Isibindi metastases

I-metastases yesibindi ibhekisa kumhlaza osasazeke esibindini ukusuka kwenye indawo emzimbeni.

I-metastases yesibindi ayifani nomhlaza oqala esibindini, obizwa ngokuba yi-hepatocellular carcinoma.

Phantse nawuphi na umhlaza unganwenwela esibindini. Umhlaza onokusasazeka kwisibindi uquka:

• Umhlaza webele
• Umhlaza womzimba
• Umhlaza wesisu
• Umhlaza wemiphunga
• Melanoma
• Umhlaza wepancreatic
• Umhlaza wesisu

Umngcipheko wokusasazeka komhlaza kwisibindi uxhomekeke kwindawo (indawo) yomhlaza wokuqala. Isifo se-metastasis sesibindi sinokubakho xa kufunyaniswa isifo sokuqala (sokuqala) somhlaza okanye sinokubakho kwiinyanga okanye kwiminyaka emva kokuba kususwe ithumba lokuqala.

Ngamanye amaxesha, akukho zimpawu. Xa iimpawu zivela, zingabandakanya:

• Ukunciphisa ukutya
• Ukudideka
• Umkhuhlane, ukubila
• I-jaundice (ukutyheli kolusu kunye namhlophe ngamehlo)
• Isicaphucaphu
• Intlungu, ihlala ikwindawo ephezulu yesisu
• Ukuhla ukusinda

Iimvavanyo ezinokuthi zenziwe ukuxilonga i-metastases yesibindi zibandakanya:

• Ukuvavanywa kwe-CT kwesisu
• Uvavanyo lomsebenzi wesibindi
• Isibindi se-biopsy
• I-MRI yesisu
• Ukuskena iPET
• I-Ultrasound yesisu

Unyango luxhomekeke:

• Indawo ephambili yomhlaza
• Mangaphi amathumba wesibindi onawo
• Nokuba umhlaza unwenwele kwamanye amalungu
• Impilo yakho iyonke

Iindidi zonyango ezinokusetyenziswa zichaziwe apha ngezantsi.

UKUGQIBELA

Xa ithumba likwindawo enye okanye ezimbalwa zesibindi, umhlaza unokususwa ngotyando.

UKUQINISEKISA

Xa umhlaza usasazekile esibindini nakwamanye amalungu, i-chemotherapy yomzimba wonke (systemic) ihlala isetyenziswa. Uhlobo lwechemotherapy olusetyenzisiweyo luxhomekeke kuhlobo lokuqala lomhlaza.

Xa umhlaza usasazeke esibindini, inkqubo yemichemotherapy isenokusetyenziswa.

I-Chemoembolization luhlobo lwe-chemotherapy kwindawo enye. Umbhobho omncinci obizwa ngokuba yi-catheter ufakwa kwimithambo yegreyini. I-catheter ifakwa kumthambo wesibindi. Iyeza lokubulala umhlaza lithunyelwa nge-catheter. Emva koko elinye iyeza lithunyelwa nge-catheter ukuvimba ukuhamba kwegazi kwinxalenye yesibindi kunye nethumba. Oku "kulamba" iiseli zomhlaza.

OLUNYE UNYANGO

• Utywala (i-ethanol) ingene kwilungu lesibindi-Inaliti ithunyelwa ngesikhumba ngqo kwi-tumor yesibindi. Utywala bubulala iiseli zomhlaza.
• Ubushushu, kusetyenziswa irediyo okanye amandla emicrovesave - Inaliti enkulu ebizwa ngokuba yiprobe ibekwa embindini wethumba lesibindi. Amandla athunyelwa ngocingo olucekeceke olubizwa ngokuba zii-electrode, eziqhotyoshelwe kwiprobe. Iiseli zomhlaza ziyavutha kwaye ziyafa. Le ndlela ibizwa ngokuba yi-radiofrequency ablation xa kusetyenziswa amandla erediyo. Ibizwa ngokuba yi-microwave ablation xa kusetyenziswa amandla e-microwave.
• Ukuqanduselwa, ekwabizwa ngokuba yi-cryotherapy -Probe ibekwe ekunxibelelaneni nethumba. Ikhemikhali ithunyelwa ngeprojekti ebangela ukuba iikristali zomkhenkce zijikeleze iprojekhthi. Iiseli zomhlaza zibandisiwe kwaye ziyafa.
• Amaso erediyo - Le migca ihambisa imitha ukubulala iiseli zomhlaza kwaye ibhloke umthambo oya kwilungu. Le nkqubo ibizwa ngokuba yi-radioembolization. Yenziwe ngendlela efanayo ne-chemoembolization.

Ukwenza kakuhle kangakanani kuxhomekeke kwindawo yomhlaza wokuqala kunye nokuba sele isasazeke njani esibindini okanye naphina. Kwiimeko ezinqabileyo, utyando lokususa amathumba esibindi lukhokelela kunyango. Oku kuhlala kunokwenzeka kuphela xa kukho inani eliqingqiweyo lamathumba esibindini.

Kwiimeko ezininzi, umhlaza osasazeke esibindini awunakuphiliswa. Abantu abanomhlaza onwenwele esibindini bahlala bebulawa sisifo. Nangona kunjalo, unyango lunokunceda ukuncipha amathumba, ukuphucula ixesha lokuphila, kunye nokunciphisa iimpawu.

Iingxaki zihlala ziziphumo zamathumba asasazeka kwindawo enkulu yesibindi.

Banokubandakanya:

• Ukuvalwa kokuhamba kwenyongo
• Ukunciphisa ukutya
• Ifiva
• Ukungaphumeleli kwesibindi (kuhlala kuphela kwinqanaba lesifo)
• Intlungu
• Ukuhla ukusinda

Nabani na onoluhlobo lomhlaza onokuthi usasazeke esibindini kufuneka azi imiqondiso kunye neempawu ezidweliswe apha ngasentla, kwaye ubize ugqirha ukuba kukho enye yezi zinto zikhulayo.

Ukufumanisa kwangoko ezinye iintlobo zomhlaza kunokuthintela ukusasazeka kwale mihlaza kwisibindi.

Metastases kwisibindi; Umhlaza wesibindi; Umhlaza wesibindi - metastatic; Umhlaza womzimba - imastastases yesibindi; Umhlaza Colon - metastases kwesibindi; Umhlaza wokudumba - imastastases yesibindi; Umhlaza wemiphunga - imastastases yesibindi; I-Melanoma - isifo sesibindi

• Isibindi se-biopsy
• Umhlaza we-hepatocellular-CT scan
• Isibindi metastases, CT scan
• Inkqubo yokugaya ukutya

Mahvi DA. Mahvi DM. Isibindi metastases. Ku: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, ii-eds. I-Oncology yeklinikhi yase-Abeloff. Umhla wesi-6. IPhiladelphia, PA: Elsevier; 2020: isahluko 58.