I-CSF iyonke protein

I-protein ye-CSF iyonke kuvavanyo lokufumanisa isixa seprotein kwi-cerebrospinal fluid (CSF). I-CSF lulwelo olucacileyo olukulo ndawo ijikeleze intambo yomqolo kunye nengqondo.

Isampulu ye-CSF iyafuneka [1 ukuya kwi-5 yeemililitha (ml)]. Ukugqobhoza i-lumbar (impompo yomqolo) yeyona ndlela iqhelekileyo yokuqokelela le sampulu. Rhoqo, ezinye iindlela zisetyenziselwa ukuqokelela i-CSF enje:

• Ukugqobhoza amanzi
• Ukugqobhoza omoya
• Ukususwa kwe-CSF kwityhubhu esele ikwi-CSF, enje nge-shunt okanye i-ventricular drain.

Emva kokuba isampulu ithathiwe, ithunyelwa elebhu ukuvavanywa.

Unokuba nalo olu vavanyo ukunceda ukuxilonga:

• Amathumba
• Usulelo
• Ukudumba amaqela eziliqela iiseli zemithambo-luvo
• I-Vasculitis
• Igazi kulwelo lomqolo
• Multiple sclerosis (MS)

Uluhlu lweeprotheyini oluqhelekileyo luyahlukahluka kwilebhu ukuya kwilebhu, kodwa i-milligrams ezili-15 ukuya kwezingama-60 kwidesilitha nganye (mg / dL) okanye i-0.15 ukuya kwi-0.6 milligram ngeemililitha (mg / mL).

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Thetha nomboneleli wakho wezempilo malunga nentsingiselo yeziphumo zakho zovavanyo.

Imizekelo engentla ibonisa imilinganiselo eqhelekileyo yeziphumo zolu vavanyo. Ezinye iilabhoratri zisebenzisa imilinganiselo eyahlukeneyo okanye zinokuvavanya iisampulu ezahlukeneyo.

Inqanaba leprotein engaqhelekanga kwi-CSF iphakamisa ingxaki kwinkqubo ye-nervous system.

Ukunyuka kweprotein kungangumqondiso wesisu, ukopha, ukudumba kwemithambo-luvo, okanye ukwenzakala. Ukuvaleka kokuhamba kolwelo lomqolo kunokubangela ukuba kwakhiwe ngokukhawuleza iiprotein kwindawo esezantsi yomqolo.

Ukwehla kwenqanaba leprotheni kunokuthetha ukuba umzimba wakho uvelisa ngokukhawuleza ulwelo lomqolo.

• Uvavanyo lweprotheni ye-CSF

UDeluca GC, uGriggs RC. Indlela yesigulana ngesifo se-neurologic. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Ngomhla wama-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 368.

I-Euerle BD. Ukuhlanjwa komqolo kunye novavanyo lwe-cerebrospinal fluid. Ku: Roberts JR, Custalow CB, Thomsen TW, ii-eds. Iinkqubo zeKlinikhi zikaRoberts kunye neHedges kwiNyango kaXakeka kunye noKhathalelo oluQhelekileyo. Umhla wesi-7. IPhiladelphia, PA: Elsevier; I-2019: isahluko 60.

IRosenberg GA. I-edema yobuchopho kunye nokuphazamiseka kokujikeleza kolwelo lwe-cerebrospinal. Ku: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, ii-eds. I-Neurology kaBradley kwiKlinikhi yokuziqhelanisa. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2016: isahl 88.