I-Niacin yecholesterol

I-Niacin yi-B-vitamin. Xa uthathwa njengommiselo kumayeza amakhulu, unokunceda ukuthoba i-cholesterol kunye namanye amafutha egazini lakho. I-Niacin iyanceda:

• Nyusa i-cholesterol ye-HDL (elungileyo)
• I-LDL engezantsi (embi) ye-cholesterol
• I-triglycerides esezantsi, olunye uhlobo lwamafutha egazini lakho

I-Niacin isebenza ngokuthintela indlela isibindi sakho esenza ngayo i-cholesterol. Ikholesterol inokubambelela kwiindonga zemithambo yakho kwaye icekeceke okanye ibhloke.

Ukuphucula amanqanaba akho e-cholesterol kunokukunceda ukukhusela:

• Isifo sentliziyo
• Ukuhlaselwa yintliziyo
• Ukubetha

Umboneleli wakho wezempilo uya kusebenza nawe ukunciphisa icholesterol ngokuphucula indlela otya ngayo. Ukuba oku akuphumelelanga, amayeza okwehlisa i-cholesterol inokuba linyathelo elilandelayo. Iitatins kucingelwa ukuba zezona ziyobisi zisetyenziswayo kubantu abafuna amayeza ukwehlisa icholesterol yabo.

Uphando ngoku lubonisa ukuba i-niacin ayongezi kwisibonelelo se-statin yodwa yokunciphisa umngcipheko weziganeko zentliziyo, kubandakanya ukubetha kwentliziyo kunye nokubetha.

Ukongeza, i-niacin inokubangela iziphumo ebezingalindelekanga nezinokuba yingozi. Ke ngoko, ukusetyenziswa kwayo kuye kwehla. Nangona kunjalo, abanye abantu banokumiselwa i-niacin ukongeza kwezinye iziyobisi ukuba bane-cholesterol ephezulu kakhulu okanye ukuba abawavumeli amanye amayeza.

Kukho iintlobo ezahlukeneyo zamayeza e-niacin. Uninzi lwezi luza ngendlela engabizi kakhulu, yohlobo oluqhelekileyo.

I-Niacin inokumiselwa kunye namanye amayeza, njenge-statin, ukunceda ukunciphisa i-cholesterol. Iipilisi zokudibanisa ezibandakanya i-nicotinic acid kunye namanye amayeza ayafumaneka.

I-Niacin ikwathengiswa ngaphezulu kwe-counter (i-OTC) njengesongezelelo. Akufanele uthathe i-OTC niacin ukunceda ukunciphisa i-cholesterol. Ukwenza oko kunokuba nemiphumo emibi.

Thatha iyeza lakho njengoko kuyalelwe. Iyeza liza kwifomu yethebhulethi. Musa ukuphula okanye ukuhlafuna iipilisi ngaphambi kokuba uthathe iyeza. Sukuyeka ukuthatha amayeza akho ungakhange uthethe nomboneleli wakho kuqala.

Uthatha i-niacin 1 ukuya kuma-3 amaxesha ngemini. Iza ngamanani ahlukeneyo, kuxhomekeke ekubeni ufuna kangakanani.

Funda ileyibhile ekwibhotile yeepilisi ngocoselelo. Ezinye iimveliso kufuneka zithathwe ngexesha lokulala kunye nokutya okulula, okunamafutha asezantsi; abanye uzobathatha ngesidlo sangokuhlwa. Gwema utywala kunye neziselo ezishushu ngelixa uthatha i-niacin ukunciphisa ukugungxula.

Gcina onke amayeza akho kwindawo epholileyo neyomileyo. Zigcine apho abantwana bengenakufikelela kuzo.

Kuya kufuneka ulandele ukutya okusempilweni ngelixa uthatha i-niacin. Oku kubandakanya ukutya amanqatha amancinci kwisidlo sakho. Ezinye iindlela onokunceda ngazo intliziyo yakho zibandakanya:

• Ukwenza umthambo rhoqo
• Ukulawula uxinzelelo
• Ukuyeka ukutshaya

Ngaphambi kokuba uqale ukuthatha i-niacin, xelela umboneleli wakho ukuba:

• Ngaba ukhulelwe, cwangcisa ukukhulelwa, okanye uncelise
• Unesifo somzimba
• Bathatha amanye amayeza
• Sela utywala kakhulu
• Unesifo seswekile, isifo sezintso, isilonda sephepha, okanye igawuthi

Thetha nomboneleli wakho malunga nawo onke amayeza akho, imifuno, okanye izongezo. Amayeza athile anokusebenzisana ne-niacin.

