Immunoelectrophoresis - umchamo

I-urine immunoelectrophoresis luvavanyo lweelebhu olulinganisa ii-immunoglobulins kwisampulu yomchamo.

Ii-Immunoglobulins ziiproteni ezisebenza njengezikhuseli zomzimba, ezilwa nosulelo. Kukho iintlobo ezahlukeneyo zezi proteni zilwa iintlobo ezahlukeneyo zosulelo. Ezinye ii-immunoglobulins zinokungaqhelekanga kwaye zinokubangelwa ngumhlaza.

Amajoni omzimba anokulinganiswa nasegazini.

Isampulu yomchamo ococekileyo iyafuneka.Indlela yokubambisa ecocekileyo isetyenziselwa ukunqanda iintsholongwane ezivela kwilungu lobudoda okanye kwilungu lobufazi ekungeneni kwisampulu yomchamo. Ukuqokelela umchamo wakho, umboneleli wezempilo unokukunika ikiti yokubambisa ecocekileyo ekhethekileyo enesisombululo sokucoca kunye nokusula okungenazintsholongwane. Landela imiyalelo ngokuchanekileyo.

Emva kokuba unikeze isampuli yomchamo, uthunyelwa elebhu. Apho, ingcali yelabhoratri iya kubeka isampuli yomchamo kwiphepha elikhethekileyo kwaye ifake umbane wombane. Iiproteni ezahlukeneyo ziyahamba kwaye zenze amabhanti abonakalayo, atyhila izixa ngokubanzi zeprotheyini nganye.

Umboneleli wakho unokukucela ukuba uqokelele umchamo wokuqala wasekuseni, oyena ujolise kakhulu.

Ukuba uthatha ingqokelela kusana, unokufuna iibhegi zokuqokelela ezongezelelweyo.

Uvavanyo lubandakanya kuphela ukuchama okuqhelekileyo, kwaye akukho kungonwabi.

Olu vavanyo lusetyenziselwa ukulinganisa izixa zeemunoglobulins ezahlukeneyo kumchamo. Rhoqo, yenziwa emva kokufunyanwa komchamo isixa esikhulu seprotein.

Ngokwesiqhelo akukho protein, okanye kuphela sisixa esincinci seprotheni kumchamo. Xa kukho iprotein emchameni, ihlala inealbumin.

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Thetha nogqirha wakho malunga nentsingiselo yeziphumo zakho zovavanyo.

I-Immunoglobulin kumchamo inokubangela ukuba:

• Ukwakhiwa okungaqhelekanga kweeproteni kwizicubu kunye namalungu (amyloidosis)
• Ileukemia
• Umhlaza wegazi ubizwa ngokuba yi-myeloma emininzi
• Ukuphazamiseka kwezintso ezifana ne-IgA nephropathy okanye i-IgM nephropathy

Abanye abantu baneemunoglobulins ezi-monoclonal, kodwa abanawo umhlaza. Oku kubizwa ngokuba yi-monoclonal gammopathy yokubaluleka okungaziwayo, okanye iMGUS.

Immunoglobulin electrophoresis - umchamo; I-Gamma globulin electrophoresis - umchamo; Umchamo immunoglobulin electrophoresis; IEP - umchamo

• Iphecana lomchamo labasetyhini
• Indoda yokuchama

IChernecky CC, iBerger BJ. Iiproteni electrophoresis - umchamo. Ku: IChernecky CC, iBerger BJ, ii-eds. Iimvavanyo zaselebhu kunye neenkqubo zokuqonda isifo. Umhla wesi-6. ISt Louis, MO: Elsevier Saunders; Ngo-2013: 920-922.

UGertz MA. Amyloidosis. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Ngomhla wama-26. IPhiladelphia, PA: Elsevier; 2020: isahl. 179.

IMcPherson RA. Iiproteni ezithile. Ku: McPherson RA, Pincus MR, ii-eds. Ukuchongwa kweKlinikhi kaHenry kunye noLawulo ngeendlela zeLebhu. Umhla we-23. ISt Louis, MO: Elsevier; Ngo-2017: isahluko 19.

URajkumar SV, iDispenzieri A. Multiple myeloma kunye nokuphazamiseka okunxulumene noko. Ku: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, ii-eds. I-Oncology yeklinikhi yase-Abeloff. Umhla wesi-6. IPhiladelphia, PA: Elsevier; 2020: isahl. 101.