Uvavanyo lwegazi lwe-Aspartate aminotransferase (AST)

Uvavanyo lwegazi lwe-aspartate aminotransferase (AST) kwinqanaba le-enzyme AST egazini.

Isampulu yegazi iyafuneka.

Akukho lungiselelo lukhethekileyo luyafuneka.

Xa kufakwa inaliti ukutsala igazi, abanye abantu baziva iintlungu eziphakathi. Abanye baziva behlaba okanye behlaba kuphela. Emva koko, kunokubakho ukubetha okanye ukukrala kancinci. Oku kuya kuhamba kungekudala.

I-AST yi-enzyme efumaneka kumanqanaba aphezulu kwisibindi, intliziyo kunye nezihlunu. Kufunyenwe nakwimali encinci kwezinye izicubu. I-enzyme yiprotein ebangela utshintsho oluthile lweekhemikhali emzimbeni.

Ukwenzakala kwesibindi kuphumela ekukhululweni kwe-AST egazini.

Olu vavanyo lwenziwa ikakhulu kunye nolunye uvavanyo (njenge-ALT, ALP, kunye ne-bilirubin) ukufumanisa nokujonga isifo sesibindi.

Uluhlu oluqhelekileyo ngu-8 ukuya ku-33 U / L.

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye zinokuvavanya iisampulu ezahlukeneyo. Thetha nomboneleli wakho wezempilo malunga nentsingiselo yeziphumo zakho zovavanyo.

Ukunyuka kwenqanaba le-AST kuhlala kungumqondiso wesifo sesibindi. Isifo sesibindi sinokwenzeka ngakumbi xa amanqanaba ezinto ahlolwe lolunye uvavanyo lwegazi lesibindi nawo enyukile.

Inqanaba le-AST elonyukayo linokubangelwa yiyo nayiphi na kwezi zinto zilandelayo:

• Ukuqhekeka kwesibindi (i-cirrhosis)
• Ukufa kwezihlunu zesibindi
• Ukuhlaselwa yintliziyo
• Intsimbi eninzi emzimbeni (hemochromatosis)
• Ukudumba kunye nokutsha kwesibindi (hepatitis)
• Ukungabikho kokuhamba kwegazi kwisibindi (isibindi ischemia)
• Umhlaza wesibindi okanye ithumba
• Ukusetyenziswa kweziyobisi eziyityhefu kwisibindi, ngakumbi ukusetyenziswa kotywala
• Mononucleosis ("mono")
• Isifo semisipha okanye umothuko
• I-pancreas edumbileyo kunye ne-inflamed (pancreatitis)

Inqanaba le-AST linokunyuka kwakhona emva:

• Ukutshisa (nzulu)
• Iinkqubo zentliziyo
• Ukuhlutha
• Ugqirha

Ukukhulelwa kunye nokuzilolonga kunokubangela ukonyuka kwenqanaba le-AST.

Akukho mngcipheko ubandakanyekileyo ekuthatheni igazi lakho. Imithambo yahluka ngobukhulu ukusuka komnye umntu ukuya komnye nokusukela kwelinye icala lomzimba ukuya kwelinye. Ukuthatha igazi kwabanye abantu kunokuba nzima ngakumbi kunabanye.

Iingozi ezinxulunyaniswa nokutsalwa kwegazi zincinci, kodwa zinokubandakanya:

• Ukufa isiqaqa okanye ukuziva ungenantloko
• Ukopha kakhulu
• Ukugqobhoza okuninzi ukufumana imithambo
• I-Hematoma (ukuqokelela kwegazi phantsi kolusu)
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

I-aspartate aminotransferase; I-serum glutamic-oxaloacetic transaminase; I-SGOT

IChernecky CC, iBerger BJ. I-aspartate aminotransferase (AST, aspartate transaminase, SGOT) -iserum. Ku: IChernecky CC, iBerger BJ, ii-eds. Iimvavanyo zaselebhu kunye neenkqubo zokuqonda isifo. Umhla wesi-6. ISt Louis, MO: Elsevier Saunders; Ngo-2013: 172-173.

UPincus MR, u-Tierno PM, uGleeson E, uBowne WB, uBluth MH. Ukuvavanywa kokusebenza kwesibindi. Ku: McPherson RA, Pincus MR, ii-eds. Ukuchongwa kweKlinikhi kaHenry kunye noLawulo ngeendlela zeLebhu. Umhla we-23. ISt Louis, MO: Elsevier; I-2017: isahluko 21.

IPratt DS. I-chemistry yesibindi kunye novavanyo lomsebenzi. Ku: UFeldman M, uFriedman LS, uBrandt LJ, ii-eds. Sleisenger kunye neFordtran's Gastrointestinal and Liver Disease. Ngomhla we-10. IPhiladelphia, PA: Elsevier Saunders; Ngo-2016: isahluko 73.