I-nephritis yangaphakathi

I-nephritis yangaphakathi kukuphazamiseka kwezintso apho izithuba eziphakathi kweetyhubhu zezintso ziye zidumbe (zitshise). Oku kunokubangela iingxaki ngendlela ezisebenza ngayo izintso zakho.

I-nephritis yangaphakathi inokuba yeyethutyana (i-acute), okanye ingahlala ixesha elide (engapheliyo) kwaye ibe mandundu ngokuhamba kwexesha.

Ifomu etsolo ye nephritis zangaphakathi idla ngokubangelwa ziziphumo ebezingalindelekanga ezithile iziyobisi.

Oku kulandelayo kunokubangela i-nephritis engaphakathi:

• Ukusabela komzimba kumayeza (i-acute interstitial allergic nephritis).
• Iziphazamiso ze-autoimmune, ezinje ngesifo se-membrane esingaphantsi kwe-antitubular, isifo seKawasaki, isifo seSjögren, inkqubo ye-lupus erythematosus, okanye i-granulomatosis ene-polyangiitis.
• Usulelo.
• Ukusetyenziswa kwexesha elide kwamayeza afana ne-acetaminophen (iTylenol), i-aspirin, kunye ne-nonsteroidal anti-inflammatory drug (NSAIDs). Oku kubizwa ngokuba yi-analgesic nephropathy.
• Iziphumo ebezingalindelekanga ze-antibiotics ezinje nge-penicillin, ampicillin, methicillin, kunye ne-sulfonamide amayeza.
• Iziphumo ebezingalindelekanga zamanye amayeza afana ne-furosemide, thiazide diuretics, omeprazole, triamterene, kunye ne-allopurinol.
• I-potassium encinci egazini lakho.
• I-calcium eninzi okanye i-uric acid egazini lakho.

I-nephritis yangaphakathi inokubangela iingxaki ezinobunzima kwizintso, kubandakanya ukusilela kwezintso. Malunga nesiqingatha samatyala, abantu baya kunciphisa ukuphuma komchamo kunye neminye imiqondiso yokusilela kwezintso.

Iimpawu zale meko zinokubandakanya:

• Igazi kumchamo
• Ifiva
• Ukonyuka okanye ukunciphisa imveliso yomchamo
• Ukutshintsha kwemeko yengqondo (ukozela, ukudideka, isiqaqa)
• Isicaphucaphu, ukugabha
• Irhashalala
• Ukudumba kwayo nayiphi na indawo yomzimba
• Ukutyeba (ukusuka ekugcineni ulwelo)

Umboneleli wezempilo uya kwenza uvavanyo lomzimba. Oku kunokutyhila:

• Umphunga ongaqhelekanga okanye izandi zentliziyo
• Igazi elonyukayo
• Ulwelo kwimiphunga (i-edema yemiphunga)

Uvavanyo oluqhelekileyo lubandakanya:

• Iigesi zegazi
• Ikhemesti yegazi
• I-BUN kunye nenqanaba lokudala kwegazi
• Gcwalisa ubalo lwegazi
• Isifo sezintso
• Isifo sezintso
• Uhlalutyo lomchamo

Unyango luxhomekeke kwisizathu sengxaki. Ukuphepha amayeza akhokelela kule meko kunokususa ngokukhawuleza iimpawu.

Ukunciphisa umda ityuwa kunye nolwelo ekudleni kunokuphucula ukudumba kunye noxinzelelo lwegazi oluphezulu. Ukunciphisa umda kwiprotheyini ekutyeni kunokunceda ukulawula ukwakhiwa kweemveliso zenkunkuma egazini (azotemia), ezinokuthi zikhokelele kwiimpawu zokungaphumeleli kwezintso.

Ukuba i-dialysis iyimfuneko, ihlala ifuneka ixesha elifutshane kuphela.

ICorticosteroids okanye amayeza anamandla okulwa nokudumba anjenge-cyclophosphamide ngamanye amaxesha anokuba luncedo.

Rhoqo, i-nephritis yangaphakathi kukuphazamiseka okwethutyana. Kwiimeko ezinqabileyo, inokubangela umonakalo osisigxina, kubandakanya ukusilela kwezintso ixesha elide (ezingapheliyo).

I-nephritis yesiqhelo ye-interstitial inokuba nzima kakhulu kwaye inakho ukukhokelela ekonakaleni kwexesha elide okanye okusisigxina kubantu abadala.

I-Metabolic acidosis inokwenzeka ngenxa yokuba izintso azikwazi ukususa i-asidi eyaneleyo. Esi sifo sinokukhokelela ekusileleni kwezintso ezibi okanye ezingapheliyo okanye isifo sesifo sokugqibela.

Fowunela umnikezeli wakho ukuba unempawu ze-nephritis yangaphakathi.

Ukuba une-nephritis yangaphakathi, biza umnikezeli wakho ukuba ufumana iimpawu ezintsha, ngakumbi ukuba awuphaphile okanye unokwehla kwimveliso yomchamo.

Rhoqo, ukuphazamiseka akunakuthintelwa. Ukuphepha okanye ukunciphisa ukusebenzisa kwakho amayeza anokubangela le meko kunokunceda ukunciphisa umngcipheko. Ukuba kukho imfuneko, umboneleli wakho uya kukuxelela ukuba ngawaphi amayeza onokuwayeka okanye uwaphule.

Nephritis yetubulointerstitial; I-Nephritis - indawo; Zangaphakathi Acute (negazi) nephritis

• I-anatomy yezintso

UNeilson EG. I-nephritis yetubulointerstitial. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Umhla wama-25. IPhiladelphia, PA: Elsevier Saunders; I-2016: isahluko 122.

IPerazella MA, iRosner MH. Izifo ze-tubulointerstitial. Ku: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, ii-eds. Brenner kunye noMphathi weZintso. Ngomhla we-10. IPhiladelphia, PA: Elsevier; 2020: isahluko 35.

UTanaka T, uNangaku M. I-nephritis engapheliyo. Ku: Feehally J, Floege J, Tonelli M, Johnson RJ, ii-eds. I-Clinical Nephrology epheleleyo. Umhla wesi-6. IPhiladelphia, PA: Elsevier; I-2019: isahluko 62.