Cwangcisa icandelo 4

Ukuzalisa icandelo 4 luvavanyo lwegazi olulinganisa umsebenzi weprotein ethile. Le protein yinxalenye yenkqubo yokuncedisa. Inkqubo yokuncedisana liqela leeprotein eziphantse zibe ngama-60 ezifumaneka kwiplasma okanye kumphezulu weeseli ezithile.

Iiproteni zisebenza kunye namajoni akho omzimba kwaye zidlala indima ekukhuseleni kusulelo. Ziyanceda nokususa iiseli ezifileyo kunye nezinto zangaphandle emzimbeni. Rhoqo, abantu banokufumana ilifa lokusilela kwezinye iiprotein ezincedisayo. Aba bantu bathambekele kusulelo oluthile okanye ukuphazamiseka komzimba.

Zilithoba iiprotheyini zokuncedisa. Babhalwe i-C1 nge-C9. Eli nqaku lichaza uvavanyo olulinganisa i-C4.

Igazi litsalwa emthanjeni. Umthambo ovela ngaphakathi kwengqiniba okanye umva wesandla udla ngokusetyenziswa.

Inkqubo imi ngolu hlobo lulandelayo:

• Indawo icocwa nge-antiseptic.
• Umboneleli wezempilo usonga ibhanti yelastic ejikeleze ingalo ephezulu ukufaka uxinzelelo kuloo ndawo kwaye enze umthambo udumbe ligazi.
• Umboneleli ufaka inaliti ngobunono emthanjeni.
• Igazi liqokelela kwi-vial engena moya okanye ityhubhu eqhotyoshelwe kule naliti. Ibhanti e-elastic isuswe engalweni yakho.
• Nje ukuba igazi liqokelelwe, inaliti iyasuswa. Indawo yokubhoboza igqunyiwe ukunqanda ukopha.

Kwiintsana okanye kubantwana abancinci, isixhobo esibukhali esibizwa ngokuba yi-lancet sinokusetyenziselwa ukugqobhoza ulusu kunye nokwenza igazi. Igazi liqokelelwa kwityhubhu yeglasi encinci ebizwa ngokuba yipipette, okanye kwisilayidi okanye kumtya wovavanyo. Ibhandeji inokufakwa ngaphezulu kwendawo ukuba kukho ukopha.

Akukho lungiselelo lukhethekileyo luyafuneka.

Xa kufakwa inaliti ukutsala igazi, abanye abantu baziva iintlungu eziphakathi. Abanye banokuziva ngathi batyhafile okanye batyhafile. Emva koko, kunokubakho ukuthotywa okuthile.

I-C3 kunye ne-C4 zezona zinto zixhaswa ngokulinganayo. Xa inkqubo yokuncedisa ivuliwe ngexesha lokudumba, amanqanaba okuxhasa iiproteni anokuhla. Umsebenzi wokuncedisa unokulinganiswa ukufumanisa ukuba sisifo esibi kangakanani na okanye ukuba unyango lusebenza.

Uvavanyo lokuncedisa lungasetyenziselwa ukubeka esweni abantu abanesifo sokuzimela. Umzekelo, abantu abanesistim esebenzayo ye-lupus erythematosus banokuba namanqanaba asezantsi kunalawo aqhelekileyo okuxhasa iiprotein C3 kunye neC4.

Umsebenzi wokuncedisa uyahluka emzimbeni wonke. Kubantu abane-rheumatoid arthritis, umsebenzi wokuncedisa unokuba yinto eqhelekileyo okanye ephezulu-kunesiqhelo egazini, kodwa isezantsi kakhulu kunesiqhelo kulwelo oluhlangeneyo.

Amanqanaba aqhelekileyo e-C4 zii-15 ukuya kwi-45 zeemiligram kwidesilitha nganye (mg / dL) (0.15 ukuya 0.45 g / L).

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Thetha nomboneleli wakho malunga nentsingiselo yeziphumo zakho zovavanyo.

Imizekelo engentla ibonisa imilinganiselo eqhelekileyo yeziphumo zolu vavanyo. Ezinye iilabhoratri zisebenzisa imilinganiselo eyahlukeneyo okanye zinokuvavanya iisampulu ezahlukeneyo.

Ukonyusa imisebenzi yokuxhasa kunokubonwa ku:

• Umhlaza
• Ukudumba okwenziwa sisilonda sikabhobhosi

Ukuncipha komsebenzi wokuncedisa kunokubonwa ku:

• Usulelo lwebacteria (ngakumbi iNeisseria)
• Isibindi
• IGlomerulonephritis
• Hepatitis
• I-angioedema yelifa
• Ukhatywa kwezintso
• Lupus nephritis
• Ukungondleki
• Inkqubo ye lupus erythematosus
• Ukunqongophala kunqabile okuza kuzuzwa njengelifa

Iingozi ezinxulunyaniswa nokutsalwa kwegazi zincinci, kodwa zinokubandakanya:

• Ukopha kakhulu
• Ukufa isiqaqa okanye ukuziva ungenantloko
• I-Hematoma (igazi eliqokelela phantsi kwesikhumba)
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

C4

• Uvavanyo lwegazi

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IMerle NS, uNowa R, iHalbwachs-Mecarelli L, iFremeaux-Bacchi V, iRoumenina LT. Inkqubo yokugcwalisa icandelo II: indima ekukhuseleni. I-Immunol yangaphambili. Ngo-2015; 6: 257. IINKCUKACHA: 26074922 www.ncbi.nlm.nih.gov/pubmed/26074922.

USullivan KE, iGrumach AS. Inkqubo yokuncedisa. Ku: Adkinson NF, Bochner BS, Burks AW, et al, ii-eds. I-Middleton's Allergy: Imigaqo kunye nokuziqhelanisa. Ngomhla we-8. IPhiladelphia, PA: Elsevier Saunders; 2014: isahl 8.