Kutheni iTroponin ibalulekile?

Umxholo

• Amanqanaba aqhelekileyo etroponin
• Ukuphakanyiswa kwetroponin kubangela
• Yintoni onokuyilindela ngexesha lovavanyo
• Imbonakalo

Yintoni iTroponin?

I-Troponins ziiproteni ezifumaneka kwintliziyo kunye nezihlunu zamathambo. Xa intliziyo yonakele, ikhupha itroponin egazini. Oogqirha balinganisa amanqanaba akho e-troponin ukuze abone ukuba uhlangabezana nesifo sentliziyo okanye akunjalo. Olu vavanyo lunokunceda oogqirha ukuba bafumane olona nyango luphambili kwakamsinya.

Ngaphambili, oogqirha basebenzise olunye uvavanyo lwegazi ukukhangela isifo sentliziyo. Oku kwakungasebenzi, nangona kunjalo, kuba iimvavanyo zazingabuthathaka ngokwaneleyo ukuba zibone lonke uhlaselo. Babandakanyeka nezinto ezazingachazanga ngokwaneleyo kwimisipha yentliziyo. Ukuhlaselwa sisifo sentliziyo esincinci akushiye kwanto kuvavanyo lwegazi.

I-Troponin inovakalelo ngakumbi. Ukulinganisa amanqanaba e-troponin yegazi egazini kuvumela oogqirha ukuba bafumane isifo sentliziyo okanye ezinye iimeko ezinxulumene nentliziyo ngokufanelekileyo, kwaye babonelele ngonyango kwangoko.

Iiproteni zeTroponin zahlulahlulwe zangamacandelo amathathu:

• iTroponin C (TnC)
• I-troponin T (TnT)
• troponin I (TnI)

Amanqanaba aqhelekileyo etroponin

Kubantu abasempilweni, amanqanaba e-troponin asezantsi ngokwaneleyo ukuba angabonakali. Ukuba ukhe weva iintlungu zesifuba, kodwa amanqanaba e-troponin asezantsi iiyure ezili-12 emva kokuba iintlungu zesifuba ziqale, ukubakho kokuhlaselwa sisifo sentliziyo ngokungalindelekanga.

Amanqanaba aphezulu etroponin yiflegi ebomvu ebomvu kwangoko. Ukunyuka kwenani, kokukhona i-troponin-ngakumbi i-troponin T kunye nam-ikhutshiwe kwigazi kwaye kokukhona kunokwenzeka ukuba nomonakalo wentliziyo. Amanqanaba eTroponin anokuphakama ngaphakathi kweeyure eziyi-3-4 emva kokuba intliziyo yonakalisiwe kwaye inokuhlala iphezulu ukuya kuthi ga kwiintsuku ezili-14.

Amanqanaba eTroponin alinganiswa kwii-nanograms ngeemililitha. Amanqanaba aqhelekileyo awela ngaphantsi kweepesenti ezingama-99 kuvavanyo lwegazi. Ukuba iziphumo ze-troponin zingaphezulu kweli nqanaba, kunokuba luphawu lomonakalo wentliziyo okanye uhlaselo lwentliziyo. Nangona kunjalo, ucebisa ukuba abantu basetyhini banokufumana ukonzakala kwentliziyo xa behlaselwa sisifo sentliziyo kumanqanaba angaphantsi kwesiqhelo “esiqhelekileyo” esisikiweyo. Oku kuthetha ukuba kwikamva, into ethathwa njengesiqhelo ingahluka kumadoda nabasetyhini.

Ukuphakanyiswa kwetroponin kubangela

Nangona ukunyuka kwamanqanaba e-troponin kuhlala kungumqondiso wokuhlaselwa sisifo sentliziyo, kukho ezinye izizathu zokuba kutheni amanqanaba enokuphakama.