Uvavanyo lwegazi rhoqo luya kukunceda wena kunye nomboneleli wakho:

• Jonga indlela elisebenza ngayo iyeza
• Ukujonga iziphumo ebezingalindelekanga, ezinjengeengxaki zesibindi

Iziphumo ezinobungozi zingabandakanya:

• Ukugungxula nobomvu ubuso okanye intamo
• Urhudo
• Intloko ebuhlungu
• Isisu esimoshakele
• Ukudumba kolusu

Nangona kunqabile, iziphumo ebezingalindelekanga ezinobuzaza zinokwenzeka. Umboneleli wakho uya kukujonga esweni imiqondiso. Thetha nomboneleli wakho malunga nale ngozi:

• Ukonakala kwesibindi kunye notshintsho kwii-enzyme zesibindi
• Intlungu ebuhlungu yemisipha, ukuthamba, kunye nobuthathaka
• Intliziyo kunye nesingqi sitshintsha
• Utshintsho kuxinzelelo lwegazi
• Ukugungxula ngamandla, irhashalala kunye notshintsho kulusu
• Ukunganyamezelani ngeglucose
• Igawuthi
• Ukuphulukana nombono okanye utshintsho

Kuya kufuneka ubize umnikezeli wakho ukuba uqaphela:

• Iziphumo ebezingalindelekanga ezikukhathazayo
• Ukufa isiqaqa
• Ukuba nesiyezi
• Ukukhawuleza okanye ukungahambi kakuhle kwentliziyo
• Ikhumba eliphuzi okanye amehlo (i-jaundice)
• Ubuhlungu bemisipha kunye nobuthathaka
• Ezinye iimpawu ezintsha

Ummeli we-Antilipemic; Vitamin B3; Nicotinic acid; INiaspan; INiacor; Hyperlipidemia - niacin; Ukuqina kwemithambo - niacin; Icholesterol - niacin; Hypercholesterolemia - niacin; Idyslipidemia - niacin

Iwebhusayithi yeAmerican Heart Association. Amayeza eecholesterol. www.heart.org/en/health-topics/cholesterol/prevention-and-treatment-of-high-cholesterol-hyperlipidemia/cholesterol-medications. Ukuhlaziywa kweyeNkanga 10, 2018. Ifikeleleke ngo-Matshi 4, 2020.

UGenest J, uLibby P.Lipoprotein ukuphazamiseka kunye nesifo sentliziyo. Ku: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, ii-eds. Isifo sentliziyo seBraunwald: Incwadi yesifundo seMpilo yeNtliziyo. Ngomhla we-11. IPhiladelphia, PA: Elsevier; I-2019: isahluko 48.

I-Grundy SM, iLitye NJ, iBaleyy AL, et al. I-2018 AHA / ACC / AACVPR / AAPA / ABC / ACPM / ADA / AGS / APhA / ASPC / NLA / PCNA isikhokelo kulawulo lwe-cholesterol yegazi: ingxelo ye-American College of Cardiology / American Heart Association Task Force kwi-Clinical Practice Guidelines . J NdinguColl Cardiol. 2019; 73 (24): e285 – e350. IINKCUKACHA: 30423393 pubmed.ncbi.nlm.nih.gov/30423393/.

UGuyton JR, uMcGovern ME, uCarlson LA. I-Niacin (nicotinic acid). Ku: IBallantyne CM, ed. I-Clinical Lipidology: Umhlobo kwiBraunwald's Isifo sentliziyo. Ngomhla wesi-2. IPhiladelphia, PA: Elsevier Saunders; 2015: isahluko 24.

Inkulumbuso yaseLavigne, Karas RH. Imeko yangoku ye-niacin kuthintelo lwezifo zentliziyo: uphononongo olucwangcisiweyo kunye nokuhlengahlengiswa kwemeta. J NdinguColl Cardiol. Ngo-2013; 61 (4): 440-446. IINKCUKACHA: 23265337 pubmed.ncbi.nlm.nih.gov/23265337/.

Mani P, Rohatgi A. Unyango lwe-Niacin, i-cholesterol ye-HDL, kunye nesifo sentliziyo: ngaba i-HDL hypothesis ayisebenzi? I-Curr Atheroscler Rep. 2015,17 (8): 43. IINKCUKACHA: 26048725 pubmed.ncbi.nlm.nih.gov/26048725/.

• B Iivithamini
• Icholesterol
• Amayeza eCholesterol
• HDL: "Okulungileyo" iCholesterol
• I-LDL: I-cholesterol "engalunganga"