Neurosyphilis

I-Neurosyphilis sisifo sentsholongwane yobuchopho okanye intambo yomqolo. Ngokuqhelekileyo kwenzeka kubantu abangenayo i-syphilis engaphendulwanga iminyaka emininzi.

I-Neurosyphilis ibangelwa I-Treponema pallidum. Le yintsholongwane ebangela igcushuwa. I-Neurosyphilis ihlala ivela kwisithuba seminyaka eli-10 ukuya kwengama-20 emva kokuba umntu wosulelwe yigcushuwa. Asinguye wonke umntu onegcushuwa ovelisa le ngxaki.

Kukho iindlela ezine ezahlukeneyo ze-neurosyphilis:

• I-Asymptomatic (eyona ndlela iqhelekileyo)
• I-paresis ngokubanzi
• Imeningovascular
• Iithebhu zedorsalis

I-Asymptomatic neurosyphilis yenzeka ngaphambi kwegcushuwa yeempawu. I-Asymptomatic kuthetha ukuba akukho zimpawu.

Iimpawu zihlala zichaphazela inkqubo ye-nervous. Ngokuxhomekeke kwifom ye-neurosyphilis, iimpawu zingabandakanya nayiphi na kwezi zilandelayo:

• Ukuhamba okungaqhelekanga (ukuhamba), okanye ukungakwazi ukuhamba
• Ukuba ndindisholo ezinzwaneni, ezinyaweni okanye emilenzeni
• Iingxaki ngokucinga, ezinje ngokudideka okanye ukugxila okungalunganga
• Iingxaki zengqondo, ezinje ngoxinzelelo okanye ukucaphuka
• Intloko, ukuxhuzula, okanye intamo elukhuni
• Ukuphulukana nolawulo lwesinyi (incontinence)
• Iinyikima, okanye ubuthathaka
• Iingxaki ezibonakalayo, nokuba yimfama

Umboneleli wakho wezempilo uya kuthi enze uvavanyo lomzimba kwaye angafumana oku kulandelayo:

• Ingqondo engaqhelekanga
• Ukubetha kwezihlunu
• Izihlunu zemisipha
• Utshintsho lwengqondo

Uvavanyo lwegazi lunokwenziwa ukufumana izinto eziveliswe yintsholongwane ebangela igcushuwa, oku kubandakanya:

• I-Treponema pallidum I-assay agglutination assay (TPPA)
• Uvavanyo lophando lwesifo seVenereal (VDRL)
• Ukufakwa kwe-Fluorescent treponemal antibody (FTA-ABS)
• Iplasma reagin ekhawulezayo (RPR)

Nge-neurosyphilis, kubalulekile ukuvavanya ulwelo lomqolo kwiimpawu zegcushuwa.

Uvavanyo lokujonga iingxaki kwinkqubo yemithambo-luvo inokubandakanya:

• I-angiogram yeCerebral
• Ukuskena iNtloko ye-CT
• Ukugqobhoza iLumbar (impompo yomqolo) kunye nohlalutyo lwe-cerebrospinal fluid (CSF)
• Ukuskena iMRI kwengqondo, ubuchopho, okanye intambo yomqolo

I-antibiotic penicillin isetyenziselwa ukunyanga i-neurosyphilis. Inokunikwa ngeendlela ezahlukeneyo:

• Ingenwe emthanjeni amatyeli aliqela ngosuku iintsuku ezili-10 ukuya kwezi-14.
• Ngomlomo amaxesha amane ngemini, kudityaniswe ngenaliti yemisipha yemihla ngemihla, yomibini ithathwa kangangeentsuku ezili-10 ukuya kwezi-14.

Kuya kufuneka wenze uvavanyo lwegazi olulandelayo kwi-3, 6, 12, 24, kunye ne-36 yeenyanga ukuqinisekisa ukuba usulelo alusekho. Uya kudinga ukubonwa kwe-lumbar punctures yohlalutyo lwe-CSF rhoqo kwiinyanga ezi-6. Ukuba une-HIV / AIDS okanye enye imeko yonyango, ishedyuli yakho yokulandelelana inokwahluka.

I-Neurosyphilis sisongelo esisongela ubomi segcushuwa. Ukwenza kakuhle kangakanani kuxhomekeke ekubeni yingozi kangakanani na i-neurosyphilis ngaphambi konyango. Injongo yonyango kukuthintela ukonakala ngakumbi. Uninzi lolu tshintsho alunakubuyiselwa umva.

Iimpawu zingangcungcutheka kancinci.

Fowunela umboneleli wakho ukuba une-syphilis kwixa elidlulileyo kwaye ngoku uneempawu zeengxaki zenkqubo ye-neva.

Ukuxilongwa ngokukhawuleza kunye nokunyangwa kwesifo sokuqala segcushuwa kunokuthintela i-neurosyphilis.

I-Syphilis - neurosyphilis

• Inkqubo ye-nervous central kunye ne-peripheral system
• Igcushuwa emva kwexesha

I-Euerle BD. Ukuhlanjwa komqolo kunye novavanyo lwe-cerebrospinal fluid. Ku: Roberts JR, Custalow CB, Thomsen TW, ii-eds. Iinkqubo zeKlinikhi zikaRoberts kunye neHedges kwiNyango kaXakeka kunye noKhathalelo oluQhelekileyo. Umhla wesi-7. IPhiladelphia, PA: Elsevier; I-2019: isahluko 60.

IZiko leLizwe leengxaki zeNeological kunye newebhusayithi yeStroke. Neurosyphilis. www.ninds.nih.gov/Disorders/All-Disorders/Neurosyphilis-Information-Page. Ukuhlaziywa ngo-Matshi 27, 2019. Kufikeleleke ngoFebruwari 19, 2021.

URadolf JD, iTramont EC, uSalazar JC. I-Syphilis (iTreponema pallidum). Ku: Bennett JE, Dolin R, Blaser MJ, ii-eds. Mandell, Douglas, kunye neBennett's Principles and Practice of Infectious Diseases. Umhla we-9. IPhiladelphia, PA: Elsevier; 2020: isahl 237.