Yintoni i-leukocytoclastic vasculitis, oonobangela, iimpawu kunye nonyango

Umxholo

• Oonobangela vasculitis leukocytoclastic
• Iimpawu eziphambili
• Unyango lwenziwa njani

I-leukocytoclastic vasculitis, ekwabizwa ngokuba yi-hypersensitivity vasculitis okanye i-vasculitis encinci yenqanawa, iyahambelana nokudumba kwemithambo yegazi enokuthi yenzeke njengesifo sokudumba, usulelo okanye izifo ezizimele, ezikhokelela ekubonakaleni kwamabala abomvu ikakhulu kwimilenze, emathangeni nakwindawo esiswini.

Ukuchongwa kolu hlobo lwe-vasculitis kwenziwa kuthathelwa ingqalelo iimpawu ezivezwe ngumntu kunye nesiphumo seemvavanyo zaselebhu ezinokucelwa ngugqirha. Kwiimeko ezininzi, iimpawu ze-leukocytoclastic vasculitis ziyanyamalala emva kweenyanga ezimbalwa, nangona kunjalo kunokuba yimfuneko ukusebenzisa amayeza afana ne-antihistamines okanye i-corticosteroids ngokuxhomekeke kubukhali be-vasculitis.

Oonobangela vasculitis leukocytoclastic

Olu hlobo lwe-vasculitis lunokubangelwa zizinto ezininzi kwaye zihlala zinxulumene nezinto ezikhuthaza utshintsho kwinkqubo yomzimba yokuzikhusela. Kungenxa yokuba kukholelwa ukuba iimpawu ze-leukocytoclastic vasculitis zenzeka ngenxa yokusekwa kwamajoni omzimba kwimithambo yegazi encinci, ekhokelela kukudumba.

Ke, oonobangela abaphambili abanxulumene nolu hlobo lwe-vasculitis zezi:

• Ukungezwani komzimba namanye amayeza ezifana ne-antibiotics, i-non-steroidal anti-inflammatory drugs, i-beta-blockers, i-warfarin kunye ne-metformin;
• Ukungezwani komzimba nokunye ukutya okanye izongezo zokutya;
• Usulelo ziibhaktheriya, iintsholongwane okanye izifunxi-gazi, ezona zinto zichaphazeleka rhoqo ezinxulumene noko IStreptococcus pyogenes, Isifo sephepha seMicobacterium, IStaphylococcus aureus, I-Chlamydia trachomatis, I-Neisseria gonorrhoeae, iintsholongwane ze-hepatitis B no-C kunye ne-HIV;
• Izifo ezizenzekelayo ezifana nesifo samathambo, systemic lupus erythematosus kunye nesjogren's syndrome;
• Izifo zesisu ezivuthayo ezifana nesifo sikaCrohn kunye nesilonda esibuhlungu (ulcerative colitis), umzekelo;
• Utshintsho olubi ezinje ngamathumba, i-lymphoma, i-leukemia kunye ne-myelodysplastic syndrome.

Ukuxilongwa kwe-vasculitis ye-leukocytoclastic yenziwa ngugqirha oqhelekileyo, ugqirha we-angiologist, i-rheumatologist okanye i-dermatologist ngovavanyo lokuqala lweempawu kunye neempawu ezibonakaliswa ngumntu. Ukongeza, ugqirha uyacelwa ukuba enze iimvavanyo zaselebhu ezinceda ukwenza uxilongo lokwahlulahlula, njengesixa segazi, i-VSH, iimvavanyo ezivavanya uvavanyo lwesibindi kunye nezintso kunye nomchamo.

Ukuqinisekisa ukuxilongwa, ugqirha ucebisa ukuba kwenziwe i-biopsy yesilonda, ukuze kuvavanyo oluncinci lwethambo lwenziwe, ikakhulu lwenziwa kwiiyure zokuqala ezingama-24 ukuya kuma-48 zokuvela kweempawu neempawu zokuqala. Qonda indlela ekufuneka yenziwe ngayo i-biopsy.

Iimpawu eziphambili

Iimpawu ze-leukocytoclastic vasculitis zinxulumene nokubekwa kwe-immune complexes kwimithambo yegazi, eziyizakhiwo ezakhiwe ngama-antibodies, eziveliswa ngenxa yenkqubo yokuvuvukala, kunye nokujikeleza kwee-antigen. Emva kokusekwa kwezakhiwo zokuzikhusela komzimba kunye nokubekwa emithanjeni, izinto ezinxulumene nomsebenzi wamajoni omzimba ziyasebenza, nto leyo ekhokelela ekubonakaleni kweempawu, eziphambili zezi:

• Ukuvela kwamabala abomvu eluswini;
• Ukutshisa imvakalelo kunye neentlungu kwizilonda;
• Ukurhawuzelela okukhulu;
• Inkangeleko maqhuqhuva;
• Ukuvela kwezilonda eziqhekezayo.

Ezi mpawu zixhaphake kakhulu emilenzeni, emathangeni, ezinqeni nasezantsi esiswini. Ukongeza, kwezona meko zinzima, iimpawu zenkqubo enje ngomkhuhlane, ukwehla kobunzima ngaphandle kwesizathu, iintlungu zemisipha, igazi kumchamo okanye ilindle kunye nokunyusa umthamo wesisu, umzekelo. Kubalulekile kwezi meko ukubonisana nogqirha ukuze uxilongo lwenziwe kwaye kufuneke ukuba kuqalwe kuvavanywa unyango.

Jonga ezinye iimpawu kunye neempawu ze-vasculitis.

Unyango lwenziwa njani

Kwiimeko ezininzi ze-leukocytoclastic vasculitis, iimpawu zihlala zinyamalala ngaphandle kwesidingo sonyango, nangona kunjalo kubalulekile ukuba unobangela uchongwe kuba kunokwenzeka ukuba iindlela zokuthintela isiqendu esitsha se-vasculitis zibonisiwe, njengokumiswa kwamayeza okanye Ukuncipha kokutya kokutya, ukuba i-vasculitis inxulumene nokwaliwa ziziyobisi okanye ukutya, umzekelo.

Ngamanye amaxesha, xa iimpawu zinganyamalali ngexesha okanye xa kuvela iimpawu zenkqubo, ugqirha usenokubonisa ukusetyenziswa kwamayeza athile ukuthintela ukuqhubela phambili kwe-vasculitis kunye nokukhuthaza ukuphuculwa komntu, kwimeko apho ukusetyenziswa kwe-antihistamines okanye i-corticosteroids, ukongeza ekuphumleni nasekuphakamiseni imilenze.