Prurigo Nodularis kunye nolusu lwakho

Umxholo

• Iimpawu
• Imifanekiso
• Unyango
• Iziyobisi ezingundaba-mlonyeni
• Inaliti
• Amayeza enkqubo
• Olunye unyango
• Unyango olutsha
• Izimvo ezingakumbi zokulawula i-PN yakho
• Inkxaso
• Oonobangela
• Iinyani ezikhawulezayo
• Uthintelo
• Ukuthatha

I-Prurigo nodularis (PN) kukungxamiseka okukhulu kolusu. Amagqabantshintshi e-PN eluswini anokuhluka ngokobungakanani ukusuka kwincinci encinci ukuya kwisiqingatha se-intshi ubukhulu. Inani lamaqhuqhuva lingahluka ukusuka ku-2 ukuya ku-200.

Ingcamango eqhelekileyo kukuba kwenzeka ngenxa yokukrwela ulusu. Ulusu olurhawuzayo lunokubakho ngenxa yezizathu ezininzi, ezinje:

• isikhumba esomileyo
• ukungasebenzi kwe-thyroid
• isifo esinganyangekiyo sezintso

Ukurhawuzelelwa kwe-PN kunokuba buthathaka kubukhali bayo. Kucingelwa ukuba kunokuqina okungaphezulu kokurhawuzelela kwayo nayiphi na imeko yolusu ekurhawuzelela.

Ukukhuhla kwenza ukurhawuzelela kube kubi kwaye kunokubangela amaqhuma amaninzi avele kwaye enze mandundu amaqhuma asele ekhona.

I-PN icelomngeni ukunyanga. Makhe sijonge kwiimpawu kunye neendlela zokulawula i-PN.

Iimpawu

I-PN ingaqala njengebhampa encinci, ebomvu ebomvu. Kuvela njengesiphumo sokukrwela ulusu. Amaqhuma aqala ngokuhlala ezingalweni okanye emilenzeni kodwa anokuvela kuwo wonke umzimba wakho, naphi na apho ukrwela khona.

Amaqhuqhuva angarhawuzelela kakhulu. Amaqhuma anokuba:

• nzima
• I-crusty kunye ne-scaly
• Uluhlu lwebala ukusuka kwiithoni zenyama ukuya kwi-pinki, emdaka, okanye emnyama
• ukhwekhwe
• ujonge ujonge

Ulusu oluphakathi kwamaqhuma lunokoma. Abanye abantu abane-PN nabo banamava okutshisa, okuhlaba, kunye neqondo lobushushu kumaqhuma, ngokokuphononongwa ngo-2019.

Amaqhuma anokuhlakulela usulelo lwesibini ukusuka ekukrwemeni rhoqo.

Ukurhawuzelela ngamandla kunokuba buthathaka, kuthintele ukulala ngokuzolileyo kunye nokuphazamisa indlela yakho yemihla ngemihla. Oku kungenza ukuba abantu abane-PN bazive bedandathekile kwaye bedandathekile.

Amaqhuma asombulula ukuba umntu uyeka ukuwakrwela. Banokushiya amanxeba kwezinye iimeko.

Imifanekiso

Unyango

Injongo yonyango lwe-PN kukwaphula umjikelo wokurhawuzelela ngokukhupha ukurhawuzelela.

Umboneleli wakho wezononophelo lwempilo uyakufuna ukunyanga nayiphi na imeko engunobangela wokubamba kunye nokukhuhla.

Unyango oluqhelekileyo lwe-PN lubandakanya zombini iikhrimu kunye neziyobisi zenkqubo yokunceda.

Ngenxa yokuba ukurhawuzelela kunzima kwaye imeko nganye yahlukile, kuya kufuneka uzame uthotho lweendlela ezahlukeneyo zonyango ukuze ufumane eyona isebenza ngcono kuwe.

I-PN sisifo esingafundiswanga.

Kwabanye abantu, akukho sizathu sichongiweyo sokurhawuzelela. Kuba bantu, akukho nonyango olulodwa olusebenzayo.

Okwangoku, iU.S.Ukutya kunye noLawulo lweeDrug (i-FDA) ayikhange ivume naziphi na iindlela zonyango zokunyanga i-PN. Nangona kunjalo, zininzi iziyobisi eziphantsi kophando ezinokuthi zisetyenziswe ngaphandle kwelebheli ukunyanga imeko.

