Umbhali: Marcus Baldwin
Umhla Wokudalwa: 20 Isilimela 2021
Hlaziya Umhla: 18 Eyenkanga 2024
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I-dysplasia yomlomo wesibeleko ibhekisa kutshintsho olungaqhelekanga kwiiseli kumphezulu wesibeleko. Umlomo wesibeleko yinxalenye engezantsi yesibeleko (isibeleko) evuleka phezulu kwilungu lobufazi.

Utshintsho awungomhlaza kodwa unokukhokelela kumhlaza womlomo wesibeleko ukuba awunyangwa.

I-dysplasia yomlomo wesibeleko inokukhula nangaliphi na ixesha. Nangona kunjalo, ukulandelelwa kunye nonyango kuya kuxhomekeka kubudala bakho. I-dysplasia yomlomo wesibeleko ixhaphake kakhulu ngenxa yepillomavirus yabantu (HPV). I-HPV yintsholongwane eqhelekileyo esasazeka kunxibelelwano ngokwesondo. Zininzi iintlobo ze-HPV. Ezinye iintlobo zikhokelela kwidysplasia yomlomo wesibeleko okanye umhlaza. Ezinye iintlobo ze-HPV zinokubangela iintsumpa kumalungu esini.

Oku kulandelayo kunokunyusa umngcipheko wedysplasia yomlomo wesibeleko:

  • Ukuba neentlobano zesini ngaphambi kweminyaka eyi-18
  • Ukufumana umntwana esemncinci kakhulu
  • Ukuba namaqabane amaninzi ezesondo
  • Ukuba nezinye izifo, ezinjengesifo sephepha okanye i-HIV
  • Sebenzisa amayeza acinezela amajoni akho omzimba
  • Ukutshaya
  • Imbali yoomama yokuvezwa kwe-DES (diethylstilbestrol)

Uninzi lwexesha, akukho zimpawu.


Umboneleli wakho wezempilo uya kwenza uvavanyo lwe-pelvic ukujonga i-dysplasia yomlomo wesibeleko. Uvavanyo lokuqala luhlala luvavanyo lwePap kunye novavanyo lobukho be-HPV.

I-dysplasia yomlomo wesibeleko ebonwa kuvavanyo lwePap ibizwa ngokuba yi-squamous intraepithelial lesion (SIL). Kwingxelo yovavanyo lwePap, olu tshintsho luya kuchazwa njenge:

  • Ibanga eliphantsi (LSIL)
  • Inqanaba eliphezulu (HSIL)
  • Mhlawumbi unomhlaza (unobungozi)
  • Iiseli glandular glandular (AGC)
  • Iiseli ze-atypical squamous (ASC)

Uya kudinga iimvavanyo ezingaphezulu ukuba uvavanyo lwePap lubonisa iiseli ezingaqhelekanga okanye i-dysplasia yomlomo wesibeleko. Ukuba utshintsho belungelulanga, uvavanyo lwePap olulandelayo kunokuba yiyo yonke into efunekayo.

Umboneleli unokwenza i-biopsy ukuqinisekisa imeko. Oku kunokwenziwa ngokusetyenziswa kwecolposcopy. Nayiphi na imimandla exhalabisayo iya kufakwa kwi-biopsied. Ii-biopsies zincinci kakhulu kwaye uninzi lwabasetyhini luziva lincinci kancinci.

Idysplasia ebonwa kwi-biopsy yomlomo wesibeleko ibizwa ngokuba yi-cervical intraepithelial neoplasia (CIN). Ihlelwe ngokwamacandelo ama-3:


  • I-CIN I-dysplasia emnene
  • I-CIN II-yokumodareyitha ukuya kwi-dysplasia ephawulweyo
  • I-CIN III -i-dysplasia eqatha kwi-carcinoma in situ

Ezinye iintlobo ze-HPV ziyaziwa ukuba zibangela umhlaza womlomo wesibeleko. Uvavanyo lwe-HPV DNA lunokuchonga iintlobo ezinobungozi obuphezulu be-HPV enxulumene nalo mhlaza. Olu vavanyo lunokwenziwa:

  • Njengokuvavanywa kovavanyo lwabasetyhini abangaphezulu kweminyaka engama-30
  • Abafazi bayo nayiphi na iminyaka abaneziphumo zovavanyo lwePap ezingaqhelekanga

Unyango luxhomekeke kwinqanaba le-dysplasia. I-dysplasia emnene (i-LSIL okanye i-CIN I) inokuhamba ngaphandle konyango.

