UVincristine: yintoni, iyintoni kunye nemiphumo emibi

Umxholo

• Yenzelwe ntoni
• Kusetyenziswa kwanjani
• Ukungqinelana
• Iziphumo ebezingalindelekanga ezinokwenzeka

UVincristine yinto esebenzayo kwichiza le-antineoplastic eyaziwa njenge-Oncovin, eboniswe kunyango lweentlobo ezahlukeneyo zomhlaza, kubandakanya i-leukemia, imiphunga kunye nomhlaza webele.

Isenzo sayo kukuphazamisa imetabolism yee-amino acid kunye nokuthintela ukwahlulwa kweseli, ukunciphisa ukubanakho komhlaza osasazeka emzimbeni.

Eli yeza liyafumaneka njengenaliti kwaye kufuneka lilawulwe yingcali yokhathalelo lwempilo.

Yenzelwe ntoni

UVincristine sisiyobisi esiboniswe kunyango lwezi ntlobo zilandelayo zomhlaza:

• Leukemia Acute lymphoid;
• Neuroblastoma;
• Ithumba likaWilms;
• Umhlaza webele;
• Umhlaza wemiphunga;
• Umhlaza wesibeleko;
• Umhlaza womlomo wesibeleko;
• Umhlaza womzimba;
• IHodgkin's kunye ne-non-Hodgkin's lymphoma;
• I-sarcoma ka-Ewing;
• Osteosarcoma;
• I-melanoma enobungozi.

Ukongeza, esi sixhobo ikwaboniswa kunyango lwe-mycosis fungoides kunye ne-idiopathic thrombocytopenic purpura. Funda ukuba yintoni kunye nendlela yokuchonga iimpawu ze-idiopathic thrombocytopenic purpura.

Kusetyenziswa kwanjani

Eli yeza kufuneka linikezelwe ngaphakathi ngaphakathi, ligosa lezempilo, kwaye idosi kunye nexesha lonyango kufuneka limiselwe ngugqirha wezomhlaza.

Ngokubanzi, idosi imi ngolu hlobo lulandelayo:

Abantu abadala

• I-0.01 ukuya kwi-0.03 mg yeVincristine ngokwe kg yobunzima bomzimba, njengedosi enye, rhoqo kwiintsuku ezisi-7.

Abantwana

• Ngaphezulu kwe-10 kg: Lawula i-1.5 ukuya kwi-2 mg yeVincristine ngeemitha zesikwere zomhlaba, njengedosi enye, rhoqo kwiintsuku ezisi-7;
• Nge-10 kg okanye ngaphantsi: Lawula i-0.05 mg yeVincristine ngekg yesisindo somzimba, njengedosi enye, rhoqo kwiintsuku ezisi-7.

Ubude bonyango kufuneka buchongwe ngumhlaza.

Ukungqinelana

Eli yeza liyaphikiswa kubantu abane-hypersensitivity kumacandelo efomula nakwizigulana ezinesimo sokudambisa isifo seCharcot-Marie-Tooth syndrome.

Ukongeza, ayifanele isetyenziswe ngabafazi abakhulelweyo kunye nabasetyhini abancancisayo kufuneka bayeke ukuncancisa ngexesha lonyango nge-vincristine.

Iziphumo ebezingalindelekanga ezinokwenzeka

Ezinye zeempembelelo eziqhelekileyo ezinokuthi zenzeke ngexesha lonyango kunye ne-vincristine yilahleko yeenwele, ukuqhina, iintlungu zomzimba, ukwehla kweeseli ezimhlophe zegazi, ukuphulukana nemvakalelo, ukuhamba nzima kunye nokulahleka kwengqondo.

Iziphumo ebezingalindelekanga ezimandundu ezinokubakho kukuphazamiseka kwemithambo-luvo.