Qiniseka ukuba uxoxa ngemiphumo emibi yamayeza kunye nokusebenzisa amayeza ngaphandle kwelebula kunye nomboneleli wakho wezempilo.

Iziyobisi ezingundaba-mlonyeni

Umboneleli wakho wezempilo unokucebisa malunga ne-counter-counter (i-OTC) okanye amayeza amayeza asemagqabini okuphelisa ukurhawuzelela kunye nokupholisa ulusu lwakho.

Imizekelo inokubandakanya:

• Izihloko ze-steroid ezifana ne-clobetasol okanye i-calcineurin inhibitors ezifana ne-pimecrolimus. (Ezi zinokugutyungelwa ukubanceda ukuba basebenze ngempumelelo ngakumbi.)
• Ingqokelela yamalahle eta
• I-vitamin D-3 yamafutha aqholiweyo (calcipotriol)
• icappsaicin cream
• menthol

Inaliti

Umboneleli wakho wezempilo unokucebisa ngenaliti ye-corticosteroid (Kenalog) yezinye izihlunu.

Amayeza enkqubo

Umboneleli wakho wezempilo unokumisela okanye acebise i-OTC antihistamines ukukunceda ulale ebusuku.

Banokukuyalela amayeza aqhelekileyo asetyenziswa njengezifo zokucinezela ukukunceda uyeke ukukrwela. I-Paroxetine kunye ne-amitriptyline ziye zaphumelela ekuncedeni amaqhuqhuva e-PN ukuba aphucule.

Olunye unyango

Unyango olunokunceda ukunciphisa amaqhuqhuva kunye nokunciphisa ukurhawuzelela kubandakanya:

• ICryotherapy. I-Cryotherapy kukusetyenziswa kwamaqondo obushushu abanda kakhulu kwilonda
• Ifotootherapy. I-Phototherapy isebenzisa ukukhanya kwe-ultraviolet (UV).
• I-Psoralen isetyenziswe ngokudibeneyo ne-UV. I-Psoralen kunye ne-UVA esetyenziswa kunye yaziwa ngokuba yi-PUVA.
• Idayi laser edayiweyo. I-laser yedayi edibeneyo yindlela yonyango esetyenziselwa ukubulala iiseli ezinesifo.
• Unyango lwe-Excimer laser. I-laser ye-excimer kwii-nanometer ezingama-308 ine-PN engazange iphendule kolunye unyango.

Umboneleli wakho wokhathalelo lwempilo usenokucebisa ngonyango lokuguqula umkhuba ukukunceda uyeke ukukrwela.

Unyango olutsha

Ezinye izilingo ezibandakanya ukusebenzisa iziyobisi ngaphandle kwelebheli zibonise isithembiso sokunciphisa ukurhawuzelela.

• I-naloxone efakwe ngaphakathi kunye ne-naltrexone yomlomo kwi-opioid receptor antagonists, enokuba neziphumo ebezingalindelekanga zokuqala
• ii-immunosuppressants, ezibandakanya i-cyclosporine kunye ne-methotrexate
• gabapentinoids, ezisetyenziselwa abantu abangaphenduliyo kwezinye iindlela zonyango okanye abaneeuropathies ezibuhlungu
• I-thalidomide, ebonakalise ukuba iyasebenza, kodwa ithathwa njengeyona ndlela yokugqibela ngenxa yeziphumo ebezingalindelekanga ezinokubakho
• nalbuphine kunye nemolizumab, ngoku ezivavanywa ngoku
• isoquercetin, esisiphumo se-quercetin yesityalo
• , Olu lunyango olutofwayo

Izimvo ezingakumbi zokulawula i-PN yakho

Isikhumba somntu wonke sahlukile, kwaye kungathatha ixesha ukufumana isiqhelo esinceda ukurhawuzelela kwakho.

Indibaniselwano yamayeza inokusebenza ngcono. Kubalulekile ukuzama ukuphula umjikelo wokurhawuzelela ukunqanda amaqhuqhuva ngakumbi kwaye uvumele ezindala ukuba zisombulule.

Ukongeza kumayeza amiselweyo kunye neekhrim ze-OTC:

• Sebenzisa ipakethe yomkhenkce kwindawo ezipholileyo.
• Thatha ubudikidiki, ibhafu emfutshane kunye necolloidal oatmeal.
• Ukuthambisa rhoqo ngeVaselina okanye ukhilimu wehypoallergenic.
• Sebenzisa iisepha ezingenalo ivumba kunye nezinye iimveliso zolusu olubuthathaka.

