IPemphigus Foliaceus

Umxholo

• Ziintoni iimpawu?
• Yintoni unobangela?
• Zithini iindlela zokhetho zonyango?
• Zeziphi iingxaki?
• Nini ukubona ugqirha
• Imbonakalo

Ushwankathelo

I-Pemphigus foliaceus sisifo esizimela ngokwaso esibangela ukuba iblisters erhawuzayo yenze ulusu lwakho. Inxalenye yosapho lweemeko ezinqabileyo zolusu ezibizwa ngokuba yi-pemphigus evelisa iblister okanye izilonda kulusu, emlonyeni, okanye kwilungu lobuni.

Zimbini iintlobo eziphambili zepemphigus:

• pemphigus vulgaris
• pemphigus foliaceus

I-Pemphigus vulgaris lolona hlobo luqhelekileyo nolona luqatha. I-Pemphigus vulgaris ayichaphazeli ulusu nje kuphela, kodwa inwebu yangaphakathi. Kubangela ukuba i-blister ebuhlungu ibekho emlonyeni wakho, kulusu lwakho, nakwilungu lakho langasese.

I-Pemphigus foliaceus ibangela i-blisters ezincinci ukuba zenze kwi-torso ephezulu kunye nobuso. Inamandla kune-pemphigus vulgaris.

I-Pemphigus erythematosus luhlobo lwe-pemphigus foliaceus ebangela iblisters ukuba yenze kuphela ebusweni. Ichaphazela abantu abane-lupus.

Ziintoni iimpawu?

I-Pemphigus foliaceus ibangela ukuba i-blisters egcwele ulwelo ifake kulusu lwakho, rhoqo esifubeni, emqolo nasemagxeni. Ekuqaleni amaqamza amancinci, kodwa ayakhula kancinci kwaye anda ngenani. Ekugqibeleni banokugubungela wonke umzimba, ubuso kunye nentloko.

Amadyunguza aqhekeka ngokulula. Ulwelo lunokuvela kubo. Ukuba uhlikihla ulusu lwakho, wonke umaleko ongaphezulu unokwahlula ukusuka ezantsi kamva kwaye uxobule ephepheni.

Emva kokuba i-blister ivulekile, banokwenza izilonda. Izilonda zilinganisela kunye ne-crust over.

Nangona i-pemphigus foliaceus idla ngokungabi buhlungu, unokuziva uqaqanjelwa okanye ukutshiswa kwindawo yamadyungudyungu. Iiblisters nazo zinokukrala.

Yintoni unobangela?

I-Pemphigus foliaceus sisifo sokuzimela. Ngokwesiqhelo, amajoni omzimba akhupha iiproteni ezibizwa ngokuba ngamajoni omzimba ukulwa abahlaseli bamanye amazwe njengeebhaktheriya kunye neentsholongwane. Kubantu abanesifo sokuzimela, ii-antibodies ngempazamo zilandela izicwili zomzimba.

Xa une-pemphigus foliaceus, izilwa-buhlungu zibopha kwiprotein ekwingqimba engaphandle yesikhumba sakho, ebizwa ngokuba yintsholongwane. Kolu luhlu lolusu kukho iiseli ezibizwa ngokuba zii-keratinocytes. Ezi seli zivelisa iprotein-keratin-ebonelela ngolwakhiwo kunye nenkxaso kulusu lwakho. Xa izilwa-buhlungu zihlasela ii-keratinocytes, ziyahlukana.Ulwelo luzalisa izithuba abazishiye ngasemva. Olu lwelo lwenza iblisters.

