Iindidi zonyango lwehomoni

Unyango lwehormone (HT) lusebenzisa enye okanye nangakumbi iihomoni ukunyanga iimpawu zokuyeka ukuya exesheni. I-HT isebenzisa i-estrogen, iprogestin (uhlobo lweprogesterone), okanye zombini. Ngamanye amaxesha i-testosterone iyongezwa.

Iimpawu zokuyeka ukuya exesheni zibandakanya:

• Kushushu
• Ukubila ebusuku
• Iingxaki zokulala
• Ukoma kwelungu lobufazi
• Ixhala
• Ukuziphatha
• Umdla omncinci kwisini

Emva kokuyeka ukuya exesheni, umzimba wakho uyayeka ukwenza i-estrogen kunye neprogesterone. I-HT inokunyanga iimpawu zokuyeka ukuya exesheni ezikukhathazayo.

I-HT inobungozi. Inokunyusa umngcipheko wakho:

• Amahlwili egazi
• Umhlaza webele
• Isifo sentliziyo
• Ukubetha
• Amatye egall

Ngaphandle kwezi nkxalabo, kubafazi abaninzi, i-HT yindlela ekhuselekileyo yokunyanga iimpawu zokuyeka ukuya exesheni.

Okwangoku, iingcali azicacanga ukuba ungayithatha ixesha elingakanani i-HT. Amanye amaqela eengcali acebisa ukuba ungathatha i-HT kwiimpawu zokuyeka ukuya exesheni ixesha elide ukuba akukho sizathu sonyango sokuyeka iyeza. Kubafazi abaninzi, iidosi ezisezantsi ze-HT zinokwanela ukulawula iimpawu ezinobunzima. Iidosi ezisezantsi ze-HT zihlala zineziphumo ebezingalindelekanga ezimbalwa. Yonke le micimbi iya kuxoxwa nomboneleli wakho wezempilo.

I-HT iza ngeendlela ezahlukeneyo. Kuya kufuneka uzame iintlobo ezahlukeneyo ngaphambi kokufumana eyona ikusebenzela kakuhle.

I-Estrogen iza:

• Ukutshiza ngeempumlo
• Iipilisi okanye iipilisi, zithathwa ngomlomo
• Ijeli yesikhumba
• Amabala esikhumba, asetyenziswe ethangeni okanye esiswini
• Iikhrim zelungu lobufazi okanye iipilisi zelungu lobufazi ukunceda ukoma kunye neentlungu xa usabelana ngesondo
• Isangqa sangasese

Uninzi lwabasetyhini abathatha i-estrogen kwaye abasenayo isibeleko sabo kufuneka bathathe neprogestin. Ukuthatha zombini iihomoni ngokudibeneyo kunciphisa umngcipheko womhlaza we-endometrial (uterine). Abasetyhini abasuswe isibeleko abanakuwufumana umhlaza we-endometrium. Ke, i-estrogen yodwa iyacetyiswa kubo.

Iprogesterone okanye iprogestin iza:

• Iipilisi
• Amabala esikhumba
• Iikhrim zangasese
• Suppositories lobufazi
• Isixhobo se-intrauterine okanye inkqubo ye-intrauterine

Uhlobo lwe-HT ugqirha wakho oluyalelayo lunokuxhomekeka kwimpawu onazo zokuyeka ukuya exesheni. Umzekelo, iipilisi okanye amabala anokunyanga ukubila ebusuku. Iiringi zangaphantsi, iikhrimu, okanye iipilisi zinceda ekunciphiseni ukoma kwilungu lobufazi.

Xoxa ngezibonelelo kunye nomngcipheko we-HT kunye nomboneleli wakho.

Xa uthatha i-estrogen kunye neprogesterone kunye, ugqirha wakho unokucebisa enye yezi shedyuli zilandelayo:

Unyango lwecyclic hormone ihlala icetyiswa xa uqala ukuya exesheni.

• Uthatha i-estrogen njengepilisi okanye uyisebenzise kwifom yokulungiselela iintsuku ezingama-25.
• Iprogestin yongezwa phakathi kweentsuku ezili-10 ukuya kwezi-14.
• Usebenzisa i-estrogen kunye neprogestin kunye kunye nentsalela yeentsuku ezingama-25.
• Awuthathi naziphi na iihormoni iintsuku ezi-3 ukuya kwezi-5.
• Unokuba nokopha inyanga nenyanga ngonyango olujikelezayo.

