ISimvastatin vs. Atorvastatin: Into ekufuneka uyazi

Umxholo

• Imiphumela
• Intlungu yezihlunu
• Ukudinwa
• Ukukhathazeka esiswini kunye nesifo sohudo
• Isibindi kunye nesifo sezintso
• Ukubetha
• Iswekile yegazi ephezulu kunye neswekile
• Unxibelelwano
• Ukufumaneka kunye neendleko
• Ukuthatha

Malunga nemimiselo

I-Simvastatin (iZocor) kunye ne-atorvastatin (Lipitor) ziindidi ezimbini zeemimiselo onokukuyalelwa ngugqirha wakho. Iingxelo zihlala zimiselwe ukunceda ukunciphisa i-cholesterol yakho. Ngokwe-American College of Cardiology, ii-statins zinokukunceda ukuba:

• une-cholesterol eyongezelelekileyo kwimithambo yakho yegazi
• une-LDL, ekwabizwa ngokuba yi-cholesterol embi, inqanaba elingaphezulu kweemiligram ezili-190 nge-deciliter nganye (mg / dL)
• unesifo seswekile, uphakathi kweminyaka engama-40 ukuya kwengama-75 ubudala, kwaye unenqanaba le-LDL phakathi kwama-70 no-189 mg / dL, nangaphandle kwe-cholesterol kwimithambo yegazi
• une-LDL phakathi kwe-70 mg / dL kunye ne-189 mg / dL, iphakathi kweminyaka engama-40 kunye nama-75 ubudala, kwaye ubuncinci banomngcipheko we-7.5 weepesenti wokuba icholesterol inokwakha kwimithambo yegazi yakho

La machiza ayafana, umahluko omncinci. Jonga indlela abaziqokelela ngayo.

Imiphumela

Zombini i-simvastatin kunye ne-atorvastatin zinokubangela iziphumo ezibi ezahlukeneyo. Ezinye iziphumo ebezingalindelekanga kunokwenzeka ukuba zenzeke nge-simvastatin, kwaye ezinye zinokwenzeka nge-atorvastatin.

Intlungu yezihlunu

Zonke ii-statins zinokubangela iintlungu zemisipha, kodwa esi siphumo sinokubakho ngokusetyenziswa kwe-simvastatin. Intlungu yezihlunu inokukhula kancinci kancinci. Inokuziva ngathi sisihlunu esitshiweyo okanye ukudinwa kwimithambo. Biza ugqirha wakho malunga nayiphi na intlungu onayo xa uqala ukuthatha i-statin, ngakumbi i-simvastatin. Intlungu yezihlunu inokuba luphawu lokuphuhlisa iingxaki zezintso okanye ukonakala.

Ukudinwa

Iziphumo ebezingalindelekanga ezinokubakho nakweliphi na ichiza kukudinwa. Isifundo esixhaswe yi (NIH) ngokuthelekisa ukudinwa kwizigulana ezithathe iidosi ezincinci ze-simvastatin kunye nelinye iyeza elibizwa ngokuba yi-pravastatin. Abafazi, ngakumbi, banomngcipheko wokudinwa ovela kwi-statins, nangona kunjalo ngakumbi kwi-simvastatin.

Ukukhathazeka esiswini kunye nesifo sohudo

Omabini la machiza anokubangela isisu ukuphazamiseka kunye norhudo. Iziphumo ebezingalindelekanga zihlala zisombulula kwiiveki ezimbalwa.

Isibindi kunye nesifo sezintso

Ukuba unesifo sezintso, i-atorvastatin inokuba lukhetho olufanelekileyo kuwe kuba akukho mfuneko yokulungisa idosi. Kwelinye icala, i-simvastatin inokuchaphazela izintso zakho xa unikwa idosi ephezulu (80 mg ngosuku). Ingazicothisa izintso zakho. ISimvastatin nayo iyakha kwinkqubo yakho ekuhambeni kwexesha. Oku kuthetha ukuba ukuba uyithatha ixesha elide, inani leziyobisi kwinkqubo yakho linokongeza. Ugqirha wakho unokuhlengahlengisa idosi yakho.

Nangona kunjalo, ngokusekwe kwiziphumo ezivela kuphononongo luka-2014 olwenziwe ngu, akukho mngcipheko ukonyuka kokulimala kwezintso phakathi kweedosi eziphezulu ze-simvastatin kunye nedosi ephezulu ye-atorvastatin. Ngaphezulu, iidosi ze-simvastatin ezifikelela kuma-80 mg ngosuku aziqhelekanga kakhulu.

