Umbala weVillonodular Synovitis (PVNS)

Umxholo

• Yintoni ebangela iPVNS?
• Apho emzimbeni ufumaneka khona
• Iimpawu
• Unyango
• Utyando lwearthroscopic
• Utyando oluvulekileyo
• Ukutshintshwa ngokudibeneyo
• Ukulungiswa kwetendon
• Imitha
• Amayeza
• Ixesha lokubuyisela emva kotyando
• Ukulungiswa kwendlela yokuphila
• Yise kude

Ushwankathelo

I-synovium ngumaleko weethambo obeka amalungu. Ikwavelisa ulwelo ukuthambisa amalunga.

Kwi-villonodular synovitis (PVNS) enemibala, i-synovium iyaqina, yenza ukukhula okubizwa ngokuba yithumba.

I-PVNS ayisiwo umhlaza. Ayikwazi ukusasazeka kwamanye amalungu omzimba, kodwa inokukhula iye kwinqanaba apho yonakalisa amathambo akufutshane kwaye ekugqibeleni ibangele isifo samathambo. Ukukhula okungaphezulu komdibaniso odibeneyo kukwabangela iintlungu, ukuqina, kunye nezinye iimpawu.

I-PVNS yinxalenye yeqela lezilonda ezingenamhlaza ezichaphazela amalungu, abizwa ngokuba ziitomosnovial giant cell tumors (TGCTs). Zimbini iintlobo zePVNS:

• Ingingqi okanye i-nodular PVNS ichaphazela indawo enye kuphela yelungu okanye ziithenda ezixhasa ngokudibeneyo.
• Ukusasaza i-PVNS kubandakanya ulungelelwaniso olupheleleyo. Kunganzima ukunyanga kune-PVNS yendawo.

I-PVNS yimeko enqabileyo. Ichaphazela kuphela malunga.

Yintoni ebangela iPVNS?

Oogqirha abazi ukuba yintoni kanye kanye ebangela le meko. Kukho unxibelelwano phakathi kwe-PVNS kunye nokwenzakala kutshanje. Imfuza echaphazela ukukhula kweeseli kwilungu nayo inokudlala indima.

I-PVNS inokuba sisifo esidumbisayo, esifana nesifo samathambo. Ndifumene amanqanaba aphezulu eempawu zokukrala ezinje nge-C-reactive protein (CRP) kubantu abakule meko. Okanye, isenokuphuma ekukhuleni kweseli okungakhange kuhlolwe, okufanayo nomhlaza.

Nangona i-PVNS ingaqala nangaliphi na ixesha, ihlala ichaphazela abantu abakwiminyaka yama-30 nama-40. Abasetyhini kunokwenzeka ukuba bayifumane le meko kunamadoda.

Apho emzimbeni ufumaneka khona

Phantse iipesenti ezingama-80 zexesha, i-PVNS isedolweni. Indawo yesibini exhaphakileyo ngumlenze.

I-PVNS inokuchaphazela:

• igxalaba
• ingqiniba
• isihlahla
• iqatha
• umhlathi (kunqabile)

Kuyinto eqhelekileyo ukuba i-PVNS ibe ngaphezulu kwamalungu omnye.

Iimpawu

Njengoko i-synovium ikhula, ivelisa ukudumba kwilungu. Ukudumba kunokubonakala kumangalisa, kodwa kuhlala kungenabuhlungu.

Ezinye iimpawu zibandakanya:

• ukuqina
• intshukumo encinci kumdibaniso
• ukuphuma, ukutshixa, okanye ukubamba imvakalelo xa ususa ilungu
• ukufudumala okanye ukuthamba ngaphezulu kwendibaniselwano
• ubuthathaka kwilungu

Ezi mpawu zinokubonakala kangangexesha elithile zize zinyamalale. Njengoko isifo siqhubeka, sinokubangela isifo samathambo kwilungu.

Unyango

Ithumba liza kuqhubeka likhula. Ishiye inganyangwa, iya konakalisa ithambo elikufuphi. Olona nyango luphambili lwe-TGCT lityando lokususa ukukhula. Ugqirha lunokwenziwa ngeendlela ezahlukeneyo.

Utyando lwearthroscopic

Le nkqubo incinci ingenayo isebenzisa iindlela ezimbalwa ezincinci. Ugqirha ubeka ubungakanani obucekeceke, obukhanyisiweyo kunye nekhamera ngesinye seziqwenga. Izixhobo ezincinci zingena kwezinye iindawo ezivulekileyo.

Ugqirha uyabona ngaphakathi kwendibaniselwano kwividiyo. Ngexesha lenkqubo, ugqirha wotyando uya kulisusa ithumba kunye neendawo ezonakeleyo zelindle elidibeneyo.

