Yintoni i-Red Man Syndrome?

Umxholo

• Iimpawu
• Iifoto zesifo somntu obomvu
• Oonobangela
• Imiba yomngcipheko
• Iziganeko
• Unyango
• Imbonakalo

Ushwankathelo

I-Red man syndrome yeyona nto ixhaphakileyo ekuphenduleni ichiza iVancomycin (Vancocin). Ngamanye amaxesha kubhekiswa njenge-red neck syndrome Igama livela kwi-rash ebomvu ekhulayo ebusweni, entanyeni, kunye nomzimba wabantu abachaphazelekayo.

IVancomycin yintsholongwane. Ihlala isetyenziselwa ukunyanga izifo ezosulelayo zebacteria, kubandakanya ezo zibangelwa yi-staphylococci enganyangekiyo ngemethicillin, ebizwa ngokuba yi-MRSA. Iyeza lithintela ibacteria ekubeni yenze iindonga zeseli, ezibangela ukuba ibacteria ife. Oku kuthintela ukukhula okungaphaya kwaye kunqanda ukusasazeka kosulelo.

IVancomycin inokunikwa nakwiimeko xa umntu eneempawu ezithile zokwaliwa kwezinye iintlobo zeyeza lokubulala iintsholongwane, ezinjengeepenicillin.

Iimpawu

Olona phawu lubalulekileyo lwesifo somntu obomvu kukukhawuleza kobomvu ebusweni, entanyeni, nasemzimbeni ongaphezulu. Ihlala yenzeka ngexesha okanye emva kokufakwa ngaphakathi kwe-intravenous (IV) ye-vancomycin. Kwiimeko ezininzi, ngokukhawuleza iyeza linikezelwa, kokukhona kunokwenzeka ukuba irhashalala livele.

Irhashalala lihlala libonakala kwimizuzu eli-10 ukuya kwengama-30 yonyango lwe-vancomycin. Ukuphendula okulibazisekileyo kuye kwabonwa nakubantu abaye bafumana i-vancomycin infusions iintsuku eziliqela.

Kwiimeko ezininzi, impendulo elandela ukufakwa kwe-vancomycin ithambile kangangokuba inokuthi ingabonakali. Ukuphazamiseka kunye neemvakalelo zokutsha kunye nokurhawuzelela nazo zihlala zibonwa. Ezinye iimpawu eziqhelekileyo kodwa ezinzulu zibandakanya:

• i-hypotension (uxinzelelo lwegazi oluphantsi)
• ukuqhawukelwa ngumphefumlo
• isiyezi
• intloko ebuhlungu
• Ukugodola
• ifiva
• iintlungu zesifuba

Iifoto zesifo somntu obomvu

Oonobangela

Ekuqaleni oogqirha babekholelwa ukuba i-red man syndrome ibangelwa kukungcola kumalungiselelo e-vancomycin. Ngeli xesha, isifo sasidla ngokubizwa ngegama lesidlaliso esithi "iMississippi Mud." Nangona kunjalo, i-red man syndrome iqhubekile ukwenzeka ngaphandle kokuphuculwa okukhulu kokucoceka kwamalungiselelo e-vancomycin.

Ngoku kuyaziwa ukuba i-red man syndrome ibangelwa kukugqithisa kweeseli ezithile zomzimba emzimbeni ukuphendula i-vancomycin. Ezi seli, zibizwa ngokuba ziiseli zemasti, zinxulunyaniswa neempendulo ezingafunekiyo. Xa kugqithisiwe, iiseli zemasti zivelisa izixa ezikhulu zekhompawundi ebizwa ngokuba yi-histamine. Imbali ikhokelela kwiimpawu zesifo somntu obomvu.

Ezinye iintlobo zee-antibiotics, ezifana ne-ciprofloxacin (Cipro), cefepime, kunye ne-rifampin (i-Rimactane, i-Rifadin), inokubangela i-red man syndrome kwiimeko ezinqabileyo.

