IPolycythemia Vera: Ukuxela kwangaphambili kunye nokuLindelwa koBomi

Umxholo

• Ukuqonda PV
• Ukulawula i-PV
• Ukubeka iliso kwi-PV
• Imbonakalo yePV

IPolycythemia vera (PV) ngumhlaza wegazi onqabileyo. Ngelixa lungekho unyango lwe-PV, inokulawulwa ngonyango, kwaye unokuhlala nesifo iminyaka emininzi.

Ukuqonda PV

I-PV ibangelwa kukutshintsha okanye ukungaqheleki kwimfuza yeeseli zeziqu kumongo wethambo lakho. I-PV iyalenza libe ninzi igazi lakho ngokuvelisa iiseli ezibomvu ezininzi kakhulu, ezinokuthintela ukuhamba kwegazi kumalungu nakwizihlunu.

Oyena nobangela we-PV awaziwa, kodwa kubantu abanalesi sifo banako nokutshintsha kwesifo IJAK2 Uhlobo. Uvavanyo lwegazi lunokufumanisa utshintsho.

I-PV ifunyanwa ikakhulu kubantu abadala. Ayifane yenzeke nakubani na ongaphantsi kweminyaka engama-20.

Phantse abantu aba-2 kwabali-100,000 bachaphazeleka sesi sifo. Kwaba bantu, banokuqhubeka nokukhulisa iingxaki zexesha elide ezinje nge-myelofibrosis (umongo wethambo) kunye neleukemia.

Ukulawula i-PV

Eyona njongo iphambili yonyango kukulawula ukubalwa kweeseli zegazi. Ukunciphisa inani leeseli ezibomvu zegazi kunceda ukuthintela amahlwili anokukhokelela kwistroke, isifo sentliziyo, okanye omnye umonakalo emzimbeni. Kwakhona kunokuthetha ukulawula iiseli ezimhlophe zegazi kunye neeplatelet counts. Inkqubo efanayo ebonakalisa ukuveliswa ngokugqithisileyo kweeseli ezibomvu zegazi ibonakala ngathi ibonisa ukuveliswa okungaphezulu kweeseli ezimhlophe zegazi kunye neeplatelets. Ubalo lweeseli eziphezulu zegazi, nokuba loluphi na uhlobo lweeseli zegazi, lonyusa umngcipheko wamahlwili egazi kunye nezinye iingxaki.

Ngexesha lonyango, ugqirha wakho kuya kufuneka akujonge rhoqo ukuze ubukele i-thrombosis. Oku kwenzeka xa ihlwili legazi likhula emithanjeni okanye emthanjeni kwaye kuthintela ukuhamba kwegazi kumalungu akho amakhulu okanye izicwili.

Ingxaki yexesha elide ye-PV yi-myelofibrosis. Oku kwenzeka xa umongo wethambo lakho unqabile kwaye ungasakwazi ukuvelisa iiseli ezisempilweni ezisebenza ngokufanelekileyo. Wena kunye ne-hematologist yakho (ingcali kwiingxaki zegazi) unokuxoxa ngokufakelwa umongo wethambo kuxhomekeke kwimeko yakho.

Ileukemia yenye ingxaki ye-PV yexesha elide. Ngokukodwa, zombini i-leukemia ye-myeloid (AML) kunye ne-acute lymphoblastic leukemia (ZONKE) zidibene ne-polycythemia vera. I-AML ixhaphake kakhulu. Unokufuna unyango olukhethekileyo olujolise kulawulo lwegazi ukuba le ngxaki iyakhula.

Ukubeka iliso kwi-PV

I-PV inqabile, ke ukubeka esweni rhoqo kunye nokuhlola kubalulekile. Xa ufunyaniswe okokuqala, unokufuna i-hematologist kwiziko lezonyango. Ezi ngcali zegazi ziya kwazi ngakumbi malunga ne-PV. Kwaye kusenokwenzeka ukuba babonelela ngononophelo kumntu onesifo.

Imbonakalo yePV

Nje ukuba ufumane i-hematologist, sebenza nabo ukuseta ishedyuli yokuqeshwa. Ishedyuli yakho yokuqeshwa iya kuxhomekeka kwinkqubela phambili ye-PV yakho. Kodwa kuya kufuneka ulindele ukubona i-hematologist yakho kube kanye ngenyanga ukuya kube kanye kwiinyanga ezintathu kuxhomekeke kubalo lweeseli zegazi, ubudala, impilo iyonke kunye nezinye iimpawu.

Ukubeka iliso rhoqo kunye nokunyanga kunokunceda ukwandisa ixesha lokuphila kunye nokuphucula umgangatho wobomi. Kuxhomekeka kuluhlu olubanzi lwezinto, ixesha lokuphila ngoku libonakalisiwe ukuba lisukela kwixesha lokuchongwa. Ubudala, impilo iyonke, ukubalwa kweeseli zegazi, impendulo kunyango, imfuza, kunye nokukhetha indlela yokuphila, njengokutshaya, zonke zinempembelelo kwisifo kunye nembonakalo yexesha elide.