Lactic acidosis

I-Lactic acidosis ibhekisa kwi-lactic acid eyakhayo kwigazi. I-Lactic acid iveliswa xa amanqanaba eoksijini esiba phantsi kwiiseli eziphakathi komzimba apho kwenzeka khona imetabolism.

Unobangela oqhelekileyo we-lactic acidosis sisifo esibuhlungu kwezonyango apho uxinzelelo lwegazi luphantsi kwaye ioksijini encinci kakhulu ifikelela kwizicwili zomzimba. Ukuzivocavoca kakhulu okanye ukuxhuzula kunokubangela okwethutyana kubangele i-lactic acidosis. Izifo ezithile zinokubangela ukuba imeko ibandakanye:

• UGawulayo
• Utywala
• Umhlaza
• Isibindi
• Ityhefu yecyanide
• Ukungaphumeleli kwezintso
• Ukusilela kokuphefumla
• I-Sepsis (isifo esibi)

Amanye amayeza kunqabile ukuba abangele i-lactic acidosis:

• Ezinye i-inhalers zisetyenziselwa ukunyanga i-asthma okanye i-COPD
• Epinephrine
• Iyeza elibizwa ngokuba yi-linezolid
• I-Metformin, esetyenziselwa ukunyanga isifo seswekile (amaxesha amaninzi xa igqithisiwe)
• Uhlobo olunye lwamayeza asetyenziselwa ukunyanga usulelo lwe-HIV
• Ipropol

Iimpawu zingabandakanya:

• Isicaphucaphu
• Ukuhlanza
• Ubuthathaka

Uvavanyo lunokubandakanya uvavanyo lwegazi ukujonga amanqanaba e-lactate kunye ne-electrolyte.

Unyango oluphambili lwe-lactic acidosis kukulungisa ingxaki yezonyango ebangela imeko.

IPalmer BF. I-metosis acidosis. Ku: Feehally J, Floege J, Tonelli, Johnson RJ, ii-eds. I-Clinical Nephrology epheleleyo. Umhla wesi-6. IPhiladelphia, PA: Elsevier; I-2019: isahluko 12.

Seifter JL. Ukuphazamiseka kwesiseko se-Acid. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Umhla wama-25. IPhiladelphia, PA: Elsevier Saunders; 2016: isahl. 118.

Isitshisi RJ. Ukuphazamiseka kwesiseko se-Acid. Ku: Iindonga RM, Hockberger RS, Gausche-Hill M, et al, eds. Unyango lukaRosen oluNgxamisekileyo: Iikhonsepthi kunye nokuziqhelanisa neKlinikhi. Umhla we-9. IPhiladelphia, PA: Elsevier Saunders; I-2018: isahluko 116.