Unyango oludibeneyo kuxa uthatha i-estrogen kunye neprogestin kunye yonke imihla.

• Unokuba nokopha okungaqhelekanga xa uqala okanye utshintshela kule shedyuli ye-HT.
• Uninzi lwabasetyhini luyeka ukopha kungaphelanga unyaka.

Ugqirha wakho unokukunika amanye amayeza ukuba uneempawu ezinzima okanye unobungozi obukhulu be-osteoporosis. Umzekelo, unokuthatha i-testosterone, ihomoni eyindoda, ukuphucula ukuqhuba kwakho ngokwesondo.

I-HT inokuba neziphumo ebezingalindelekanga, kubandakanya:

• Ukuqhawula
• Ubunzima besifuba
• Intloko ebuhlungu
• Ukuhamba kweemvakalelo
• Isicaphucaphu
• Ukugcinwa kwamanzi
• Ukopha ngokungaqhelekanga

Tshela ugqirha wakho ukuba ubona iziphumo ebezingalindelekanga. Ukutshintsha idosi okanye uhlobo lwe-HT oluthathayo kunganceda ukunciphisa ezi ziphumo bezingalindelekanga. SUKUYITSHINTSHE idosi yakho okanye uyeke ukuthatha i-HT ngaphambi kokuba uthethe nogqirha wakho.

Ukuba wopha kwilungu lobufazi okanye ezinye iimpawu ezingaqhelekanga ngexesha le-HT, tsalela ugqirha wakho.

Qiniseka ukuba uqhubeka nokubona ugqirha wakho ngokujonga rhoqo xa uthatha i-HT.

Iindidi ze-HRT; Unyango lwe-Estrogen yonyango - iintlobo; I-ERT- iintlobo zonyango lwehomoni; Unyango olubuyisela iHormone - iintlobo; Ukuyeka ukuya exesheni - iintlobo zonyango lwehomoni; Iindidi ze-HT; Iindidi zehomoni zeMenopausal

Uluvo lwekomiti ye-ACOG hayi. 565: Unyango lweHormone kunye nesifo sentliziyo. IGynecol ebambekayo. Ngo-2013; 121 (6): 1407-1410. IINKCUKACHA: 23812486 pubmed.ncbi.nlm.nih.gov/23812486/.

UCosman F, de Beur SJ, LeBoff MS, et al. Isikhokelo sikagqirha kuthintelo kunye nonyango lwe-osteoporosis. Osteoporos Int. Ngo-2014; 25 (10): 2359-2381. IINKCUKACHA: 25182228 pubmed.ncbi.nlm.nih.gov/25182228/.

I-Villiers TJ, iHolo JE, iPinkerton JV, et al. Isiteyitimenti sokuhlaziywa kwemvumelwano kwihlabathi liphela kunyango lwe-menopausal hormone. Ubume bemozulu. Ngo-2016; 19 (4): 313-315. IINKCUKACHA: I-27322027 ipapashwe.ncbi.nlm.nih.gov/27322027/.

Lobo RA. Ukuyeka ukuya exesheni kunye nokhathalelo lomfazi okhulileyo: i-endocrinology, iziphumo zokunqongophala kwe-estrogen, iziphumo zonyango lwehomoni, kunye nezinye iindlela zonyango. Ku: Lobo RA, Gershenson DM, Lentz GM, Valea FA, ii-eds. Gynecology egqibeleleyo. Umhla wesi-7. IPhiladelphia, PA: Elsevier; Ngo-2017: isahluko 14.

UMagowan BA, uOwen P, uThomson A. Ukuyeka ukuya exesheni kunye nonyango lokutshintsha i-hormone. Ku: Magowan BA, Owen P, Thomson A, ii-eds. I-Clinical Obstetrics kunye neGynecology. Ngomhla we-4. Elsevier; I-2019: isahluko 9.

IStuenkel CA, uDavis SR, uGompel A, et al. Unyango lweempawu zokuyeka ukuya exesheni: Isikhokelo sonyango se-Endocrine Society. J Ikliniki ye-Endocrinol Metab. 2015; 100 (11): 3975-4011. IINKCUKACHA: 26444994 pubmed.ncbi.nlm.nih.gov/26444994/.

• Unyango olubuyisela iHormone
• Ukuyeka ukuya exesheni