Yintoni ukufakelwa kwesitulo kwaye kwenziwa njani?
Umxholo
- 1. I-Pseudomembranous colitis
- 2. Ukudumba kwesifo
- 3. Isifo esibuhlungu sesisu
- 4. Ukutyeba kakhulu kunye nolunye utshintsho kwimetabolism
- 5. Autism
- 6. Izifo zemithambo-luvo
- Olunye usetyenziso olunokwenzeka
- Ukufakelwa kwakhona kwenziwa njani
Ukutshintshwa kwesitulo luhlobo lonyango oluvumela ukuhanjiswa kwendle isuka komnye umntu esempilweni iye komnye umntu enezifo ezinxulumene namathumbu, ngakumbi kwimeko yesifo sokudumba kwenwebu yengqondo, esibangelwa kukusulelwa ziintsholongwaneIClostridium difficile, kunye nesifo sokukrala kwamathumbu, esifana nesifo sikaCrohn, esisithembiso kunyango lwezinye izifo, ezinje ngesifo samathumbu esikruqulayo, ukutyeba kakhulu kunye ne-autism, umzekelo.
Injongo yokufakelwa kwakhona kwilindle kukulawula i-microbiota yamathumbu, eyiqoqo leebhaktheriya ezingenakubalwa ezihlala ngokwendalo emathunjini. Kubalulekile ukuba le microbiota isempilweni, ngokutya okutyebileyo kwifayibha kunye nokuthintela ukusetyenziswa kwee-antibiotics ngokungeyomfuneko, kuba ayichaphazeli impilo yamathumbu kuphela, kodwa inokuba nefuthe kuphuhliso lwe-immune, metabolic and neurological izifo.
Fumanisa ukuba zeziphi izizathu kunye nendlela onokukuthintela ngayo ukungalingani kwintyatyambo yamathumbu kwi-Intestinal Dysbiosis.
EBrazil, irekhodi lokuqala lofakelo lwelindle lwenziwa ngo-2013, kwisibhedlele i-Israelita Albert Einstein, eSão Paulo. Ukusukela ngoko, kubonisiwe, ngakumbi nangakumbi, ukuba ukufakelwa ilindle kunokuba luncedo kunyango lwezifo ezininzi, ezinje:
1. I-Pseudomembranous colitis
Yeyona nto iphambili ebonisa ukufakelwa yelindle, esibonakala nangokurhala kunye nosulelo wamathumbu yiintsholongwaneIClostridium difficile, Esosulela ikakhulu abantu esibhedlele besebenzisa amayeza okubulala iintsholongwane, njengoko kuthatha ithuba lokususa iintsholongwane ezisempilweni ukuzinza.
Iimpawu eziphambili ze-pseudomembranous colitis ngumkhuhlane, iintlungu zesisu kunye nohudo oluqhubekayo, kwaye unyango lwayo luhlala lwenziwa ngamayeza okubulala iintsholongwane afana neMetronidazole okanye iVancomycin. Nangona kunjalo, kwimeko apho ibhaktiriya inqabileyo, ukufakelwa kwe-fecal kubonakala ukuba kuyasebenza ngokukhawuleza ukulinganisa kwakhona i-flora yamathumbu kunye nokuphelisa isifo.
Fumana iinkcukacha ezithe kratya malunga nokuchongwa kunye nokunyangwa kwesifo sepseudomembranous.
2. Ukudumba kwesifo
Isifo sikaCrohn kunye nokudumba okwenziwa sisilonda sikabhobhosi zezona ndlela ziphambili zesifo sokukrala kwamathumbu, kwaye nangona kungaziwa kakuhle ukuba zibangelwa yintoni, kuyaziwa ukuba, ukongeza kwimpembelelo yamajoni omzimba, kunokubakho isenzo sebhaktiriya esingenampilo emathunjini. kuphuhliso lwezi zifo.
Ke, ukwenza ukufakelwa kwesitulo kunokusebenza ngcono okanye kubangele uxolelo kwisifo sikaCrohn, ngakumbi kwiimeko ezinzima okanye ezinzima zokunyanga.
3. Isifo esibuhlungu sesisu
Isifo sesisu esibuhlungu sibonakala njengezizathu ezininzi, ezinje ngotshintsho kwinkqubo yamathumbu emathunjini, ubuntununtunu bokutya, ufuzo kunye nenqanaba lengqondo, nangona kunjalo, kubonisiwe ukuba, ngakumbi nangakumbi, iintyatyambo zamathumbu zichaphazela ubukho bazo.
