Umhlaza we-Ovarian

Umhlaza we-Ovarian ngumhlaza oqala kwii-ovari. Ama-ovari ngamalungu obufazi okuzala avelisa amaqanda.

Umhlaza we-Ovarian ngumhlaza wesihlanu oqhelekileyo phakathi kwabasetyhini. Kubangela ukusweleka okungaphezulu kunalo naluphi na olunye uhlobo lomhlaza wabasetyhini.

Unobangela womhlaza wesibeleko awaziwa.

Umngcipheko wokuba nomhlaza we-ovari ubandakanya nayiphi na kwezi zinto zilandelayo:

• Abantwana abambalwa abanomfazi kwaye kamva ebomini uyabeleka, umngcipheko ophakamileyo womhlaza we-ovari.
• Abasetyhini abanomhlaza webele okanye abanembali yosapho yesifo somhlaza webele okanye se-ovari banomngcipheko okhulayo womhlaza we-ovari (ngenxa yeziphene kwimfuza efana ne-BRCA1 okanye i-BRCA2).
• Abasetyhini abathatha indawo ye-estrogen kuphela (hayi ngeprogesterone) kangangeminyaka emi-5 okanye nangaphezulu banokuba semngciphekweni omkhulu womhlaza we-ovari. Iipilisi zolawulo lokuzalwa, nangona kunjalo, zinciphisa umngcipheko womhlaza we-ovari.
• Amayeza okuchuma mhlawumbi awunyusi umngcipheko womhlaza we-ovari.
• Abafazi asebekhulile basemngciphekweni omkhulu wokuba nomhlaza we-ovari. Uninzi lokusweleka komhlaza we-ovari lwenzeka kubafazi abaneminyaka engama-55 nangaphezulu.

Iimpawu zomhlaza we-Ovarian zihlala zingacacanga. Abasetyhini kunye noogqirha babo bahlala betyhola iimpawu kwezinye iimeko eziqhelekileyo. Ngexesha lokufunyanwa komhlaza, ithumba ihlala isasazeka ngaphaya kwama-ovari.

Jonga ugqirha wakho ukuba unempawu ezilandelayo mihla le ngaphezulu kweeveki ezimbalwa:

• Ukudumba okanye ukudumba kwindawo esiswini
• Ubunzima bokutya okanye ukuziva ugcwele ngokukhawuleza (ukusuthisa kwangoko)
• Iintlungu zepelvic okanye zesisu esisezantsi (indawo inokuziva "inzima")
• Umqolo obuhlungu
• I-lymph nodes ezidumbileyo kwi-groin

Ezinye iimpawu ezinokuthi zenzeke:

• Ukukhula kweenwele okugqithileyo okurhabaxa kwaye kumnyama
• Ngokukhawuleza unqwenela ukuchama
• Ukufuna ukuchama rhoqo kunesiqhelo (ukwanda kokuhamba rhoqo komchamo okanye ukungxamiseka)
• Ukuqunjelwa

Uvavanyo lomzimba lungahlala luqhelekileyo. Ngomdlavuza we-ovariji ophambili, ugqirha unokufumana isisu esidumbileyo rhoqo ngenxa yokuqokelelwa kolwelo (ascites).

Uviwo lwe-pelvic lunokutyhila i-ovari okanye isisu esiswini.

Uvavanyo lwegazi lwe-CA-125 aluthathelwa ingqalelo kuvavanyo olulungileyo lokuvavanya umhlaza we-ovari. Kodwa, inokwenziwa ukuba owasetyhini une:

• Iimpawu zomhlaza wesibeleko
• Sele efunyaniswe enomhlaza wesibeleko ukumisela ukuba lusebenza kakuhle kangakanani unyango

Olunye uvavanyo olunokwenziwa lunokubandakanya:

• Gcwalisa inani legazi kunye nekhemistry yegazi
• Uvavanyo lokukhulelwa (i-serum HCG)
• I-CT okanye i-MRI yesinqe okanye isisu
• I-Ultrasound ye-pelvis

Utyando, njenge-laparoscopy okanye i-laparotomy yokuhlola, ihlala isenziwa ukufumana unobangela weempawu. I-biopsy iya kwenziwa ukunceda ukuba ichongwe.

Akukho labhoratri okanye uvavanyo lwe-imaging oluye lwaboniswa ukuba lukwazi ukuvavanya ngempumelelo okanye ukufumanisa umhlaza we-ovari kumanqanaba ayo okuqala, ke akukho luvavanyo luvavanyo lucetyiswayo ngeli xesha.

