Uvavanyo lomchamo weCortisol

Uvavanyo lomchamo we-cortisol ulinganisa inqanaba le-cortisol kumchamo. ICortisol yiglucocorticoid (steroid) hormone eveliswe yidlala ye-adrenal.

ICortisol inokulinganiswa kusetyenziswa uvavanyo lwegazi okanye lwamathe.

Isampuli yomchamo weeyure ezingama-24 iyafuneka. Uya kudinga ukuqokelela umchamo wakho ngaphezulu kweeyure ezingama-24 kwisitya esinikezwe elebhu. Umboneleli wakho wezempilo uya kukuxelela ukuba ungakwenza njani oku. Landela imiyalelo ngokuchanekileyo.

Kuba imveliso yecortisol ydrenal gland inokwahluka, uvavanyo lunokufuna ukwenziwa amaxesha amathathu okanye nangaphezulu ukuze ufumane umfanekiso ochanekileyo wemveliso yecortisol.

Unokucelwa ukuba ungenzi mthambo ngamandla kusuku olungaphambi kovavanyo.

Unokuxelelwa nokuba uyeke okwethutyana amayeza anokuchaphazela uvavanyo, kubandakanya:

• Iziyobisi ezichasene nokuhlutha
• Estrogen
• Izinto ezenziwe ngabantu (zokwenziwa) zeglucocorticoids, ezinje ngehydrocortisone, prednisone kunye ne-prednisolone
• Androgens

Uvavanyo lubandakanya kuphela ukuchama okuqhelekileyo. Akukho buhlungu.

Uvavanyo lwenziwe ukukhangela ukwanda okanye ukunciphisa imveliso ye-cortisol. ICortisol yiglucocorticoid (steroid) hormone ekhutshwe kwi-adrenal gland ekuphenduleni i-adrenocorticotropic hormone (ACTH). Le yincindi yedlala ekhutshwe kwidlala lobuchopho kwingqondo. ICortisol ichaphazela iinkqubo ezahlukeneyo zomzimba. Idlala indima:

• Ukukhula kwamathambo
• Ulawulo lwexinzelelo lwegazi
• Umsebenzi we-immune system
• I-Metabolism yamafutha, iicarbohydrate, kunye neeprotein
• Umsebenzi wenkqubo yemithambo-luvo
• Impendulo yoxinzelelo

Izifo ezahlukileyo, ezinje ngeCushing syndrome kunye nesifo iAddison, zinokukhokelela kwimveliso yecortisol eninzi kakhulu okanye encinci. Ukulinganisa inqanaba lomchamo we-cortisol kunokunceda ukufumanisa imeko.

Uluhlu oluqhelekileyo yi-4 ukuya kwi-40 mcg / iiyure ezingama-24 okanye i-11 ukuya kwi-110 nmol / ngosuku.

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye zinokuvavanya iisampulu ezahlukeneyo. Thetha nomboneleli wakho malunga nentsingiselo yeziphumo zakho zovavanyo.

Inqanaba elingaphezulu kwesiqhelo linokubonisa:

• Isifo se-Cushing, apho i-pituitary gland yenza i-ACTH kakhulu ngenxa yokukhula okugqithisileyo kwe-pituitary gland okanye i-tumor kwi-pituitary gland
• I-Ectopic Cushing syndrome, apho ithumba ngaphandle kwamadlala ebuchopho okanye adrenal lenza kakhulu i-ACTH
• Uxinzelelo olukhulu
• Ithumba le-adrenal gland evelisa kakhulu i-cortisol
• Uxinzelelo olukhulu
• Iingxaki zemfuza ezinqabileyo

Inqanaba elisezantsi kuneliqhelekileyo linokubonisa:

• Isifo iAddison apho iincindi zamadlala zingavelisi ngokwaneleyo icortisol
• I-Hypopituitarism apho i-pituitary gland ingabonakali uphawu lwe-adrenal gland ukuvelisa i-cortisol eyaneleyo
• Ukuncitshiswa kwento yesiqhelo yebhinqa okanye ye-adrenal ngamayeza e-glucocorticoid kubandakanya iipilisi, iikhrimu zolusu, i-eyedrops, inhalers, inaliti edibeneyo, ichemotherapy

Akukho bungozi kolu vavanyo.

Iiyure ezingama-24 ze-uris cortisol yasimahla (UFC)

• Iphecana lomchamo labasetyhini
• Indoda yokuchama

IChernecky CC, iBerger BJ. ICortisol - umchamo. Ku: IChernecky CC, iBerger BJ, ii-eds. Iimvavanyo zaselebhu kunye neenkqubo zokuqonda isifo. Umhla wesi-6. ISt Louis, MO: Elsevier Saunders; Ngo-2013: 389-390.

Stewart PM, Newell-Price JDC. I-adrenal cortex. Ku: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, ii-eds. Incwadi ebhaliweyo kaWilliam ye-Endocrinology. Umhla we-13. IPhiladelphia, PA: Elsevier; 2016: isahluko 15.