Uvavanyo lobungakanani be-nephelometry

Ubungakanani be-nephelometry luvavanyo lwelebhu ukukhawulezisa ngokuchanekileyo nangokuchanekileyo amanqanaba eeproteni ezithile ezibizwa ngokuba zii-immunoglobulins egazini. Ii-Immunoglobulins izilwa-buhlungu ezinceda ukulwa usulelo.

Olu vavanyo ngokuthe ngqo luthatha i-immunoglobulins IgM, IgG, kunye ne-IgA.

Isampulu yegazi iyafuneka.

Unokucelwa ukuba ungatyi okanye usele nantoni na iiyure ezi-4 phambi kovavanyo.

Xa kufakwa inaliti ukutsala igazi, abanye abantu baziva iintlungu eziphakathi. Abanye baziva behlaba okanye behlaba kuphela. Emva koko, kunokubakho ukubetha okanye ukutyumza kancinci. Oku kuya kuhamba kungekudala.

Uvavanyo lubonelela ngemilinganiselo ekhawulezileyo nechanekileyo yexabiso lee-immunoglobulins IgM, IgG, kunye ne-IgA.

Iziphumo eziqhelekileyo zezi immunoglobulin zintathu zezi:

• IgG: 650-1600 milligrams ngedesilitha nganye (mg / dL), okanye 6.5 kuye kwi-16.0 yeegramu kwilitha nganye (g / L)
• IgM: 54 ukuya ku-300 mg / dL, okanye ngo-540 ukuya ku-3000 mg / L
• IgA: 40 ukuya ku-350 mg / dL, okanye kuma-400 ukuya kuma-3500 mg / L

Imizekelo engentla ibonisa imilinganiselo eqhelekileyo kwezi ziphumo zovavanyo. Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Thetha nogqirha wakho malunga nentsingiselo yeziphumo zakho zovavanyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye ukuvavanya iisampulu ezahlukeneyo.

Inqanaba elonyukayo le-IgG linokubangelwa:

• Usulelo olungapheliyo okanye ukudumba
• Hyperimmunization (ngaphezulu kwenani eliqhelekileyo lamajoni omzimba athile)
• IgG multiple myeloma (uhlobo lomhlaza wegazi)
• Isifo sesibindi
• Irheumatoid Arthritis

Ukuhla kwamanqanaba e-IgG kunokuba ngenxa:

• I-Agammaglobulinemia (amanqanaba asezantsi kakhulu ee-immunoglobulins, isifo esinqabileyo)
• Ileukemia (umhlaza wegazi)
• I-myeloma eninzi (umhlaza womongo wethambo)
• I-Preeclampsia (uxinzelelo lwegazi oluphezulu ngexesha lokukhulelwa)
• Unyango ngamayeza athile e-chemotherapy

Ukunyuswa kwamanqanaba e-IgM kunokuba ngenxa:

• Mononucleosis
• I-Lymphoma (umhlaza wesisu se-lymph)
• IWaldenström macroglobulinemia (umhlaza weeseli ezimhlophe zegazi)
• I-myeloma eninzi
• Irheumatoid Arthritis
• Usulelo

Ukuhla kwamanqanaba e-IgM kunokubangelwa:

• I-Agammaglobulinemia (inqabile kakhulu)
• Ileukemia
• I-myeloma eninzi

Ukunyuka kwamanqanaba e-IgA kunokuba ngenxa:

• Izifo ezingapheliyo, ngakumbi iphecana lesisu
• Isifo sesisu sokuvuvukala, njengesifo sikaCrohn
• I-myeloma eninzi

Ukuhla kwamanqanaba e-IgA kunokuba ngenxa:

• I-Agammaglobulinemia (inqabile kakhulu)
• Ukuswela ilifa le-IgA
• I-myeloma eninzi
• Isifo sesisu esikhokelela ekuphulukaneni neprotein

Olunye uvavanyo luyafuneka ukuqinisekisa okanye ukuxilonga naziphi na iimeko ezingentla.

Akukho mngcipheko ubandakanyekileyo ekuthatheni igazi lakho. Imithambo kunye nemithambo iyahluka ngobukhulu ukusuka komnye umntu ukuya komnye nakwelinye icala lomzimba liye kwelinye. Ukuthatha igazi kwabanye abantu kunokuba nzima ngakumbi kunabanye.

Eminye imingcipheko enxulumene nokutsalwa kwegazi incinci, kodwa inokubandakanya:

• Ukopha kakhulu
• Ukufa isiqaqa okanye ukuziva ungenantloko
• Ukugqobhoza okuninzi ukufumana imithambo
• I-Hematoma (igazi eliqokelela phantsi kwesikhumba)
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

Ubungakanani beemunoglobulin

• Uvavanyo lwegazi

UAbraham RS. Uvavanyo lwempendulo zomzimba ezisebenzayo kwi-lymphocyte. Ku: Rich RR, Fleisher TA, Shearer WT, Schroeder HW, Ambalwa AJ, Weyand CM, ii-eds. I-Clinical Immunology: Imigaqo kunye nokuziqhelanisa. Umhla we-5. IPhiladelphia, PA: Elsevier; I-2019: isahluko 93.

IMcPherson RA. Iiproteni ezithile. Ku: McPherson RA, Pincus MR, ii-eds. Ukuchongwa kweKlinikhi kaHenry kunye noLawulo ngeendlela zeLebhu. Umhla we-23. ISt Louis, MO: Elsevier; Ngo-2017: isahluko 19.