Ukusilela kweprotein C okanye uS

Ukusilela kweprotein C okanye i-S kukungabikho kweeprotein C okanye i-S kwindawo egazini yegazi. Iiproteni zizinto zendalo ezinceda ukunqanda amahlwili egazi.

Ukusilela kweprotein C okanye i-S sisifo esifa njengelifa. Oku kuthetha ukuba kudluliswa kwiintsapho. Ukuzalwa kuthetha ukuba ikhona ekuzalweni.

Esi sifo sidala ukujiya kwegazi ngokungaqhelekanga.

Umntu omnye kuma-300 unohlobo olunye oluqhelekileyo kunye noluhlobo olunye olungalunganga lokunqongophala kweprotein C.

Ukusilela kweeprotein S kuncinci kakhulu kwaye kwenzeka malunga nabantu abayi-1 kwabayi-20 000.

Ukuba unale meko, kunokwenzeka ukuba uphuhlise amahlwili egazi. Iimpawu ziyafana ne-vein thrombosis enzulu, kwaye zibandakanya:

• Ubuhlungu okanye ukuthamba kwindawo echaphazelekayo
• Ububomvu okanye ukudumba kwindawo echaphazelekayo

Umboneleli wezempilo uya kwenza uvavanyo lomzimba kwaye abuze malunga nembali yakho yonyango kunye neempawu.

Iimvavanyo zaselebhu ziya kwenziwa ukukhangela iiproteni C kunye no-S.

Iziyobisi ezinciphisa igazi zisetyenziselwa ukunyanga nokukhusela amahlwili egazi.

Isiphumo sihlala silungile kunyango, kodwa iimpawu zinokubuya, ngakumbi ukuba iiarhente zokucoca igazi ziyekwe.

Iingxaki zinokubandakanya:

• Ukubethwa komntwana
• Ukulahleka kokukhulelwa okungaphezulu kwesinye (ukuphuma kwesisu kwakhona)
• Amahlwili aphindaphindeneyo emithanjeni
• I-pulmonary embolism (i-clot yegazi kwimithambo yamaphaphu)

Kwiimeko ezinqabileyo, ukusebenzisa i-warfarin ukuthoba igazi kunye nokuthintela amahlwili kunokubangela ukonyuka okufutshane kunye nokulimala kolusu. Abantu basemngciphekweni ukuba abanyangwa nge-heparin yegazi ecothayo ngaphambi kokuthatha i-warfarin.

Fowunela umnikezeli wakho ukuba uneempawu zokujiyiswa kwemithambo (ukudumba nobomvu bomlenze).

Ukuba umboneleli wakho ukufumanisa ukuba unale ngxaki, kuya kufuneka ulumkele ukuthintela amahlwili ekwenzeni. Oku kunokwenzeka xa igazi lihamba kancinci emithanjeni, njengokuphumla ebhedini ixesha elide ngexesha lokugula, utyando, okanye ukuhlala esibhedlele. Inokwenzeka kwakhona emva kwendiza ende okanye uhambo lwemoto.

Ukusilela kweeproteni; Ukusilela kweProteni C

• Ukubumba kwegazi
• Amahlwili egazi

UAnderson JA, uHogg KE, uWeitz JI. Amazwe angenakuchaphazeleka. Ku: Hoffman R, Benz EJ, Silberstein LE, et al, ii-eds. I-Hematology: Imigaqo esisiseko kunye nokuziqhelanisa. Umhla wesi-7. IPhiladelphia, PA: Elsevier; I-2018: isahluko 140.

IPatterson JW. Ipateni yokuphendula ye-vasculopathic. Ku: Patterson JW, ed. Weedon's Ulusu lwezifo. Ngomhla we-4. IPhiladelphia, PA: Elsevier; 2015: isahl 8.