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Imiba yomngcipheko

Eyona nto iphambili ekuphuhliseni i-red man syndrome kukufumana i-vancomycin infusion ngokukhawuleza. Ukunciphisa umngcipheko wokuba ne-red man syndrome, i-vancomycin kufuneka ilawulwe kancinci kwisithuba seyure enye.

I-Red man syndrome ifunyenwe isenzeka rhoqo kubantu abangaphantsi kweminyaka engama-40, ngakumbi ebantwaneni.

Ukuba ukhe wakha i-red man syndrome ekuphenduleni i-vancomycin, kunokwenzeka ukuba uyakuyihlaziya kwakhona kunyango lwe-vancomycin yexa elizayo. Ubungqongqo beempawu abubonakali buhlukile phakathi kwabantu abaye bafumana i-red man syndrome kwixa elidlulileyo kwaye abantu bayifumana okokuqala.

Iimpawu zesifo somntu obomvu zinokuba mandundu xa unyangwa ngamanye amachiza, anje ngala:

• ezinye iintlobo zee-antibiotics, ezifana ne-ciprofloxacin okanye i-rifampin
• iipilisi zeentlungu ezithile
• izihlunu ezithile zokuphumla

Kungenxa yokuba la machiza anokugqitha kwiiseli zomzimba ezifanayo njenge-vancomycin, ekhokelela ekubeni kubekho impendulo enamandla.

Ixesha elide lokungeniswa kwe-vancomycin linciphisa umngcipheko wokuba ube ne-red man syndrome. Ukuba ngaba unyango lwe-vancomycin luninzi luyafuneka, kufuneka kususwe ukumnika rhoqo kumthamo osezantsi.

Iziganeko

Kukho iingxelo ezahlukeneyo malunga neziganeko zesifo somntu obomvu. Kufunyenwe ukuba kwenzeka naphina ukusuka kwiipesenti ezi-5 ukuya kwezingama-50 zabantu abaphathwe nge-vancomycin esibhedlele. Iimeko ezinobulali kakhulu azinakuhlala zixelwa, ezinokuphendula ngumahluko omkhulu.

Unyango

Irhashalala enxulunyaniswa nesifo somntu obomvu ngokuqhelekileyo livela ngexesha okanye kungekudala emva kokufakwa kwe-vancomycin. Nje ukuba ukukhula kweempawu, isifo somntu obomvu sihlala malunga nemizuzu engama-20. Ngamanye amaxesha, inokuhlala iiyure ezininzi.

Ukuba ufumana i-red man syndrome, ugqirha wakho uza kuyeka unyango lwe-vancomycin kwangoko. Baza kukunika idosi yomlomo ye-antihistamine ukukunceda ukulawula iimpawu zakho. Kwiimeko ezinzima kakhulu, ezifana nezo zibandakanya i-hypotension, unokufuna i-IV fluids, i-corticosteroids, okanye zombini.

Ugqirha wakho uya kulinda iimpawu zakho ziphuculwe ngaphambi kokuba uphinde uqale unyango lwakho lwe-vancomycin. Baza kulawula yonke idosi yakho kwinqanaba elincinci lokunciphisa umngcipheko wokufumana enye impendulo.

Imbonakalo

I-Red man syndrome ihlala yenzeka xa i-vancomycin ifakwa ngokukhawuleza okukhulu, kodwa inokwenzeka xa ichiza linikwa ngezinye iindlela ngokunjalo. Olona phawu luxhaphakileyo kukukhawuleza okubomvu okukhulayo okuphezulu komzimba, kunye nokurhawuzelela okanye ukutshisa.

Iimpawu zesifo somntu obomvu azisoloko zinobuzaza, kodwa zinokungonwabi. Iimpawu zihlala zihlala ixesha elifutshane kwaye zinokulawulwa nge-antihistamines. Ukuba uye wakha i-red man syndrome ngaphambili, kunokwenzeka ukuba uphinde uyihlakulele. Yazisa ugqirha wakho ngaphambi kokufumana ukumiliselwa kwe-vancomycin ukuba ubukhe wanayo le mpendulo kwixa elidlulileyo.