Uvavanyo lwegazi likaRenin

Uvavanyo lwe-renin lilinganisa inqanaba le-renin egazini.

Isampulu yegazi iyafuneka.

Amayeza athile anokuchaphazela iziphumo zolu vavanyo. Umboneleli wakho wezempilo uya kukuxelela ukuba ngaba ufuna ukuyeka ukuthatha nawaphi na amayeza. SUKUYEKE nawaphi na amayeza ngaphambi kokuba uthethe nomboneleli wakho.

Amayeza anokuchaphazela imilinganiselo ye-renin ibandakanya:

• Iipilisi zokulawula inzala.
• Uxinzelelo lwegazi iziyobisi.
• Amayeza athambisa imithambo yegazi (vasodilators). Ezi zihlala zisetyenziselwa ukunyanga uxinzelelo lwegazi oluphezulu okanye ukusilela kwentliziyo.
• Iipilisi zamanzi (i-diuretics).

Umboneleli wakho unokuyalela ukuba unciphise ukutya kwakho kwesodium ngaphambi kovavanyo.

Qaphela ukuba inqanaba le-renin linokuchaphazeleka kukukhulelwa, kunye nexesha losuku kunye nokuma komzimba xa kutsalwa igazi.

Xa kufakwa inaliti ukutsala igazi, abanye abantu baziva iintlungu eziphakathi. Abanye baziva ngathi batyhafile okanye batyhafile. Emva koko, kunokubakho ukubetha okanye ukukrala kancinci. Oku kuya kuhamba kungekudala.

URenin yiprotein (enzyme) ekhutshwa ziiseli ezikhethekileyo zezintso xa unenqanaba lokuncipha kwetyuwa (isodiyam) okanye umthamo wegazi osezantsi. Rhoqo, uvavanyo lwegazi lwe-renin lwenziwa ngaxeshanye novavanyo lwegazi lwe-aldosterone ukubala i-renin kwinqanaba le-aldosterone.

Ukuba unoxinzelelo oluphezulu lwegazi, ugqirha wakho unokuyalela uvavanyo lwe-renin kunye ne-aldosterone ukunceda ukumisela unobangela woxinzelelo lwegazi oluphakamileyo. Iziphumo zovavanyo zinokukunceda ukukhokela ugqirha wakho ekukhetheni unyango oluchanekileyo.

Ukutya okuqhelekileyo kwesodium, uluhlu lwamaxabiso aqhelekileyo yi-0.6 ukuya kwi-4.3 ng / mL / ngeyure (0.6 ukuya kwi-4.3 µg / L / ngeyure). Ukutya okune-sodium ephantsi, ixabiso eliqhelekileyo li-2.9 ukuya kuma-24 ng / mL / ngeyure (2.9 ukuya ku-24 µg / L / ngeyure).

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye ukuvavanya iisampulu ezahlukeneyo. Thetha nogqirha wakho malunga nentsingiselo yeziphumo zakho zovavanyo.

Inqanaba eliphezulu le-renin linokubangelwa:

• Izibilini ze-Adrenal ezingenzi ngokwaneleyo i-hormone (i-Addison isifo okanye enye i-adrenal gland insufficiency)
• Ukopha (ukopha)
• Ukumelwa yintliziyo
• Uxinzelelo lwegazi oluphezulu olubangelwa kukucuthwa kwemithambo yegazi yezintso (uxinzelelo lwegazi)
• Ukunqongophala kwesibindi kunye nokungasebenzi kakuhle kwesibindi (cirrhosis)
• Ukuphulukana nolwelo lomzimba (ukomisa)
• Umonakalo wezintso owenza i-nephrotic syndrome
• Izidumba zezintso ezivelisa i-renin
• Ngokukhawuleza kunye noxinzelelo lwegazi oluphezulu (uxinzelelo lwegazi)

Inqanaba eliphantsi le-renin linokubangelwa:

• Amadlala eadrenal akhupha ialdosterone hormone eninzi kakhulu (hyperaldosteronism)
• Uxinzelelo lwegazi oluphezulu olunobuzaza ngetyuwa
• Unyango nge-antidiuretic hormone (ADH)
• Unyango ngamayeza e-steroid abangela ukuba umzimba ugcine ityuwa

Akukho mngcipheko ubandakanyekileyo ekuthatheni igazi lakho. Imithambo kunye nemithambo iyahluka ngobukhulu ukusuka kwisigulana esinye ukuya kwelinye nakwelinye icala lomzimba liye kwelinye. Ukuthatha igazi kwabanye abantu kunokuba nzima ngakumbi kunabanye.

Eminye imingcipheko enxulumene nokutsalwa kwegazi incinci kodwa inokubandakanya:

• Ukopha kakhulu
• Ukufa isiqaqa okanye ukuziva ungenantloko
• Ukugqobhoza okuninzi ukufumana imithambo
• I-Hematoma (igazi eliqokelela phantsi kwesikhumba)
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

Umsebenzi weplasma renin; Renin yeplasma engaqhelekanga; PRA

• Izintso - ukuhamba kwegazi kunye nomchamo
• Uvavanyo lwegazi

UGuber HA, uFarag AF. Uvavanyo lomsebenzi we-endocrine. Ku: McPherson RA, Pincus MR, ii-eds. Ukuchongwa kweKlinikhi kaHenry kunye noLawulo ngeendlela zeLebhu. Umhla we-23. ISt Louis, MO: Elsevier; Ngo-2017: isahluko 24.

Isazisi seWiner, iWingo CS. Izizathu ze-Endocrine zoxinzelelo lwegazi: aldosterone. Ku: Feehally J, Floege J, Tonelli M, Johnson RJ, ii-eds. I-Clinical Nephrology epheleleyo. Umhla wesi-6. IPhiladelphia, PA: Elsevier; I-2019: isahluko 38.