Iserotonin syndrome: yintoni, iimpawu, izizathu kunye nonyango

Umxholo

• Ziintoni iimpawu
• Izizathu ezinokubangela
• Amayeza anyusa i-serotonin emzimbeni
• Unyango lwenziwa njani

Iserotonin syndrome inokonyuka komsebenzi we-serotonin kwinkqubo ye-nervous system, ebangelwa kukusetyenziswa gwenxa kwamayeza athile, anokuchaphazela ingqondo, izihlunu kunye namalungu omzimba, anokukhokelela ekufeni.

I-Serotonin yi-neurotransmitter esebenza kwingqondo, kubalulekile ekusebenzeni kakuhle komzimba, kuba ilawula imood, ukulala, ukutya, ukubetha kwentliziyo, ubushushu bomzimba kunye nemisebenzi yokuqonda. Nangona kunjalo, iidosi eziphezulu ze-serotonin zinokuhlengahlengisa ukusebenza komzimba kwaye zikhokelele ekubonakaleni kweempawu ezinzima. Bona ngakumbi imisebenzi ye-serotonin.

Unyango lwe-serotonin syndrome kufuneka lwenziwe esibhedlele, ngokukhawuleza, ngokulawulwa kwe-serum emthanjeni, ukumiswa kwamayeza abangele ingxaki kunye nokusetyenziswa kwamachiza ukunciphisa iimpawu.

Ziintoni iimpawu

Ukuxhalaba, ukuba nochuku, ukuphazamiseka kwezihlunu, ukudideka kunye nemibono, ukungcangcazela kunye nokugodola, isicaphucaphu kunye norhudo, ukonyuka koxinzelelo lwegazi kunye nokubetha kwentliziyo, ukunyuka kwengqondo, abafundi abaxubileyo, zezona mpawu zixhaphakileyo.

Kwiimeko ezinzima kakhulu kwaye ukuba ayinyangwa ngokungxamisekileyo, i-serotonin syndrome inokubangela ukuba kubekho iimpawu ezibi kakhulu, ezinje ngokubetha kwentliziyo ngendlela engaqhelekanga, ukulahleka kwengqondo, ukuxhuzula, isiqaqa nokufa.

Izizathu ezinokubangela

Iserotonin syndrome ibangelwa kukusetyenziswa gwenxa kweziyobisi ezonyusa amanqanaba eserotonin emzimbeni. Ke, ukonyusa idosi yamachiza anyusa i-serotonin, indibaniselwano yezi ziyobisi kunye nezinye ezonyusa isenzo sabo, okanye ukusetyenziswa kwala machiza ngaxeshanye namachiza, kunokukhokelela ekuveleni kwesi sifo.

Amayeza anyusa i-serotonin emzimbeni

Amanye amachiza anyusa i-serotonin emzimbeni ngala:

• Ukudakumba, ezinje nge-imipramine, clomipramine, amitriptyline, nortriptyline, fluoxetine, paroxetine, citalopram, sertraline, fluvoxamine, venlafaxine, duloxetine, nefazodone, trazodone, bupropion, mirtazapine, tranylcypromine kunye ne-moclobine.
• Unyango lweMigraine iqela leetriptan, ezinje nge-zolmitriptan, naratriptan okanye sumatriptan, umzekelo;
• Unyango lokukhohlela Eziqulathe i-dextromethorphan, eyinto esebenza kwinkqubo ye-nervous system ukuthintela ukukhohlela;
• Iipioids isetyenziselwa ukunyanga iintlungu, ezinje nge-codeine, morphine, fentanyl, meperidine kunye ne-tramadol, umzekelo;
• Unyango lwesicaphucaphu nokugabha, ezinje nge-metoclopramide kunye ne-ondansetron;
• IiAnticonvulsants, njenge-sodium valproate kunye ne-carbamazepine;
• Iintsholongwane, ii-antifungals kunye ne-antivirals, njenge-erythromycin, i-ciprofloxacin, i-fluconazole kunye ne-ritonavir;
• Iziyobisi ezingekho mthethweni, ezinje ngecocaine, amphetamines, LSD kunye ne-ecstasy.

Ukongeza, ezinye izongezo zendalo, ezinje nge-tryptophan, iSt John's wort (iSt.John's wort) kunye ne-ginseng, xa zidityaniswe ne-anti-depressants, nazo zinokubangela i-serotonin syndrome.

Unyango lwenziwa njani

Unyango lwe-serotonin syndrome luxhomekeke kubukhali beempawu. Kwiimeko ezimodareyithayo ukuya kwezikrakra, kufanele ukuba kwenziwe ngokukhawuleza, esibhedlele, apho umntu abekwe iliso kwaye anokufumana khona i-serum emthanjeni kunye namayeza okunyanga iimpawu, ezinje ngomkhuhlane, ukuphazamiseka kunye nokudumba kwezihlunu, umzekelo. Kwiimeko ezinzima kakhulu, kunokuba yimfuneko ukuthatha amayeza athintela isenzo se-serotonin.

Ukongeza, amayeza umntu awathathayo kufuneka aqwalaselwe kwaye alungiswe ngugqirha, kunye namayeza amiselweyo.