Utyando oluvulekileyo

Ngamanye amaxesha ukusikwa okuncinci akuniki gqirha igumbi elaneleyo lokususa lonke eli thumba. Kule meko, utyando lwenziwa njengenkqubo evulekileyo kusetyenziswa isicatshulwa esinye esikhulu. Oku kuvumela ugqirha ukuba abone sonke isithuba esidibeneyo, esidla ngokufuneka kwizicwili ngaphambili okanye ngasemva kwedolo.

Ngamanye amaxesha, oogqirha basebenzisa indibaniselwano yeendlela ezivulekileyo kunye nearthroscopic kwilungu elinye.

Ukutshintshwa ngokudibeneyo

Ukuba isifo samathambo sonakalise ukudibana okungaphaya kokulungiswa, ugqirha wotyando unokuthi athabathe indawo yonke okanye inxenye yako. Nje ukuba indawo ezonakeleyo zisuswe, kufakwe ezinye endaweni yentsimbi, iplastiki, okanye iiceramic. Izidumba zihlala zingabuyi emva kokudityaniswa ngokudibeneyo.

Ukulungiswa kwetendon

I-PVNS inokulimaza ithenda ngokudibeneyo. Ukuba oku kuyenzeka, unokuba nenkqubo yokuthunga iziphelo zethenda zibuyelane.

Imitha

Utyando alusoloko luphumelela ekususeni lonke ithumba. Abanye abantu abafanelekanga ukuba batyandwe, okanye bakhetha ukungabinayo. Kule meko, i-radiation inokukhetha.

Imitha isebenzisa amaza amandla aphezulu ukutshabalalisa ithumba. Kwixesha elidlulileyo, unyango lwe-radiation luvela kumatshini ongaphandle komzimba.

Ngokwandayo, oogqirha basebenzisa imitha ye-intra-articular, ejoza ulwelo olusasazeka ngemitha kwilungu.

Amayeza

Abaphandi bafunda amachiza ambalwa e-PVNS kuvavanyo lweklinikhi. Iqela leziyobisi zebhayoloji linokunceda ukuthintela iiseli ekuqokeleleni amalungu kunye nokwenza amathumba. La machiza abandakanya:

• ikhampanizumab
• ikwenziwe
• imatinib mesylate (Gleevec)
• I-nilotinib (iTasigna)
• pexidartinib

Ixesha lokubuyisela emva kotyando

Kuthatha ixesha elingakanani ukufumana kwakhona kuxhomekeke kwinkqubo onayo. Kungathatha iinyanga ezimbalwa ukubuyela kwimeko yesiqhelo emva kotyando oluvulekileyo ngokupheleleyo. Ngokwesiqhelo, utyando lwe-arthroscopic lubangela ukubuyisela ixesha ngokukhawuleza kwiiveki ezimbalwa okanye ngaphantsi.

Unyango lomzimba ngundoqo ekuvuseleleni ngokukhawuleza. Ngexesha leeseshoni, uya kufunda imithambo yokuqinisa kunye nokuphucula ukuguquguquka kwindibaniselwano.

Ukulungiswa kwendlela yokuphila

Kubalulekile ukuphumla ngokudibeneyo xa kubuhlungu, nasemva kotyando. Thatha uxinzelelo kumalungu athwele ubunzima njengamadolo kunye nesinqe ngokuhlala ngaphandle kweenyawo zakho kwaye usebenzise iintonga xa uhamba.

Ukuzilolonga rhoqo kunokukunceda ugcine intshukumo ngokudibeneyo kunye nokuthintela ukuqina. Ingcali yonyango ingakubonisa ukuba yeyiphi imithambo ekufuneka uyenzile, kunye nendlela yokwenza ngokukhuselekileyo nangokufanelekileyo.

Ukunciphisa ukudumba kunye nentlungu, bamba iqhwa kumdibaniso ochaphazelekayo imizuzu eli-15 ukuya kwengama-20 ngexesha, amatyeli aliqela ngosuku. Bopha umkhenkce ngetawuli ukuthintela ukutsha kolusu lwakho.

Yise kude

Utyando luhlala luphumelela kakhulu kunyango lwe-PVNS, ngakumbi uhlobo lwasekhaya. Phakathi kweepesenti ezili-10 kunye neepesenti ezingama-30 zamathumba asasazekayo ayakhula emva koqhaqho. Uya kubona ugqirha okunyangayo iminyaka eliqela emva kotyando ukuze aqiniseke ukuba ithumba lakho alikabuyi.