Uvavanyo lwe-antigen lokuhambelana ngokufanelekileyo

Uvavanyo lwegazi lwe-antiocompatibility lwe-antigen lujonga iiproteni ezibizwa ngokuba zii-antigen leukocyte antigen (HLAs). Ezi zifumaneka kumphezulu phantse wazo zonke iiseli emzimbeni womntu. Ii-HLAs zifunyanwa ngesixa esikhulu kumphezulu weeseli ezimhlophe zegazi. Banceda amajoni omzimba axelele umahluko phakathi kwezicubu zomzimba kunye nezinto ezingezizo ezomzimba wakho.

Igazi litsalwa emthanjeni. Unokuziva iintlungu okanye ulwamvila xa kufakwa inaliti. Emva koko, kunokubakho ukuthotywa okuthile.

Awudingi ukulungiselela olu vavanyo.

Iziphumo ezivela kolu vavanyo zinokusetyenziselwa ukufumanisa ukulingana okufanelekileyo kwezicwili kunye nokufakelwa komzimba. Oku kunokubandakanya ukufakelwa kwezintso okanye ukufakelwa komongo wethambo.

Inokusetyenziselwa:

• Ukuchonga ukuphazamiseka okuthile okuzenzekelayo. Ukusetyenziswa gwenxa kweziyobisi ngumzekelo.
• Chonga ubudlelwane phakathi kwabantwana nabazali xa olo lwalamano lubuzwa.
• Ukubeka iliso kunyango ngamanye amayeza.

Uneseti encinci yee-HLAs ezidlulisiweyo zivela kubazali bakho. Abantwana, ngokwe-avareji, baya kuba nesiqingatha se-HLAs yabo ehambelana nesiqingatha soomama kunye nesiqingatha se-HLAs yabo esilingana nesiqingatha sikayise.

Akunakulindeleka ukuba abantu ababini abangadibaniyo babe ne-HLA efanayo. Nangona kunjalo, amawele afanayo anokufana.

Ezinye iintlobo ze-HLA zixhaphake kakhulu kwizifo ezithile ezizimele. Umzekelo, i-antigen ye-HLA-B27 ifunyanwa kubantu abaninzi (kodwa ayingabo bonke) abane-ankylosing spondylitis kunye neReiter syndrome.

Akukho mngcipheko ubandakanyekileyo ekuthatheni igazi lakho. Imithambo kunye nemithambo iyahluka ngobukhulu ukusuka komnye umntu ukuya komnye nakwelinye icala lomzimba liye kwelinye. Ukuthatha igazi kwabanye abantu kunokuba nzima ngakumbi kunabanye.

Eminye imingcipheko enxulumene nokutsalwa kwegazi incinci, kodwa inokubandakanya:

• Ukufa isiqaqa okanye ukuziva ungenantloko
• Ukugqobhoza okuninzi ukufumana imithambo
• I-Hematoma (igazi elakhiweyo phantsi kolusu)
• Ukopha kakhulu
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

Ukuchwetheza kwe-HLA; Ukuchwetheza kwethishu

• Uvavanyo lwegazi
• Izicubu zamathambo

Fagoaga OKANYE. I-antigen ye-leukocyte yabantu: eyona nto inzima kakhulu kukungalingani komntu. Ku: McPherson RA, Pincus MR, ii-eds. Ukuchongwa kweKlinikhi kaHenry kunye noLawulo ngeendlela zeLebhu. Umhla we-23. ISt Louis, MO: Elsevier; Ngo-2017: isahluko 49.

IMonos DS, iWinchester RJ. Ubunzima obukhulu bokuhambelana kwayo. Ku: Rich RR, Fleisher TA, Shearer WT, Schroeder HW, Ambalwa AJ, Weyand CM, ii-eds. I-Clinical Immunology: Imigaqo kunye nokuziqhelanisa. Umhla we-5. IPhiladelphia, PA: Elsevier; I-2019: isahluko 5.

U-Wang E, uAdams S, uStroncek DF, uMarincola FM. I-antigen leukocyte yabantu kunye neenkqubo ze-antigen ze-neutrophil yabantu. Ku: Hoffman R, Benz EJ, Silberstein LE, et al, ii-eds. I-Hematology: Imigaqo esisiseko kunye nokuziqhelanisa. Umhla wesi-7. IPhiladelphia, PA: Elsevier; I-2018: isahluko 113.