Utyando lusetyenziselwa ukunyanga onke amanqanaba omhlaza we-ovari. Kumanqanaba okuqala, utyando inokuba kuphela kwonyango olufunekayo. Utyando lunokubandakanya ukususa zombini ii-ovari kunye ne-fallopian tubes, isibeleko, okanye ezinye izinto esiswini okanye esinqeni. Iinjongo zotyando lomhlaza we-ovari zezi:

• Isampula iindawo eziqhelekileyo zokubonakala ukuze ubone ukuba umhlaza usasazekile (isiteji)
• Susa nayiphi na indawo ye-tumor esasazekayo (debulking)

I-Chemotherapy isetyenziswa emva kotyando ukunyanga nawuphi na umhlaza ohleliyo. I-Chemotherapy inokusetyenziswa kwakhona ukuba umhlaza ubuya (ubuyela umva). I-Chemotherapy ihlala inikwa ngaphakathi (nge-IV). Inokujojowe ngqo kwisisu esiswini (i-intraperitoneal, okanye i-IP).

Unyango ngemitha kunqabile ukuba lusetyenziselwe ukunyanga umhlaza we-ovari.

Emva kotyando kunye ne-chemotherapy, landela imiyalelo malunga nokuba kufuneka umbone kangaphi ugqirha kunye neemvavanyo ekufuneka unazo.

Ungaluphelisa uxinzelelo lokugula ngokujoyina iqela lokuxhasa umhlaza. Ukwabelana nabanye abanamava afanayo kunye neengxaki kunokukunceda ungaziva ulilolo.

Umhlaza we-Ovarian awufane ufunyaniswe kwinqanaba lawo lokuqala. Ihlala iqhubela phambili ngokuxilongwa okwenziweyo:

• Phantse isiqingatha sabasetyhini baphila ixesha elide kuneminyaka emi-5 emva kokuxilongwa
• Ukuba isifo senziwe kwangethuba kwesi sifo kwaye unyango lufunyenwe ngaphambi kokuba umhlaza usasazeke ngaphandle kwe-ovary, izinga lokusinda leminyaka emi-5 liphezulu

Nxibelelana nomboneleli wakho wokhathalelo lwempilo ukuba ungumfazi iminyaka engama-40 okanye ngaphezulu ongakhange abe novavanyo lwe-pelvic. Kucetyiswa rhoqo ukuba iimviwo zangasese kubo bonke abantu basetyhini abaneminyaka engama-20 okanye ngaphezulu.

Tsalela umnxeba kwindibano kunye nomboneleli wakho ukuba uneempawu zomhlaza we-ovari.

Akukho zindululo zibekiweyo zokujonga abantu basetyhini ngaphandle kweempawu (asymptomatic) zomhlaza we-ovari. I-pelvic ultrasound okanye uvavanyo lwegazi, olufana ne-CA-125, alufumanekanga lusebenza kwaye alukhuthazwa.

Ukuvavanywa kwemfuza kwe-BRCA1 okanye i-BRCA2, okanye ezinye iintlobo ezinxulumene nomhlaza, kunokucetyiswa kwabasetyhini abasemngciphekweni omkhulu womhlaza we-ovari. Aba ngabafazi abanembali yobuqu okanye yosapho yomhlaza wamabele okanye we-ovari.

Ukususa ii-ovari kunye ne-fallopian tubes kwaye mhlawumbi isibeleko kubafazi abanokungqinisisa kuguquko kwi-BRCA1 okanye i-BRCA2 yemfuza kunokunciphisa umngcipheko wokuba nomhlaza we-ovari. Kodwa, umhlaza we-ovari usenokukhula kwezinye iindawo zepelvis.

Umhlaza - amaqanda

• Imitha esiswini-ukukhutshwa
• I-Chemotherapy -yintoni oza kuyibuza ugqirha wakho
• Imitha yepelvic - ukukhutshwa

• I-anatomy yokuzala yabasetyhini
• I-Ascites ngomhlaza we-ovari-CT scan
• Umhlaza wePeritoneal kunye ne-ovari, CT scan
• Iingozi zomhlaza we-Ovarian
• Iingxaki zokukhula kwe-ovari
• Isibeleko
• Umhlaza we-Ovarian
• Umhlaza we-Ovarian metastasis

UColeman RL, uLiu J, uMatsuo K, uThaker PH, uWestin SN, uSood AK. ICarcinoma yamaqanda kunye neetyhubhu ze-fallopian. Ku: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, ii-eds. I-Oncology yeklinikhi yase-Abeloff. Umhla wesi-6. IPhiladelphia, PA: Elsevier; 2020: isahluko 86.

UColeman RL, uRamirez PT, uGershenson DM. Izifo ze-Neoplastic ze-ovary: ukuhlolwa, i-epithelial enobungozi kunye ne-epithelial ne-germ cell neoplasms, i-sex-cord stromal tumors. Ku: Lobo RA, Gershenson DM, Lentz GM, Valea FA, ii-eds. Gynecology egqibeleleyo. Umhla wesi-7. IPhiladelphia, PA: Elsevier; I-2017: isahluko 33.

Kwiwebhusayithi yeZiko loMhlaza weSizwe. Utshintsho lwe-BRCA: umngcipheko womhlaza kunye novavanyo lwemfuzo. www.cancer.gov/about-cancer/causes-prevention/genetics/brca-fact-sheet. Ukuhlaziywa kweyeNkanga 19, 2020. Ifikeleleke ngoJanuwari 31, 2021.