Oogqirha abazi ukuba yintoni ebangela i-pemphigus foliaceus. Izinto ezimbalwa zinokunyusa amathuba okufumana le meko, kubandakanya:

• ukuba namalungu osapho ane-pemphigus foliaceus
• ukubekwa elangeni
• ukufumana i-insect bite (kumazwe aseMzantsi Melika)

Amachiza aliqela nawo aqhagamshelwe kwi-pemphigus foliaceus, kubandakanya:

• penicillamine (Cuprimine), esetyenziselwa ukunyanga isifo sikaWilson
• i-angiotensin eguqula ii-enzyme inhibitors ezinje nge-captopril (Capoten) kunye ne-enalapril (Vasotec), esetyenziselwa ukunyanga uxinzelelo lwegazi
• ii-angiotensin-II receptor blockers ezinje ngecandesartan (Atacand), esetyenziselwa ukunyanga uxinzelelo lwegazi oluphezulu
• Iintsholongwane ezifana ne-rifampicin (i-Rifadin), esetyenziselwa ukunyanga usulelo lwebacteria
• iziyobisi ezingasebenziyo ezichasayo (ii-NSAID)

I-Pemphigus foliaceus ingaqala nangaliphi na ixesha, kodwa ihlala ichaphazela abantu abaneminyaka engama-50 ukuya kwengama-60. Abantu abangamafa emveli angamaJuda basemngciphekweni omkhulu wepemphigus vulgaris.

Zithini iindlela zokhetho zonyango?

Injongo yonyango kukususa i-blister kunye nokuphilisa i-blisters osele unayo. Ugqirha wakho unokumisela i-corticosteroid cream okanye iipilisi. Eli yeza lizisa ukudumba emzimbeni wakho. Iidosi eziphezulu ze-corticosteroids zinokubangela iziphumo ebezingalindelekanga ezinje ngokunyuka kweswekile yegazi, ukuzuza ubunzima, kunye nelahleko yethambo.

Ezinye iziyobisi ezisetyenziselwa ukunyanga i-pemphigus foliaceus zibandakanya:

• Ukucinezelwa komzimba. Iziyobisi ezinje nge-azathioprine (Imuran) kunye ne-mycophenolate mofetil (CellCept) ithintela amajoni akho omzimba ekuhlaseleni izicwili zomzimba wakho. Iziphumo ebezingalindelekanga eziphambili zezi ziyobisi kukwandisa umngcipheko wosulelo.
• Amayeza okubulala iintsholongwane, amachiza antiviral, kunye namayeza okubulala ukungunda. Oku kunokuthintela amadyungudyungu ukuba angosuleli xa ethe aqhekeka.

Ukuba i-blister igubungela ulusu lwakho oluninzi, kungafuneka uhlale esibhedlele ukuze ufumane unyango. Oogqirha nabongikazi baya kucoca kwaye babophe izilonda zakho ukuthintela usulelo. Unokufumana ulwelo ukuze ubeke endaweni yoko ulahlekelwe zizilonda.

Zeziphi iingxaki?

Amadyungudyungu avulekileyo anokusulelwa ziintsholongwane. Ukuba ibhaktheriya ingena kwigazi lakho, inokubangela usulelo olusongela ubomi olubizwa ngokuba yi-sepsis.

Nini ukubona ugqirha

Jonga ugqirha wakho ukuba une-blisters kulusu lwakho, ngakumbi ukuba ziyavuleka.

Ugqirha wakho uya kubuza malunga neempawu zakho kwaye ahlole ulusu lwakho. Banokususa isiqwenga seethishu kwi-blister kwaye bayithumele kwilebhu yovavanyo. Oku kubizwa ngokuba yi-biopsy yolusu.

Unokuba novavanyo lwegazi ukukhangela izilwa-buhlungu ezenziwa ngamajoni akho omzimba xa une-pemphigus foliaceus.

Ukuba sele ufumene ukuba une-pemphigus, kuya kufuneka unxibelelane nogqirha wakho ukuba uyaphuhlisa:

• amadyunguza amatsha okanye izilonda
• ukusasazeka ngokukhawuleza kwinani lezilonda
• ifiva
• ububomvu okanye ukudumba
• Ukugodola
• ubuthathaka okanye izihlunu eziqaqambayo okanye amalungu

Imbonakalo

Abanye abantu baba ngcono ngaphandle konyango. Abanye banokuhlala nesi sifo iminyaka emininzi. Kuya kufuneka uthathe amayeza iminyaka ukuthintela i-blister ukuba ingabuyi.

Ukuba iyeza libangela i-pemphigus foliaceus, ukumisa iyeza kunokuhlala kusicacisa isifo.