I-CSF ye-oligoclonal banding

I-CSF ye-oligoclonal banding luvavanyo lokujonga iiproteni ezinxulumene nokudumba kwi-cerebrospinal fluid (CSF). I-CSF lulwelo olucacileyo oluhamba kwindawo ejikeleze intambo yomqolo kunye nengqondo.

Iibhanti ze-Oligoclonal ziiproteni ezibizwa ngokuba zii-immunoglobulins. Ubukho bezi proteni bubonisa ukudumba kwenkqubo ye-nervous system. Ubukho beebhendi ze-oligoclonal zisenokuthi zichaze isifo se-multiple sclerosis.

Isampulu ye-CSF iyafuneka. Ukugqobhoza i-lumbar (impompo yomqolo) yeyona ndlela iqhelekileyo yokuqokelela le sampulu.

Ezinye iindlela zokuqokelela i-CSF kunqabile ukuba zisetyenziswe, kodwa kunokucetyiswa kwezinye iimeko. Ziquka:

• Ukugqobhoza amanzi
• Ukugqobhoza omoya
• Ukususwa kwe-CSF kwityhubhu esele ikwi-CSF, enje nge-shunt okanye i-ventricular drain.

Emva kokuba isampulu ithathiwe, ithunyelwa elebhu ukuvavanywa.

Olu vavanyo lunceda ukuxhasa ukuxilongwa kwe-multiple sclerosis (MS). Nangona kunjalo, oko akuqinisekisi ukuxilongwa. Iibhanti ze-Oligoclonal kwi-CSF zinokubonwa nakwezinye izifo ezinje:

• Inkqubo ye lupus erythematosus
• Intsholongwane kaGawulayo
• Ukubetha

Ngokwesiqhelo, ibhendi enye okanye hayi kufuneka ifunyenwe kwi-CSF.

Qaphela: Uluhlu lwamaxabiso aqhelekileyo luyahluka kancinci phakathi kweelebhu ezahlukeneyo. Thetha nomboneleli wakho wezempilo malunga nentsingiselo yeziphumo zakho zovavanyo.

Imizekelo engentla ibonisa imilinganiselo eqhelekileyo yeziphumo zolu vavanyo. Ezinye iilabhoratri zisebenzisa imilinganiselo eyahlukeneyo okanye zinokuvavanya iisampulu ezahlukeneyo.

Mabini okanye nangaphezulu amabhanti afunyenwe kwi-CSF hayi egazini. Oku kunokuba ngumqondiso we-multiple sclerosis okanye okunye ukuvuvukala.

Ulwelo lweCerebrospinal-immunofixation

• I-CSF ye-oligoclonal banding-uthotho
• Ukugqobhoza iLumbar (impompo yomqolo)

UDeluca GC, uGriggs RC. Indlela yesigulana ngesifo se-neurologic. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Ngomhla wama-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 368.

IKarcher DS, iMcPherson RA. I-Cerebrospinal, synovial, i-serous body fluid, kunye nezinye iisampuli. Ku: McPherson RA, Pincus MR, ii-eds. Ukuchongwa kweKlinikhi kaHenry kunye noLawulo ngeendlela zeLebhu. Umhla we-23. ISt Louis, MO: Elsevier; Ngo-2017: isahluko 29.