogqirha wakho ngezinye iindlela zamachiza ezinokusebenzela wena.

Iphepha elichazayo ukuba awusenanto oyifunayo:Iindaba Zonyango Namhlanje wenze yonke imizamo yokuqinisekisa ukuba yonke ingcaciso ichanekile, ibanzi kwaye ihlaziyiwe. Nangona kunjalo, eli nqaku akufuneki lisetyenziswe endaweni yolwazi kunye nobuchule bengcali yezempilo enelayisensi. Kuya kufuneka usoloko uqhagamshelana nogqirha wakho okanye nolunye uqeqesho kwezonyango ngaphambi kokuba uthathe nawaphi na amayeza. Ulwazi lweziyobisi oluqulethwe apha luyakwazi ukutshintsha kwaye alujoliswanga ekusetyenzisweni konke okunokwenzeka, imikhombandlela, izilumkiso, izilumkiso, ukuhlangana kweziyobisi, ukungahambelani komzimba, okanye iziphumo ezibi. Ukungabikho kwezilumkiso okanye olunye ulwazi ngesiyobisi esinikiweyo akubonisi ukuba indibaniselwano yeziyobisi ikhuselekile, iyasebenza, okanye ifanelekile kuzo zonke izigulana okanye konke ukusetyenziswa okuthile.