Ezinye izinto ezinokuthi zibe negalelo kumanqanaba aphezulu etroponin zibandakanya:

• umthambo omkhulu
• Ukutsha
• Usulelo olubanzi, njenge-sepsis
• amayeza
• myocarditis, ukudumba kwezihlunu zentliziyo
• i-pericarditis, ukudumba okujikeleze isingxobo sentliziyo
• i-endocarditis, usulelo lwezivalo zentliziyo
• i-cardiomyopathy, intliziyo ebuthathaka
• ukumelwa yintliziyo
• isifo sezintso
• ukubola kwemiphunga, igazi elixineneyo kwimiphunga yakho
• isifo seswekile
• hypothyroidism, idlala lengqula elingasebenziyo
• ukubetha
• ukopha emathunjini

Yintoni onokuyilindela ngexesha lovavanyo

Amanqanaba eTroponin alinganiswa ngokuvavanywa kwegazi okuqhelekileyo. Umboneleli wezempilo uya kuthatha isampuli yegazi lakho kumthambo engalweni okanye esandleni sakho. Unokulindela iintlungu eziphantsi kwaye mhlawumbi ukopha kancinci.

Ugqirha wakho uya kuncoma olu vavanyo ukuba uva iintlungu zesifuba okanye iimpawu ezinxulumene nokuhlaselwa kwentliziyo kubandakanya:

• Intamo, umqolo, ingalo okanye umhlathi
• ukubila kakhulu
• intloko elula
• isiyezi
• isicaphucaphu
• ukuqhawukelwa ngumphefumlo
• ukudinwa

Emva kokuthatha isampulu yegazi, umboneleli wakho wezempilo uya kuvavanya amanqanaba akho etroponin ukufumanisa isifo sentliziyo. Baza kujonga naluphi na utshintsho kwi-electrocardiogram (EKG), ukulandelwa kombane kwentliziyo yakho. Olu vavanyo lunokuphindwa amatyeli aliqela kwithuba leyure ezingama-24 ukukhangela utshintsho. Sebenzisa uvavanyo lwe-troponin kwakamsinya kunokuvelisa into ebubuxoki. Ukunyuka kwamanqanaba etroponin kunokuthatha iiyure ngaphambi kokuba kufumaneke.

Ukuba amanqanaba akho e-troponin aphantsi okanye aqhelekileyo emva kokufumana iintlungu zesifuba, usenokuba awukhe wahlaselwa sisifo sentliziyo. Ukuba amanqanaba akho ayafunyanwa okanye aphezulu, amathuba okonzakala kwentliziyo okanye okuhlaselwa yintliziyo kuphezulu.

Ukongeza ekulinganiseni amanqanaba akho etroponin kunye nokubeka iliso kwi-EKG yakho, umboneleli wakho wezempilo unokufuna ukwenza ezinye iimvavanyo zokuvavanya impilo yakho, kubandakanya:

• iimvavanyo zegazi ezongezelelweyo ukulinganisa amanqanaba e-enzyme yentliziyo
• iimvavanyo zegazi zezinye iimeko zonyango
• i-echocardiogram, i-ultrasound yentliziyo
• iX-reyi yesifuba
• iskena sekhompyuter ye-tomography (CT)

Imbonakalo

I-Troponin yiprotein ekhutshwe egazini lakho emva kokuhlaselwa sisifo sentliziyo. Amanqanaba aphezulu etroponin anokuba zizalathi zezinye iimeko zentliziyo okanye izifo, nazo. Ukuzixilonga akukaze kucetyiswe. Zonke iintlungu zesifuba kufuneka zivavanywe kwigumbi likaxakeka.

Ukuba uqala ukufumana iintlungu esifubeni okanye ukrokrela ukuba unesifo sentliziyo, tsalela umnxeba ku-911. Ukuhlaselwa sisifo sentliziyo kunye nezinye iimeko zentliziyo zinokubulala. Utshintsho kwindlela yokuphila kunye nonyango lunokuphucula impilo yentliziyo kwaye likunikeze umgangatho wobomi ophezulu. Jonga iingcebiso zethu zokugcina intliziyo yakho isempilweni.