Isifo seReye

I-Reye syndrome ngequbuliso (etsolo) yomonakalo wobuchopho kunye neengxaki zomsebenzi wesibindi. Le meko ayinaso isizathu esaziwayo.

Esi sifo senzeke kubantwana abanikwe i-aspirin xa benenkukhu yenkukhu okanye umkhuhlane. Isifo seReye sinqabile kakhulu. Kungenxa yokuba i-aspirin ayisacetyiswa ukuba isetyenziswe rhoqo ebantwaneni.

Akukho sizathu saziwayo seReye syndrome. Ngokuqhelekileyo kubonakala kubantwana abaneminyaka engama-4 ukuya kwe-12. Uninzi lweziganeko ezenzeka kunye ne-chickenpox kubantwana abaneminyaka engama-5 ukuya kwe-9. Iimeko ezenzeka ngomkhuhlane zihlala zihlala kubantwana abaneminyaka eyi-10 ukuya kwe-14.

Abantwana abane-Reye syndrome bagula ngequbuliso. Isifo esihlala siqala ngokugabha. Inokuhlala iiyure ezininzi. Ukugabha kulandelwa ngokukhawuleza kukungakhathali kunye nokuziphatha okukhohlakeleyo. Njengokuba imeko isiba mandundu, umntwana usenokungakwazi ukuhlala ephaphile kwaye ethe qwa.

Ezinye iimpawu zeReye syndrome:

• Ukudideka
• Ukuhamba
• Ukuphulukana nokuqonda okanye isiqaqa
• Utshintsho lwengqondo
• Isicaphucaphu nokugabha
• Ukuxhuzula
• Ukubekwa ngokungaqhelekanga kweengalo kunye nemilenze (ukunyanzeliswa kwesimo). Iingalo zandiswa ngokuthe tye zajongiswa emzimbeni, imilenze ibanjwe nkqo, kwaye iinzwane zikhonjwe ezantsi

Ezinye iimpawu ezinokubakho kwesi sifo zibandakanya:

• Umbono kabini
• Ukuphulukana nokuva
• Ukuphulukana nomsebenzi wemisipha okanye ukukhubazeka kweengalo okanye imilenze
• Ubunzima bokuthetha
• Ubuthathaka kwiingalo okanye emilenzeni

Ezi mvavanyo zilandelayo zinokusetyenziselwa ukufumanisa isifo seReye:

• Uvavanyo lwekhemesti yegazi
• Intloko ye-CT okanye intloko ye-MRI scan
• Isibindi se-biopsy
• Uvavanyo lomsebenzi wesibindi
• Uvavanyo lwe-serum ammonia
• Impompo yomqolo

Akukho lonyango luthile kule meko. Umboneleli wezempilo uya kubeka esweni uxinzelelo kwingqondo, iigesi zegazi, kunye ne-acid acid-base balance (pH).

Unyango lunokubandakanya:

• Inkxaso yokuphefumla (umatshini wokuphefumla unokufuneka ngexesha lokudakumba)
• IiFluids nge-IV ukubonelela nge-electrolyte kunye neglucose
• Ii-Steroids ukunciphisa ukudumba engqondweni

Ukusebenza kakuhle komntu kuxhomekeke kubukrakra bayo nayiphi na ikhoma, kunye nezinye izinto.

Iziphumo zabo basindayo kwisiqendu esibukhali kunokuba kuhle.

Iingxaki zinokubandakanya:

• Coma
• Ukonakala okungapheliyo kwengqondo
• Ukuxhuzula

Xa kunganyangwa, ukuxhuzula kunye nokufa kungasongela ubomi.

Yiya kwigumbi likaxakeka okanye fowunela inombolo yongxamiseko yendawo (enje nge-911) ngokukhawuleza ukuba umntwana wakho:

• Ukudideka
• Ukuhamba
• Olunye utshintsho lwengqondo

Ungaze unike i-aspirin yomntwana ngaphandle kokuba uxelelwe njalo ngumboneleli wakho.

Xa umntwana kufuneka athathe i-aspirin, unakekele ukunciphisa umngcipheko womntwana wokufumana isifo sentsholongwane, njengomkhuhlane kunye nenkukhu. Kunqande iasprini iiveki ezimbalwa emva kokuba umntwana efumene iyeza lokugonya i-varicella (chickenpox).

Qaphela: Amanye amayeza angaphandle kwekhawuntara, anjengePepto-Bismol kunye nezinto ezineoyile yesikhephe sasebusika nazo ziqulathe iiasprini ezibizwa ngokuba zii-salicylates. SUKUZINIKELA oku kumntwana onomkhuhlane okanye onefiva.

• Inkqubo yokugaya ukutya

UAronons JK. Acetylsalicylic acid. Ku: Aronson JK, ed. Iziphumo ebezingalindelekanga zikaMeyler zeziyobisi. Ngomhla we-16. I-Waltham, MA: Elsevier BV ;; Ngo-2016: 26-52.

UCherry JD. Isifo seReye. Ku: UCherry JD, uHarrison GJ, uKaplan SL, uSteinbach WJ, uHotez PJ, ii-eds. Incwadi kaFeigin kunye neCherry yezifo ezosulelayo zabantwana. Ngomhla we-8. IPhiladelphia, PA: Elsevier; I-2019: isahluko 50.

UJohnston MV. I-Encephalopathies. Ku: Kliegman RM, St Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, ii-eds. Incwadi kaNelson yeNcwadi yePediatrics. Umhla wama-21. IPhiladelphia, PA: Elsevier; 2020: isahluko 616.