Uvavanyo lweCholinesterase: yintoni, yintoni eyenzelwe yona kwaye iziphumo zithetha ntoni

Umxholo

• Yenzelwe ntoni
• Amaxabiso esalathiso
• Zithetha ntoni iziphumo

Uvavanyo lwe-cholinesterase luvavanyo lwaselebhu oluceliweyo ukuze kuqinisekiswe inqanaba lokuvezwa komntu kwiimveliso eziyityhefu, ezinje ngezibulali zinambuzane, izinambuzane, iyeza lokucoca ukhula okanye isichumiso, umzekelo, ukulungelwa ngakumbi ngabalimi, kuba bahlala benxibelelana iimveliso zezolimo.

I-Cholinesterase yi-enzyme ekhoyo emzimbeni onoxanduva lokuchithwa kwento ebizwa ngokuba yi-acetylcholine, i-neurotransmitter ejongene nokulawula iimpembelelo zemithambo-luvo kwimisipha. Zimbini iindidi ze-cholinesterase:

• I-Erythrocyte cholinesterase, Eqhutywa ziiseli ezibomvu zegazi;
• IPlasma cholinesterase okanye i-serum, eyi-cholinesterase eveliswa sisibindi, iipancreas kunye namathumbu amancinci kwaye ajikeleza kwi-plasma yegazi.

Ukubeka iliso kumanqanaba e-cholinesterase kubalulekile ukuze naluphi na utshintsho lunokuchongwa ngokukhawuleza kwaye lunyangwe, kuthintelwe iingxaki zomntu.

Yenzelwe ntoni

Uvavanyo lwe-cholinesterase luyacetyiswa ngugqirha ikakhulu ukubeka iliso kwinqanaba lokuvezwa kwamafama, umzekelo, kwizibulali zinambuzane nakwizitshabalalisi.

Ukongeza, idosi yale enzyme inokucelwa ukuba ibeke iliso kwizigulana ezinesifo sesibindi, ngakumbi abo bathe bafakelwa ukufakelwa isibindi, njengoko zihlala zinciphile amanqanaba e-cholinesterase.

Umyinge we-cholinesterase ungabonakaliswa kubantu abaneenguqu eziphazamisa ukusebenza ngokuchanekileyo okanye ukuveliswa kwale enzyme.

Amaxabiso esalathiso

Amaxabiso esalathiso sovavanyo lweCholinesterase ayahluka ngokwelabhoratri kunye nekhithi esetyenziselwa ukwenza uvavanyo. Ke, amaxabiso esalathiso aqhelekileyo anokuba phakathi:

• Amadoda: 4620 - 11500 U / L.
• Abafazi: 3930 - 10800 U / L.

Olu vavanyo lwenziwa njengalo naluphi na olunye uvavanyo lwegazi, oko kukuthi, kuqokelelwa isampulu yegazi encinci kwaye ithunyelwe elebhu ukuba ihlalutywe licandelo lebhayoloji. Ngokwelabhoratri kunokucetyiswa ukuba uzile ukutya ubuncinci iiyure ezi-4.

Zithetha ntoni iziphumo

Wena amanqanaba asezantsi I-cholinesterase ikakhulu ibonisa ukuvezwa ixesha elide kwizibulala-zinambuzane ze-organophosphate, eziyizinto ezikhoyo kwi-insecticide, i-pesticides kunye ne-herbicides ekwaziyo ukuthintela ukusebenza kwale enzyme, ekhokelela ekufumaneni i-acetylcholine kwaye enokubangela ukubonakala kweempawu kunye neempawu, ezinje :

• Iicramps;
• Urhudo;
• Ukuphalaza;
• Ukugcwala okugqithisileyo;
• Ubunzima bokubonakalayo;
• Nciphisa uxinzelelo lwegazi;
• Buthathaka kwezihlunu;
• Ukukhubazeka.

Nangona ukwehla kwamanqanaba e-cholinesterase ikakhulu kunxulumene nokunxila, kunokubakho ukwehla kule enzyme kwimeko ye-hepatitis, i-cirrhosis, ukusilela kwentliziyo, isifo esisiso kunye ne-infarction.

Ke ngoko, kubalulekile ukuba iziphumo zovavanyo lwe-cholinesterase zitolikwe kunye neziphumo zezinye iimvavanyo ukuze unobangela wokuhla kwale enzyme uchongwe kwaye kunyango olufanelekileyo kunokuboniswa.

Kwelinye icala, amanqanaba aphezulu I-cholinesterase, ihlala isenzeka ngenxa yokutyeba, isifo seswekile, isifo se-nephrotic kunye ne-hyperthyroidism.