Ihypertriglyceridemia eqhelekileyo

Usapho lwehypertriglyceridemia sisifo esiqhelekileyo esidluliswa ziintsapho. Ibanga inqanaba eliphezulu kuneliqhelekileyo le-triglycerides (uhlobo lwamafutha) egazini lomntu.

Usapho lwehypertriglyceridemia ikakhulu lubangelwa sisiphene semfuza esidityaniswe nezinto zokusingqongileyo. Ngenxa yoko, imeko yeqela kwiintsapho. Isifo esiqatha kangakanani na sinokwahluka ngokwesini, ubudala, ukusetyenziswa kwehomoni, kunye nezinto zokutya.

Abantu abanale meko banamanqanaba aphezulu obuphantsi kakhulu be-lipoprotein (VLDL). I-LDL cholesterol kunye ne-HDL cholesterol zihlala ziphantsi.

Kwiimeko ezininzi, usapho lwehypertriglyceridemia alubonakali de kube kwinqanaba lokufikisa okanye ebudaleni. Ukutyeba kakhulu, i-hyperglycemia (amanqanaba aphezulu eglucose egazini), kunye namanqanaba aphezulu e-insulin ahlala ekhona ngokunjalo. Ezi zinto zinokubangela amanqanaba aphezulu e-triglyceride. Utywala, ukutya okuninzi kwii-carbohydrate, kunye nokusetyenziswa kwe-estrogen kunokwenza imeko ibe mandundu.

Kungenzeka ukuba unale meko ukuba unembali yosapho ye-hypertriglyceridemia okanye isifo sentliziyo ngaphambi kweminyaka engama-50.

Awunakuzibona naziphi na iimpawu. Abanye abantu abanesi sifo banokuba nesifo semithambo yegazi besebancinci.

Umboneleli wezempilo uya kwenza uvavanyo lomzimba kwaye abuze malunga nembali yosapho kunye neempawu.

Ukuba unembali yosapho yale meko, kuya kufuneka kuvavanyo lwegazi ukujonga ubuncinci beepoprotein (VLDL) kunye nenqanaba le-triglyceride. Uvavanyo lwegazi luhlala lubonisa ukwanda kancinci kwi-triglycerides (malunga ne-200 ukuya kwi-500 mg / dL).

Iprofayile yomngcipheko wecoronary nayo inokwenziwa.

Injongo yonyango kukulawula iimeko ezinokuphakamisa amanqanaba e-triglyceride. Oku kubandakanya ukutyeba kakhulu, i-hypothyroidism, kunye neswekile.

Umboneleli wakho unokukuxelela ukuba ungaseli utywala. Ezinye iipilisi zokulawula ukuzalwa zingaphakamisa amanqanaba e-triglyceride. Thetha nomboneleli wakho malunga nomngcipheko wakho xa usenza isigqibo sokuba uthathe la mayeza.

Unyango lukwabandakanya ukuphepha iikhalori ezigqithisileyo kunye nokutya okunamafutha amaninzi kunye neecarbohydrate.

Kuya kufuneka uthathe amayeza ukuba amanqanaba akho e-triglyceride ahlala ephezulu nasemva kokwenza utshintsho kwindlela otya ngayo. I-Nicotinic acid, gemfibrozil, kunye ne-fenofibrate ibonakalisiwe kumanqanaba asezantsi e-triglyceride kubantu abakule meko.

Ukunciphisa umzimba kunye nokugcina isifo seswekile kulawulo kunceda ekuphuculeni iziphumo.

Iingxaki zinokubandakanya:

• Ipancreatitis
• Imithambo yegazi

Ukuvavanya amalungu osapho kwi-triglycerides ephezulu kunokubhaqa esi sifo kwangoko.

Uhlobo lwe-IV hyperlipoproteinemia

• Ukutya okusempilweni

UGenest J, uLibby P.Lipoprotein ukuphazamiseka kunye nesifo sentliziyo. Ku: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, ii-eds. Isifo sentliziyo seBraunwald: Incwadi yesifundo seMpilo yeNtliziyo. Ngomhla we-11. IPhiladelphia, PA: Elsevier; I-2019: isahluko 48.

URobinson JG. Ukuphazamiseka kwemetabolism yelipid. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Ngomhla wama-26. IPhiladelphia, PA: Elsevier; 2020: isahl. 195.