Irheumatoid factor (RF)

Rheumatoid factor (RF) luvavanyo lwegazi olulinganisa isixa somzimba omzimba weRF egazini.

Uninzi lwexesha, igazi litsalwa kumthambo ngaphakathi kwengqiniba okanye ngasemva kwesandla.

Kwiintsana okanye abantwana abancinci, isixhobo esibukhali esibizwa ngokuba yi-lancet sinokusetyenziselwa ukugqobhoza ulusu.

• Igazi liqokelela kwityhubhu yeglasi encinci ebizwa ngokuba yipipette, okanye kwisilayidi okanye kumtya wovavanyo.
• Ibhandeji ibekwa phezu kwendawo ukunqanda ukopha.

Uninzi lwexesha, awudingi ukuthatha manyathelo akhethekileyo ngaphambi kolu vavanyo.

Unokuziva iintlungu okanye ulwamvila xa kufakwa inaliti. Unokuziva ubethwa sisiza emva kokuba kuthathwe igazi.

Olu vavanyo luhlala lusetyenziswa ukunceda ukufumanisa isifo samathambo okanye isifo se-Sjögren.

Iziphumo zihlala zixelwa ngenye yeendlela ezimbini:

• Ixabiso, eliqhelekileyo lingaphantsi kwe-15 IU / mL
• Ithagethi, eqhelekileyo ngaphantsi kwe-1: 80 (1 ukuya kuma-80)

Ukuba iziphumo zingaphezulu kwenqanaba eliqhelekileyo, kulungile. Inani eliphantsi (iziphumo ezibi) zihlala zithetha ukuba awunaso isifo samathambo okanye isifo se-Sjögren. Nangona kunjalo, abanye abantu abanezi meko banesimo esibi okanye esisezantsi seRF.

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Thetha nomboneleli wakho wezempilo malunga nentsingiselo yeziphumo zakho zovavanyo.

Iziphumo ezingaqhelekanga zithetha ukuba uvavanyo luthi unayo, okuthetha ukuba inqanaba eliphezulu le-RF lifunyenwe egazini lakho.

• Uninzi lwabantu abane-rheumatoid arthritis okanye i-Sjögren syndrome baneemvavanyo ze-RF ezilungileyo.
• Ephakamileyo inqanaba, kokukhona kunokwenzeka ukuba enye yezi meko ikhoyo. Kukho nolunye uvavanyo kwezi ngxaki ezinceda ukuba kufunyaniswe isifo.
• Ayinguye wonke umntu onenqanaba eliphezulu le-RF onesifo samathambo okanye isifo seSjögren.

Umboneleli wakho kufuneka enze olunye uvavanyo lwegazi (anti-CCP antibody), ukunceda ukufumanisa isifo samathambo (RA). I-anti-CCP antibody ichaze ngakumbi i-RA kune-RF. Uvavanyo oluqinisekileyo lwe-antibody yeCCP kuthetha ukuba i-RA mhlawumbi sisifo esichanekileyo.

Abantu abanezifo zilandelayo banokuba namanqanaba aphezulu e-RF:

• IHepatitis C
• Inkqubo ye lupus erythematosus
• Dermatomyositis kunye ne-polymyositis
• I-Sarcoidosis
• I-cryoglobulinemia exutyiweyo
• Isifo esixubileyo sesifo

Amanqanaba aphezulu kunesiqhelo e-RF anokubonwa kubantu abanezinye iingxaki zonyango. Nangona kunjalo, la manqanaba aphezulu e-RF awanakusetyenziselwa ukufumanisa ezinye iimeko:

• UGawulayo, i-hepatitis, umkhuhlane, i-mononucleosis esosulelayo kunye nezinye izifo ezosulelayo
• Izifo ezithile zezintso
• I-Endocarditis, isifo sephepha kunye nezinye izifo ezibangelwa ziintsholongwane
• Usulelo lwe-parasite
• Ileukemia, myeloma emininzi, kunye neminye imihlaza
• Isifo esingapheliyo semiphunga
• Isifo sesibindi esinganyangekiyo

Ngamanye amaxesha, abantu abasempilweni kwaye abanayo enye ingxaki yezonyango baya kuba nenqanaba eliphezulu le-RF eliqhelekileyo.

• Uvavanyo lwegazi

UAletaha D, uNeogi T, uSilman AJ, et al. Iikhrayitheriya zokuhlelwa kwamathambo e-Rheumatoid ye-2010: Ikholeji yaseMelika yeRheumatology / iEuropean League ngokuchasene neRheumatism yokusebenzisana. U-Ann Rheum Dis. Ngo-2010; 69 (9): 1580-1588. IINKCUKACHA: 20699241 www.ncbi.nlm.nih.gov/pubmed/20699241.

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IHoffmann MH, iTrouw LA, uSteiner G.Izixhobo ezizenzekelayo kwi-rheumatoid arthritis. Ku: Hochberg MC, Gravallese EM, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH, ii-eds. Rheumatology. Umhla wesi-7. IPhiladelphia, PA: Elsevier; I-2019: isahluko 99.

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IPisetsky DS. Uvavanyo lweLabhoratri kwizifo ze-rheumatic. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Umhla wama-25. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 257.

von Mühlen CA, Fritzler MJ, Chan EKL. Uvavanyo lweklinikhi kunye nolabhoratri lwezifo zamathambo. Ku: McPherson RA, Pincus MR, ii-eds. Ukuchongwa kweKlinikhi kaHenry kunye noLawulo ngeendlela zeLebhu. Umhla we-23. ISt Louis, MO: Elsevier; Ngo-2017: isahluko 52.