Inkxaso

Nxibelelana neNodular Prurigo International ngolwazi oluthe kratya okanye ukujoyina iqela labucala le-Facebook okanye uvule iqela le-Facebook.

Ukuthatha inxaxheba kuvavanyo lweklinikhi ye-PN lukhetho.

Oonobangela

Isizathu ngqo se-PN asiqondwa ngokupheleleyo, kodwa izilonda zikholelwa ekubeni ziziphumo ezithe ngqo zesikhumba esirhawuzelelayo, esinokubangelwa zizizathu ezininzi.

I-PN inxulunyaniswa neemeko ezininzi, kubandakanya:

• I-atopic dermatitis (i-eczema)
• isifo seswekile
• ukusilela kwezintso okungapheliyo
• hepatitis C engapheliyo
• ukuphazamiseka kwemithambo-luvo
• ukuphazamiseka kwengqondo
• I-post-herpetic neuralgia
• lymphoma
• ilicus planus
• ukusilela kwentliziyo
• isifo esinganyangekiyo semiphunga (COPD)
• Intsholongwane kaGawulayo
• Amanye amayeza onyango lomhlaza (pembrolizumab, paclitaxel, kunye ne-carboplatin)

Kucingelwa ukuba i-PN yenzeka xa ezinye iimeko zibangela ukurhawuzelela okungapheliyo kunye nokukhuhla (umjikelo wokurhawuzelela), okukhokelela kwizilonda.

Naxa imeko engaphantsi isonjululwe, i-PN kuthiwa ngamanye amaxesha iyaqhubeka.

Kwakhona, isifundo se-2019 siphawula ukuba malunga neepesenti ze-13 zabantu abane-PN abanasifo okanye izinto ezichazayo.

Abaphandi bajonge iindlela ezisisiseko ezichaphazelekayo kwi-PN, ezibandakanya:

• utshintsho kwiiseli zolusu
• imithambo-luvo
• i-neuropeptides kunye neuroimmune system utshintsho

Njengoko unobangela wophuhliso lwe-PN ucaca gca, abaphandi balindele ukuba unyango olungcono luya kubakho.

Iinyani ezikhawulezayo

• I-PN ixhaphake kakhulu kubantu abaphakathi kweminyaka engama-20 nama-60.
• I-PN ichaphazela amadoda nabasetyhini ngokulinganayo.
• I-PN inqabile. Kukho zimbalwa izifundo zokuxhaphaka okanye izehlo. Isifundo se-2018 sezigulana ezingama-909 ezine-PN sifumanise ukuba abaguli base-Afrika baseMelika babeza kuba ne-PN kunezigulana ezimhlophe.

Uthintelo

Kuze kube yinto eyaziwayo ye-PN eyaziwayo, kunzima ukukhusela. Ukungakhangeli ulusu kunokuba kuphela kwendlela.

Ukuba uthambekele kwi-PN, ngenxa yemfuza okanye isifo esisisiseko, jonga ulusu lwakho ngononophelo. Jonga umboneleli wezempilo ukuze anyangwe nakuphi na ukurhawuzelela okuhlala ixesha elide. Zama ukumisa nawuphi na umjikelo wokurhawuzelela ngaphambi kokuba uqale.

Unyango oluninzi lunokunceda ekunciphiseni ukurhawuzelela ngaphambi kokuba kube nzima ukulawula.

Ukuthatha

I-PN yimeko yesikhumba esirhawuzayo enokubangela ukuba kungasebenzi. Isizathu esona ngqo asiqondwa ngokupheleleyo, kodwa kuyaziwa ukuba kunxulunyaniswa nezinye iimeko ezininzi.

Unyango oluninzi lunokwenzeka, kodwa kungathatha ixesha ukulawula ngempumelelo i-PN yakho. Kungenzeka ukuba indibaniselwano yemixholo, iziyobisi, kunye nezinye iindlela zonyango ziya kukusebenzela.

Iindaba ezimnandi zezokuba amachiza amatsha aliqela kunye nonyango ziphantsi kophuhliso kwaye ziyavavanywa. Njengokuba abaphandi befunda okungakumbi malunga nendlela yePN, kuya kujoliswa ngakumbi kunyango olusebenzayo.