Uvavanyo lwe-T3RU

Uvavanyo lwe-T3RU lilinganisela inqanaba leeproteni ezithwala i-hormone ye-thyroid egazini. Oku kunokunceda umboneleli wakho wezempilo atolike iziphumo zovavanyo lwegazi lwe-T3 kunye ne-T4.

Kuba iimvavanyo ezibizwa ngokuba luvavanyo lwegazi lwe-T4 yasimahla kunye neemvavanyo zegazi ezibopha i-globulin (TBG) ngoku, uvavanyo lwe-T3RU kunqabile ukuba lusetyenziswe kwezi ntsuku.

Isampulu yegazi iyafuneka.

Umboneleli wakho uya kukuxelela ukuba ngaba ufuna ukuyeka ukuthatha nawaphi na amayeza phambi kovavanyo olunokuchaphazela iziphumo zakho zovavanyo. SUKUYEKE ukuthatha nawaphi na amayeza ngaphandle kokuqala uthethe nomboneleli wakho.

Ezinye iziyobisi ezinokunyusa amanqanaba e-T3RU zibandakanya:

• I-Anabolic steroids
• IHeparin
• IPhenytoin
• IiSalicylates (idosi ephezulu)
• IWarfarin

Ezinye iziyobisi ezinokunciphisa amanqanaba e-T3RU zibandakanya:

• Amayeza eAntithyroid
• Iipilisi zokulawula inzala
• Clofibrate
• Estrogen
• AmaTiyazide

Ukukhulelwa nako kunokunciphisa amanqanaba e-T3RU.

Ezi meko zinokwehla amanqanaba e-TBG (jonga ngezantsi kwecandelo "Kutheni uVavanyo lwenziwa" ngakumbi nge-TBG):

• Ukugula kakhulu
• Isifo sezintso xa iprotein ilahlekile kumchamo (nephrotic syndrome)

Amanye amayeza abopha iproteni egazini anokuchaphazela iziphumo zovavanyo.

Xa kufakwa inaliti ukutsala igazi, abanye abantu baziva iintlungu eziphakathi. Abanye baziva behlaba okanye behlaba kuphela. Emva koko, kunokubakho ukubetha okanye ukukrala kancinci. Oku kuya kuhamba kungekudala.

Olu vavanyo lwenziwa ukujonga umsebenzi we-thyroid. Umsebenzi we-thyroid uxhomekeke kwisenzo samahomoni ahlukeneyo, kubandakanya i-hormone evuselela i-thyroid (TSH), i-T3 kunye ne-T4.

Olu vavanyo lunceda ukukhangela inani le-T3 i-TBG ekwaziyo ukuyibopha. I-TBG yiprotein ethwala uninzi lwe-T3 kunye ne-T4 egazini.

Umboneleli wakho unokucebisa uvavanyo lwe-T3RU ukuba uneempawu zesifo se-thyroid, kubandakanya:

• Hyperthyroidism (idyroid esebenzayo)
• I-Hypothyroidism (i-thyroid engasebenzi)
• Ukukhubazeka kwamaxesha ngamaxesha Thyrotoxic (ubuthathaka bemisipha obubangelwa ngamanqanaba aphezulu ehomoni yedlala egazini)

Amaxabiso aqhelekileyo aqala kuma-24% ukuya kuma-37%.

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye ukuvavanya iisampulu ezahlukeneyo. Thetha nomboneleli wakho malunga nentsingiselo yeziphumo zakho zovavanyo.

Amanqanaba aphezulu kunesiqhelo anokubonisa:

• Ukungaphumeleli kwezintso
• I-thyroid engasebenzi (hyperthyroidism)
• Isifo seNephrotic
• Iiproteni ukungondleki

Amanqanaba asezantsi kunesiqhelo anokubonisa:

• Hepatitis Acute (isifo sesibindi)
• Ukukhulelwa
• IHypothyroidism
• Ukusetyenziswa kwe-estrogen

Iziphumo ezingaqhelekanga zinokubangelwa yimeko yelifa lemigangatho ephezulu ye-TBG. Ngokwesiqhelo umsebenzi we-thyroid uqhelekile kubantu abakule meko.

Olu vavanyo lunokwenziwa:

• I-thyroiditis engapheliyo (ukuvuvukala okanye ukuvuvukala kwe-thyroid gland, kuquka isifo sikaHashimoto)
• I-hypothyroidism ebangelwa ziziyobisi
• Isifo samangcwaba
• Ukunyusa i-thyroiditis
• Ukukhubazeka kwamaxesha ngamaxesha
• Ityhefu

Kukho umngcipheko omncinci ochaphazelekayo ekuthatheni igazi lakho: imithambo kunye nemithambo iyahluka ngobukhulu ukusuka komnye umntu ukuya komnye kwaye ukusuka kwelinye icala lomzimba ukuya kwelinye. Ukufumana isampulu yegazi kwabanye abantu kunokuba nzima ngakumbi kunabanye.

Eminye imingcipheko enxulumene nokutsalwa kwegazi incinci, kodwa inokubandakanya:

• Ukopha kakhulu
• Ukufa isiqaqa okanye ukuziva ungenantloko
• Ukugqobhoza okuninzi ukufumana imithambo
• I-Hematoma (igazi elakhiweyo phantsi kolusu)
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

Ukuthatha i-Resin T3; Ukuthathwa kwentlaka ye-T3; Umlinganiso wehomoni ebopha ihormone

• Uvavanyo lwegazi

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UKiefer J, uMythen M, uRoizen MF, uFleisher LA. Impembelelo ye-Anesthetic yezifo ezifanayo. Ku: Gropper MA, ed. I-Anesthesia kaMiller. Umhla we-9. IPhiladelphia, PA: Elsevier; 2020: isahluko 32.

USalvatore D, uCohen R, uKopp PA, uLarsen PR. I-thyroid pathophysiology kunye novavanyo lokuqonda isifo. Ku: UMelmed S, uAuchus RJ, uGoldfine AB, uKoenig RJ, uRosen CJ, ii-eds. Incwadi ebhaliweyo kaWilliam ye-Endocrinology. Umhla we-14. IPhiladelphia, PA: Elsevier; 2020: isahl 11.

I-Weiss RE, Refetoff S. Umsebenzi wovavanyo lwe-thyroid. Ku: Jameson JL, De Groot LJ, de Kretser DM, et al, ii-eds. Endocrinology: Abantu abadala kunye nabantwana. Umhla wesi-7. IPhiladelphia, PA: Elsevier Saunders; Ngo-2016: isahluko 78.