Uvavanyo lwegazi lwe-Estradiol

Uvavanyo lwe-estradiol lilinganisela inani lehomoni ebizwa ngokuba yi-estradiol egazini. I-Estradiol yenye yeentlobo eziphambili ze-estrogens.

Isampulu yegazi iyafuneka.

Umboneleli wakho wezempilo angakuxelela ukuba uyeke okwethutyana amayeza athile anokuchaphazela iziphumo zovavanyo. Qiniseka ukuba uxelela umboneleli wakho ngawo onke amayeza owathathayo. Oku kubandakanya:

• Iipilisi zokulawula inzala
• Amayeza okubulala iintsholongwane afana ne-ampicillin okanye i-tetracycline
• ICorticosteroids
• I-DHEA (isongezelelo)
• Estrogen
• Iyeza lokulawula ukuphazamiseka kwengqondo (njengephenothiazine)
• Testosterone

SUKUYEKE ukuthatha naliphi na iyeza ngaphambi kokuba uthethe nogqirha wakho.

Xa kufakwa inaliti ukutsala igazi, abanye abantu baziva iintlungu eziphakathi. Abanye baziva behlaba okanye behlaba kuphela. Emva koko, kunokubakho ukubetha okanye ukukrala kancinci. Oku kuya kuhamba kungekudala.

Kwabasetyhini, uninzi lwe-estradiol lukhutshwa kwii-ovari nakwiidrenal gland. Kukhutshwa kwakhona nge-placenta ngexesha lokukhulelwa. I-Estradiol ikwaveliswa kwezinye izicwili zomzimba, ezinjengesikhumba, amanqatha, iiseli zamathambo, ingqondo, nesibindi. I-Estradiol idlala indima kwi:

• Ukukhula kwesibeleko (isibeleko), imibhobho yesibeleko, kunye nelungu lobufazi
• Ukukhula kwebele
• Utshintsho kumalungu angaphandle angaphandle
• Ukuhanjiswa kwamafutha omzimba
• Ukuyeka ukuya exesheni

Emadodeni, inani elincinci le-estradiol likhutshwa ikakhulu ngovavanyo. I-Estradiol inceda ukukhusela isidoda ekufeni msinyane.

Olu vavanyo lunokuyalelwa ukuba lutshekishe:

• Zisebenza kakuhle kangakanani ii-ovari, i-placenta, okanye i-adrenal gland
• Ukuba uneempawu zesisu se-ovari
• Ukuba iimpawu zomzimba wamadoda okanye wabasetyhini azikhuli ngokwesiqhelo
• Ukuba amaxesha akho ayekile (amanqanaba e-estradiol ayahluka, ngokuxhomekeke kwixesha lenyanga)

Uvavanyo lunokuyalelwa ukuba luqwalasele ukuba:

• Unyango lweHormone lusebenzela abasetyhini abasexesheni
• Umfazi uphendula kunyango lokuchuma

Uvavanyo lunokusetyenziselwa ukubeka esweni abantu abane-hypopituitarism kunye nabasetyhini kunyango oluthile lokuchuma.

Iziphumo zinokwahluka, kuxhomekeka kwisini kunye nobudala bomntu.

• Indoda - i-10 ukuya kwi-50 pg / mL (36.7 ukuya kwi-183.6 pmol / L)
• Umfazi (premenopausal) -30 ukuya ku-400 pg / mL (110 ukuya ku-1468.4 pmol / L)
• Ibhinqa (i-postmenopausal) -0-30 pg / mL (0 ukuya kwi-110 pmol / L)

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye ukuvavanya iisampulu ezahlukeneyo. Thetha nogqirha wakho malunga nentsingiselo yesiphumo sakho sovavanyo.

Ukuphazamiseka okunxulunyaniswa neziphumo ezingaqhelekanga ze-estradiol zibandakanya:

• Ukufikisa kwangethuba (kwangaphambili) kumantombazana
• Ukukhula kwamabele amakhulu ngokungaqhelekanga emadodeni (gynecomastia)
• Ukungabikho kwamaxesha kwabasetyhini (amenorrhea)
• Umsebenzi ophunguliweyo wee-ovari (i-ovarian hypofunction)
• Ingxaki yemfuza, enje ngesifo sikaKlinefelter, isifo sikaTurner
• Ukwehla ngokukhawuleza komzimba okanye ukutyeba komzimba okuncinci

Akukho mngcipheko ubandakanyekileyo ekuthatheni igazi lakho. Imithambo kunye nemithambo iyahluka ngobukhulu ukusuka komnye umntu ukuya komnye nakwelinye icala lomzimba liye kwelinye. Ukuthatha igazi kwabanye abantu kunokuba nzima ngakumbi kunabanye.

Eminye imingcipheko enxulumene nokutsalwa kwegazi incinci, kodwa inokubandakanya:

• Ukopha kakhulu
• Ukufa isiqaqa okanye ukuziva ungenantloko
• Ukugqobhoza okuninzi ukufumana imithambo
• I-Hematoma (igazi eliqokelela phantsi kwesikhumba)
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

Uvavanyo lwe-E2

UGuber HA, uFarag AF. Uvavanyo lomsebenzi we-endocrine. Ku: McPherson RA, Pincus MR, ii-eds. Ukuchongwa kweKlinikhi kaHenry kunye noLawulo ngeendlela zeLebhu. Umhla we-23. ISt Louis, MO: Elsevier; Ngo-2017: isahluko 24.

I-Haisenleder DJ, uMarshall JC. I-Gonadotropins: ukulawulwa kokudibana kunye nokugcinwa kwemfihlo. Ku: Jameson JL, De Groot LJ, de Kretser DM, et al, ii-eds. Endocrinology: Abantu abadala kunye nabantwana. Umhla wesi-7. IPhiladelphia, PA: Elsevier Saunders; I-2016: isahluko 116.