I-Poststreptococcal glomerulonephritis (i-GN)

I-Poststreptococcal glomerulonephritis (GN) sisifo sezintso esenzeka emva kosulelo kwiintlobo ezithile zebacteria ye-streptococcus.

I-Poststreptococcal GN luhlobo lwe-glomerulonephritis. Kubangelwa usulelo ngohlobo lwe-streptococcus bacteria. Usulelo alwenzeki kwizintso, kodwa kwindawo eyahlukileyo yomzimba, efana nolusu okanye umqala. Ingxaki inokukhula kwiiveki ezi-1 ukuya kwezi-2 emva kokusuleleka kwintsholongwane yomlomo, okanye kwiiveki ezi-3 ukuya kwezi-4 emva kokusuleleka kwesikhumba.

Inokwenzeka kubantu bayo nayiphi na iminyaka, kodwa ihlala ixhaphaka kubantwana abaneminyaka emi-6 ukuya kweli-10. Nangona ulusu kunye nomqala usulelo luxhaphakile ebantwaneni, i-poststreptococcal GN ayifane ibe yingxaki yezi zifo. I-Poststreptococcal GN ibangela ukuba imithambo yegazi encinci kwiiyunithi zokucoca zezintso (glomeruli) zitshise. Oku kwenza ukuba izintso zingakwazi ukuhluza umchamo.

Le meko ayiqhelekanga namhlanje kuba usulelo olunokukhokelela kwisifo luyanyangwa ngamayeza okubulala iintsholongwane.

Izinto zomngcipheko zibandakanya:

• Umqalaizitrephi zomqala
• Usulelo lwe-Streptococcal lolusu (njenge-impetigo)

Iimpawu zinokubandakanya nayiphi na kwezi zinto zilandelayo:

• Ukuncipha kwemveliso yomchamo
• Umchamo wombala wokurusa
• Ukudumba (ukudumba), ukudumba ngokubanzi, ukudumba kwesisu, ukudumba kobuso okanye kwamehlo, ukudumba kweenyawo, amaqatha, izandla
• Igazi elibonakalayo kumchamo
• Intlungu edibeneyo
• Ukuqina ngokudibeneyo okanye ukudumba

Uvavanyo lomzimba lubonisa ukudumba (i-edema), ngakumbi ebusweni. Izandi ezingaqhelekanga zinokuviwa xa umamele intliziyo kunye nemiphunga ngestethoscope. Uxinzelelo lwegazi luhlala luphezulu.

Olunye uvavanyo olunokwenziwa lunokubandakanya:

• Umchasi-DNase B
• ISerum ASO (kunye ne-streptolysin O)
• Amanqanaba okuncedisa weSerum
• Uhlalutyo lomchamo
• I-biopsy yezintso (ihlala ingafuneki)

Akukho lunyango oluthile kwesi sifo. Unyango lujolise ekunciphiseni iimpawu.

• Amayeza okubulala iintsholongwane, afana nepenicillin, aya kuthi asetyenziselwe ukutshabalalisa nayiphi na ibhaktiriya ye-streptococcal eseleyo emzimbeni.
• Amayeza oxinzelelo lwegazi kunye neziyobisi ezichazayo zinokufuneka ukulawula ukudumba kunye noxinzelelo lwegazi.
• ICorticosteroids kunye namanye amayeza alwa nokudumba awasebenzi.

Kuya kufuneka unciphise ityuwa ekudleni kwakho ukulawula ukudumba kunye noxinzelelo lwegazi.

I-Poststreptococcal GN ihlala ihamba ngokwayo emva kweeveki ezininzi ukuya kwiinyanga.

Kwinani elincinci labantu abadala, kunokuba kubi ngakumbi kwaye kukhokelele kukusilela kwezintso ixesha elide (ezingapheliyo). Ngamanye amaxesha, inokuqhubela phambili ukuya kwinqanaba lesifo sezintso, esifuna i-dialysis kunye nokufakelwa kwezintso.

Iingxaki zempilo ezinokubangelwa sesi sifo zibandakanya:

• Ukungasebenzi kakuhle kwezintso (ukulahleka okukhawulezileyo kwezintso 'ukususa inkunkuma kunye nokunceda ulungelelwaniso lwamanzi kunye neelectrolyte emzimbeni)
• I-glomerulonephritis engapheliyo
• Isifo sezintso esinganyangekiyo
• Ukungaphumeleli kwentliziyo okanye i-edema yemiphunga (i-fluid buildup kwimiphunga)
• Isifo se-renal sokugqibela
• Hyperkalemia (inqanaba eliphezulu le potassium egazini)
• Uxinzelelo lwegazi (uxinzelelo lwegazi)
• I-Nephrotic syndrome (iqela leempawu ezibandakanya iprotheni kumchamo, amanqanaba amancinci eprotini egazini, amanqanaba aphezulu e-cholesterol, amanqanaba aphezulu e-triglyceride, kunye nokudumba)

Fowunela umboneleli wakho wezempilo ukuba:

• Unempawu ze-poststreptococcal GN
• Une-poststreptococcal GN, kwaye unciphise ukuphuma komchamo okanye ezinye iimpawu ezintsha

Ukunyanga izifo ezaziwayo ze-streptococcal kunokunceda ukuthintela i-poststreptococcal GN. Ukwenza ucoceko olufanelekileyo njengokuhlamba izandla kuhlala kuthintela ukusasazeka kwesifo.

Glomerulonephritis - poststreptococcal; I-glomerulonephritis yesifo esosulelayo

• I-anatomy yezintso
• IGlomerulus kunye nephron

Umgangatho FX. Izifo ezingafaniyo ze-glomerular ezinxulunyaniswa ne-hematuria ephezulu ephindaphindayo. Ku: Kliegman RM, St Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, ii-eds. Incwadi kaNelson yeNcwadi yePediatrics. Umhla wama-21. IPhiladelphia, PA: Elsevier; 2020: isahluko 537.

USaha MK, iPendergraft WF, uJennette JC, uFalk RJ. Isifo esisisiseko se-glomerular. Ku: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, ii-eds. Brenner kunye noMphathi weZintso. Ngomhla we-11. IPhiladelphia, PA: Elsevier; 2020: isahl 31.