Ke, ezinye iimvavanyo zangoku zibonise ukuba ukufakelwa ilindle kuthembisa kakhulu kunyango olusebenzayo lwesi sifo, nangona ezinye iimvavanyo zisafuneka ukuqinisekisa unyango olunokubakho.
4. Ukutyeba kakhulu kunye nolunye utshintsho kwimetabolism
Kuyaziwa ukuba iintyatyambo zamathumbu zingatshintshwa kubantu abatyebe kakhulu, kwaye kukho imiqondiso yokuba ezi bhaktiriya ziguqula indlela umzimba osebenzisa ngayo amandla ekutyeni, kwaye ke, kusenokwenzeka ukuba le isenokuba sesinye sezizathu zobunzima yehla emzimbeni.
Ke ngoko, uphononongo luye lwabona ukuba kunokwenzeka ukunyanga ukutyeba kakhulu kunye nolunye uguquko oluchonga isifo se-metabolic kunye nokufakelwa kwe-fecal, njenge-arterial hypertension, ukumelana ne-insulin, ukonyuka kweglucose egazini, i-cholesterol kunye ne-triglycerides ephezulu, nangona kunjalo kusafuneka. Izifundo zokungqina ukuba olu nyango kufuneka lube njani kwaye luboniswa ngubani.
Ukongeza, kufuneka kukhunjulwe ukuba ukutya okuneswekile kunye namafutha, kunye nefayibha esezantsi, sesinye sezizathu eziphambili zokukhutshwa kweentyatyambo zamathumbu kunye nokusinda kwentsholongwane eyingozi, kwaye, ke, akukho sizathu sokuba ukufakelwa kwe-fecal ukuba akukho kutya kuthabatha ukuhlala kweebhaktiriya ezilungileyo.
5. Autism
Kwaqatshelwa, kuphononongo lwenzululwazi, ukuba abaguli abane-autism abafumene ukufakelwa i-fecal babenokuphucuka kweempawu, nangona kunjalo, ezinye izifundo zisafuneka ukugqiba ukuba kukho ikhonkco kunye nefuthe lale nkqubo kunyango lwe-autism .
6. Izifo zemithambo-luvo
Omnye umsebenzi othembisayo wokumiliselwa kwilindle kukunyanga kunye nokunciphisa iimpawu zezifo zemithambo-luvo ezinjenge-multiple sclerosis, i-myoclonic dystonia kunye nesifo sika-Parkinson, njengoko kuye kwakho unxibelelwano olubalulekileyo phakathi kweentyatyambo zamathumbu kunye nokusebenza komzimba kunye nengqondo.
Olunye usetyenziso olunokwenzeka
Ukongeza kwezi zifo sele zikhankanyiwe, ukufakelwa ilindle kunyango kunye nasekulawuleni ezinye izifo, ezinje ngesifo sesibindi esinganyangekiyo, i-hepatic encephalopathy, izifo ze-immune hematological, ezinje nge-thrombocytopenic purpura, kunye nonyango lwezifo ngokubanzi ezibangelwa ziintsholongwane ezinganyangekiyo.
Ke ngoko, ngaphandle kwonyango lwelindle oluqhutywa iminyaka emininzi kwezonyango, ukufunyanwa kwamandla alo okwenyani kwezempilo kusekutsha, kwaye kunyanzelekile ukuba izifundo zonyango zisangqina zonke ezi zithembiso.
Ukufakelwa kwakhona kwenziwa njani
Ukufakelwa ilindle ngokungenisa ilindle elisempilweni lomnikeli kwisigulana. Ukulungiselela le nto, kufuneka kuqokelelwe malunga ne-50 g yelindle elinikelayo, ekufuneka lihlalutywe ukuqinisekisa ukuba azinayo intsholongwane IClostridium difficile okanye ezinye izifunxi-gazi.
Emva koko, ilindle lihlanjululwe kwityuwa yaza yafakwa emathunjini omguli, ngokusebenzisa ityhubhu ye-nasogastric, i-enema yomqolo, i-endoscopy okanye i-colonoscopy, kunye nethamo elinye okanye nangaphezulu kunokuba yimfuneko, kuxhomekeke kwisifo esinyangiweyo kunye nobukhali bokudumba kwamathumbu.
Inkqubo ihlala ikhawuleza kwaye awuva ntlungu okanye ukungonwabi.