  • Unokufuna ukulandelelwa ngononophelo ngumboneleli wakho ngovavanyo oluphindaphindiweyo lwePap rhoqo kwiinyanga ezi-6 ukuya kwezi-12.
  • Ukuba utshintsho aluhambi okanye lusiba lubi, unyango luyafuneka.

Unyango lwe-dysplasia yokumodareyitha ukuya kwelukhuni okanye i-dysplasia ethambileyo engahambiyo inokubandakanya:

  • I-Cryosurgery yokuqandisa iiseli ezingaqhelekanga
  • Unyango lweLaser, olusebenzisa ukukhanya ukutshisa izicwili ezingaqhelekanga
  • I-LEEP (inkqubo ye-loop electrosurgical excision), esebenzisa umbane ukususa izicubu ezingaqhelekanga
  • Utyando lokususa izicwili ezingaqhelekanga (ikhowuni biopsy)
  • I-Hysterectomy (kwiimeko ezinqabileyo)

Ukuba une-dysplasia, kuyakufuneka ukuba uphinde uviwo rhoqo kwiinyanga ezili-12 okanye njengoko kucetyisiwe ngumboneleli wakho.


Qinisekisa ukufumana isitofu sokugonya se-HPV xa usinikwa. Olu gonyo luthintela imihlaza emininzi yomlomo wesibeleko.

Ukuchongwa kwangoko kunye nokunyanga kwangoko kunyanga iimeko ezininzi zedysplasia yomlomo wesibeleko. Nangona kunjalo, imeko inokubuyela.

Ngaphandle konyango, i-dysplasia yomlomo wesibeleko inokutshintsha ibe ngumhlaza womlomo wesibeleko.

Tsalela umnikezeli wakho ukuba uneminyaka engama-21 okanye ngaphezulu kwaye awuzange ube novavanyo lwe-pelvic kunye novavanyo lwePap.

Buza umboneleli wakho malunga nogonyo lwe-HPV. Amantombazana afumana eli chiza phambi kokuba abelane ngesondo anciphisa amathuba okuba nomhlaza womlomo wesibeleko.

Ungawunciphisa umngcipheko wokuphuhliswa kwesibeleko ngokuthatha la manyathelo alandelayo:

  • Gonyelwa i-HPV phakathi kweminyaka eli-9 ukuya kwengama-45.
  • Musa ukutshaya. Ukutshaya kwandisa umngcipheko wokuba ne-dysplasia eqatha kunye nomhlaza.
  • Musa ukulala ngesondo de ube ne-18 okanye ngaphezulu.
  • Ziqhelise ngesondo elikhuselekileyo. Sebenzisa ikhondom.
  • Ziqhelise ukuba neqabane elinye. Oku kuthetha ukuba uneqabane elinye lokwabelana ngesondo ngexesha.

Isibeleko se-intraepithelial neoplasia - idysplasia; CIN - idysplasia; Utshintsho olwenziwe kwangaphambili lomlomo wesibeleko - idysplasia; Umhlaza womlomo wesibeleko - idysplasia; Izilonda squamous intraepithelial - dysplasia; LSIL - idysplasia; HSIL - idysplasia; I-dysplasia ekumgangatho ophantsi; Idysplasia ekumgangatho ophezulu; ICarcinoma in situ - idysplasia; CIS - idysplasia; I-ASCUS - idysplasia; Iiseli glandular atypical - dysplasia; I-AGUS - idysplasia; Iiseli squamous atypical - dysplasia; Pap smear - idysplasia; I-HPV - idysplasia; Papilloma virus - dysplasia; Umlomo wesibeleko - idysplasia; IColposcopy - idysplasia

  • I-anatomy yokuzala yabasetyhini
  • Neoplasia yomlomo wesibeleko
  • Isibeleko
  • I-dysplasia yomlomo wesibeleko - uthotho

Ikholeji yaseMelika yoNyango kunye neeGynecologists. Ziqhelanise neBulletin No. 168: ukuhlolwa komhlaza womlomo wesibeleko kunye nokuthintela. IGynecol ebambekayo. Ngo-2016; 128 (4): e111-e130. IINKCUKACHA: 27661651 pubmed.ncbi.nlm.nih.gov/27661651/.