Abantu abambalwa abathatha i-statins bahlakulela isifo sesibindi. Ukuba umnyama umchamo okanye iintlungu kwicala lakho ngelixa uthatha ichiza, biza ugqirha ngokukhawuleza.

Ukubetha

Umthamo ophezulu we-atorvastatin (80 mg ngosuku) unxulunyaniswa nomngcipheko ophezulu wokuhlaselwa sisibetho ukuba ubukhe wanesifo esibuhlungu (ischemic stroke) okanye uhlaselo lwexeshana lwe-ischemic (i-TIA, maxa wambi ebizwa ngokuba sisibetho esincinci), kwiinyanga ezintandathu ezidlulileyo.

Iswekile yegazi ephezulu kunye neswekile

Zombini i-simvastatin kunye ne-atorvastatin zinokunyusa iswekile yegazi kunye nomngcipheko wokuba nesifo seswekile. Zonke ii-statins zinokunyusa inqanaba lakho le-hemoglobin A1C, elingumlinganiso wamanqanaba eswekile egazi exesha elide.

Unxibelelwano

Nangona i-grapefruit ingesosisiyobisi, oogqirha bacebisa ukuba ungakuphephi ukutya izixa ezikhulu ze grapefruit okanye ijusi ye grapefruit ukuba uthatha i-statins. Kungenxa yokuba imichiza kwiziqhamo zeediliya inokuphazamisa ukwaphuka kweminye imimiselo emzimbeni wakho. Oku kunokunyusa amanqanaba e-statins egazini lakho kwaye wandise amathuba akho okuba neziphumo ezibi.

Zombini i-simvastatin kunye ne-atorvastatin zinokunxibelelana nezinye iziyobisi. Unokufumana uluhlu oluneenkcukacha zonxibelelwano lwabo kumanqaku e-Healthline kwi-simvastatin nakwi-atorvastatin. Ngokukodwa, i-atorvastatin inokusebenzisana neepilisi zokulawula ukuzalwa.

Ukufumaneka kunye neendleko

Zombini i-simvastatin kunye ne-atorvastatin ziipilisi ezifakwe ifilimu ozithatha ngomlomo, zihlala kanye ngemini. ISimvastatin iza phantsi kwegama iZocor, ngelixa iLipitor ligama legama le-atorvastatin. Nganye iyafumaneka njengemveliso generic, nayo. Ungathenga naliphi na ichiza kwiikhemesti ezininzi ngommiselo kugqirha wakho.

Amachiza ayafumaneka ngala mandla alandelayo:

• I-Simvastatin: 5 mg, 10 mg, 20 mg, 40 mg, kunye ne-80 mg
• I-Atorvastatin: 10 mg, 20 mg, 40 mg, kunye ne-80 mg

Iindleko ze-generic simvastatin kunye ne-atorvastatin zombini ziphantsi ngokufanelekileyo, kwaye i-generic simvastatin ibiza kancinci. Ingena malunga ne- $ 10-15 ngenyanga. I-Atorvastatin ihlala iyi- $ 25-40 ngenyanga.

Amachiza anegama lebrendi abiza kakhulu kuneegeneric. I-Zocor, uphawu lwe-simvastatin, lumalunga ne- $ 200-250 ngenyanga. I-Lipitor, uphawu lwe-atorvastatin, ihlala ikwi- $ 150-200 ngenyanga.

Ke ukuba uthenga i-generic, i-simvastatin yexabiso eliphantsi. Kodwa xa kuziwa kuguqulelo lwamagama egama, i-atorvastatin ayibizi kakhulu.

Ukuthatha

Ugqirha wakho uyakuthathela ingqalelo izinto ezininzi xa ucebisa unyango nge-statin efana ne-simvastatin kunye ne-atorvastatin. Rhoqo, ukukhetha ichiza elifanelekileyo akufani nokuthelekisa amachiza kunye nokunye okunxulumene nokuhlangana okunokwenzeka kunye neziphumo ebezingalindelekanga zembali nganye kwimbali yakho yezonyango kunye nezinye iziyobisi ozithathayo.

Ukuba ngoku uthatha i-simvastatin okanye i-atorvastatin, buza ugqirha wakho le mibuzo ilandelayo:

• Kutheni ndithatha eli chiza?
• Ngaba lisebenza njani eli chiza kum?

Ukuba uneziphumo ebezingalindelekanga njengentlungu yezihlunu okanye umchamo omnyama, thetha nogqirha wakho ngoko nangoko. Nangona kunjalo, ungayeki ukuthatha i-statin yakho ngaphandle kokuthetha nogqirha wakho. Iingxelo zisebenza kuphela ukuba zithathwa yonke imihla.