Uvavanyo lwe-protein ye-electrophoresis yomchamo

Uvavanyo lwe-urine protein electrophoresis (UPEP) lusetyenziselwa ukuqikelela ukuba zingakanani na iiprotein ezithile ezisemchameni.

Isampulu yomchamo ococekileyo iyafuneka. Indlela yokubambisa ecocekileyo isetyenziselwa ukunqanda iintsholongwane ezivela kwilungu lobudoda okanye kwilungu lobufazi ekungeneni kwisampulu yomchamo. Ukuqokelela umchamo wakho, umboneleli wezempilo unokukunika ikiti yokubambisa ecocekileyo ekhethekileyo enesisombululo sokucoca kunye nokusula okungenazintsholongwane. Landela imiyalelo ngokuchanekileyo.

Emva kokuba unikeze isampuli yomchamo, uthunyelwa elebhu. Apho, ingcali yelabhoratri iya kubeka isampuli yomchamo kwiphepha elikhethekileyo kwaye ifake umbane wombane. Iiproteni zihamba kwaye zenze amaqela abonakalayo. Oku kutyhila izixa ngokubanzi zeprotheyini nganye.

Umboneleli wakho angakuxelela ukuba uyeke ukuthatha amayeza athile anokuphazamisa uvavanyo. Amayeza anokuchaphazela iziphumo zovavanyo aquka:

• Chlorpromazine
• ICorticosteroids
• Isoniazid
• Neomycin
• Phenacemide
• IiSalicylates
• Isulfonamides
• ITolbutamide

Sukuyeka ukuthatha nawaphi na amayeza ngaphandle kokuqala uthethe nomboneleli wakho.

Olu vavanyo lubandakanya kuphela ukuchama okuqhelekileyo. Akukho buhlungu.

Ngokwesiqhelo akukho protein, okanye kuphela sisixa esincinci seprotheni kumchamo. Inani eliphezulu ngokungaqhelekanga leprotini kumchamo inokuba luphawu lweengxaki ezahlukeneyo.

I-UPEP inokucetyiswa ukunceda ukumisela unobangela weprothini kumchamo. Okanye kunokwenziwa kuvavanyo lokuvavanya ukulinganisa izixa ezahlukeneyo zeentlobo ezahlukeneyo zeeproteni kumchamo. I-UPEP ifumana iintlobo ezimbini zeprotheyini: ialbumin kunye neeglobulin.

Akukho sixa sibalulekileyo seiglobulin ezifumaneka kumchamo. I-albhamu ye-urine ingaphantsi kwe-5 mg / dL.

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye ukuvavanya iisampulu ezahlukeneyo. Thetha nogqirha wakho malunga nentsingiselo yeziphumo zakho zovavanyo.

Ukuba isampuli yomchamo inexabiso elibonakalayo le-globulin okanye ngaphezulu kwenqanaba eliqhelekileyo le-albhamuin, oko kunokuthetha nakuphi na oku kulandelayo:

• Ukudumba okukhulu
• Iprotheni engaqhelekanga ekwakhiweni kwethishu nakwizitho (amyloidosis)
• Ukuncipha komsebenzi wezintso
• Isifo sezintso ngenxa yeswekile (isifo seswekile)
• Ukungaphumeleli kwezintso
• Uhlobo lomhlaza wegazi obizwa ngokuba yi-myeloma emininzi
• Iqela leempawu ezibandakanya iprotein kumchamo, inqanaba leeprotein ezisezantsi egazini, ukudumba (nephrotic syndrome)
• Usulelo olunamandla lomchamo

Akukho bungozi kolu vavanyo.

Umchamo protein protrophoresis; PHAKAMA; Uninzi lwe-myeloma-UPEP; Waldenström macroglobulinemia - UPEP; Amyloidosis - UPEP

• Inkqubo yomchamo wamadoda

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IMcPherson RA. Iiproteni ezithile. Ku: McPherson RA, Pincus MR, ii-eds. Ukuchongwa kweKlinikhi kaHenry kunye noLawulo ngeendlela zeLebhu. Umhla we-23. ISt Louis, MO: Elsevier; Ngo-2017: isahluko 19.

URajkumar SV, iDispenzieri A. Multiple myeloma kunye nokuphazamiseka okunxulumene noko. Ku: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, ii-eds. I-Oncology yeklinikhi yase-Abeloff. Umhla wesi-6. IPhiladelphia, PA: Elsevier; 2020: isahl. 101.