Ikholeji yaseMelika yoNyango kunye neeGynecologists. Ziqhelise iBulletin engu-140: ukulawulwa kweziphumo zovavanyo lokuvavanywa komhlaza womlomo wesibeleko kunye nezandulela zomhlaza womlomo wesibeleko. IGynecol ebambekayo. Ngo-2013; 122 (6): 1338-1367. IINKCUKACHA: 24264713 pubmed.ncbi.nlm.nih.gov/24264713/.

U-Armstrong DK. Umhlaza wamanina. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Ngomhla wama-26. IPhiladelphia, PA: Elsevier; 2020: isahl. 189.

UFreedman MS, uHunter P, uAult K, uKroger A. IKomiti yeeNgcebiso malunga neZenzo zoGonyo icebisa ishedyuli yokugonywa kwabantu abadala abaneminyaka eli-19 okanye ngaphezulu-eUnited States, 2020. MMWR Mntundini wokufa Wkly Rep. Ngo-2020; 69 (5): 133-135. IINKCUKACHA: I-32027627 pubmed.ncbi.nlm.nih.gov/32027627/.

IHacker NF. I-dysplasia yomlomo wesibeleko kunye nomhlaza. Ku: IHacker NF, iGambone JC, iHobel CJ, ii-eds. IHacker kunye neMoore's Essentials ye-Obstetrics kunye neGynecology. Umhla wesi-6. IPhiladelphia, PA: Elsevier; 2016: isahluko 38.

Iqela lomsebenzi woGonyo, iKomiti yoKhathalelo lweMpilo yaBafikisayo. Uluvo lweKomiti No. 704: ugonyo lwepapillomavirus yabantu. IGynecol ebambekayo. Ngo-2017; 129 (6): e173-e178. IINKCUKACHA: 28346275 pubmed.ncbi.nlm.nih.gov/28346275/.

URobinson CL, uBernstein H, uPoehling K, uRomero JR, uSzilagyi P. IKomiti yeeNgcebiso malunga neZenzo zoGonyo Kucetyiswa ishedyuli yokugonywa kwabantwana nakwishumi elivisayo abaneminyaka eli-18 nangaphantsi- eUnited States, 2020. MMWR Mntundini wokufa Wkly Rep. Ngo-2020; 69 (5): 130-132. IINKCUKACHA: 32027628 pubmed.ncbi.nlm.nih.gov/32027628/.

Ilungu lePalamente, iBaker ES, iSchmeler KM. I-neoplasia ye-Intraepithelial neoplasia yendlela esezantsi yesibeleko (umlomo wesibeleko, ubufazi, ubufazi): i-etiology, ukuhlolwa, ukuxilongwa, kunye nolawulo. Ku: Lobo RA, Gershenson DM, Lentz GM, Valea FA, ii-eds. Gynecology egqibeleleyo. Umhla wesi-7. IPhiladelphia, PA: Elsevier; Ngo-2017: isahluko 28.

ISaslow D, uSolomon D, uLawson HW, et al; IKomiti yeZikhokelo ze-ACS-ASCCP-ASCP yoMhlaza weSibeleko. Umbutho waseMelika woMhlaza, uMbutho waseMelika weColposcopy kunye neCathology Pathology, kunye noMbutho waseMelika kwizikhokelo zovavanyo lwezonyango kuthintelo kunye nokufunyanwa komhlaza womlomo wesibeleko kwangoko. Umhlaza kwi-CA. Ngo-2012; 62 (3): 147-172. IINKCUKACHA: 22422631 pubmed.ncbi.nlm.nih.gov/22422631/.

Umsebenzi woKhuseleko kwi-US, Curry SJ, Krist AH, Owens DK, et al. Ukuvavanywa komhlaza womlomo wesibeleko: Ingxelo yengcebiso yamandla okhuseleko e-US. JAMA. 2018; 320 (7): 674-686. IINKCUKACHA: 30140884 pubmed.ncbi.nlm.nih.gov/30140884/.

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