Iqondo lokuhluza leGlomerular

Izinga lokuhluza leGlomerular (GFR) luvavanyo olusetyenziselwa ukujonga ukuba izintso zisebenza kakuhle kangakanani. Ngokukodwa, iqikelela ukuba lingakanani igazi elidlula kwi-glomeruli ngomzuzu ngamnye. IGlomeruli zizicoci ezincinci kwizintso ezicoca inkunkuma egazini.

Isampulu yegazi iyafuneka.

Isampulu yegazi ithunyelwa elebhu. Apho, kuvavanywa inqanaba lokudala kwisampulu yegazi. I-Creatinine yimveliso yenkunkuma yemichiza yendalo. I-Creatine yikhemikhali eyenziwa ngumzimba ukubonelela ngamandla, ngakumbi izihlunu.

Ingcali yelebhu idibanisa inqanaba lokudala kwegazi kunye nezinye izinto ukuqikelela i-GFR yakho. Iifomula ezahlukeneyo zisetyenziselwa abantu abadala kunye nabantwana. Ifomula ibandakanya ezinye okanye zonke ezi zinto zilandelayo:

• Ubudala
• Imilinganiselo yokudala kwegazi
• Ubuhlanga
• Ukwabelana ngesondo
• Ukuphakama
• Ubunzima

Uvavanyo lokucaca kwe-creatinine, olubandakanya ukuqokelela umchamo weeyure ezingama-24, lunokubonelela ngoqikelelo lomsebenzi wezintso.

Umboneleli wakho wokhathalelo lwempilo unokukucela ukuba uyeke okwethutyana na nawaphi na amayeza anokuchaphazela iziphumo zovavanyo. Oku kubandakanya amayeza okubulala iintsholongwane kunye namayeza e-asidi esiswini.

Qiniseka ukuba uxelela umboneleli wakho ngawo onke amayeza owathathayo. Sukuyeka ukuthatha naliphi na iyeza ngaphambi kokuba uthethe nogqirha wakho.

Tshela ugqirha wakho ukuba ukhulelwe okanye ucinga ukuba unokuba. I-GFR ichaphazeleka kukukhulelwa.

Xa kufakwa inaliti ukutsala igazi, abanye abantu baziva iintlungu eziphakathi. Abanye baziva behlaba okanye behlaba kuphela. Emva koko, kunokubakho ukubetha okanye ukutyumza kancinci. Oku kuya kuhamba kungekudala.

Uvavanyo lwe-GFR luthatha amanyathelo ukuba izintso zakho zilicoca njani igazi. Ugqirha wakho angayalela olu vavanyo ukuba ngaba kukho imiqondiso yokuba izintso zakho azisebenzi kakuhle. Kungenziwa kwakhona ukubona ukuba isifo seentso siqhubele phambili kangakanani.

Uvavanyo lwe-GFR luyacetyiswa kubantu abanesifo esinganyangekiyo sezintso. Kukwacetyiswa abantu abanokuphuhlisa isifo sezintso ngenxa:

• Seswekile
• Imbali yosapho yesifo sezintso
• Izifo ezenzeka rhoqo kumchamo
• Isifo sentliziyo
• Igazi elonyukayo
• Ukuvaleka komchamo

Ngokwe-National Kidney Foundation, iziphumo eziqhelekileyo zisusela kwi-90 ukuya kwi-120 ml / min / 1.73 m². Abantu abadala baya kuba namanqanaba asezantsi kunalawo aqhelekileyo e-GFR, kuba i-GFR iyehla ngokuguga.

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye ukuvavanya iisampulu ezahlukeneyo. Thetha nogqirha wakho malunga nentsingiselo yeziphumo zakho zovavanyo.

Amanqanaba angaphantsi kwe-60 mL / min / 1.73 m² iinyanga ezi-3 nangaphezulu ziluphawu lwesifo sezintso esinganyangekiyo. I-GFR ingaphantsi kwe-15 mL / min / 1.73 m² luphawu lokusilela kwezintso kwaye lufuna unyango kwangoko.

Akukho mngcipheko ubandakanyekileyo ekuthatheni igazi lakho. Imithambo kunye nemithambo iyahluka ngobukhulu ukusuka komnye umntu ukuya komnye nakwelinye icala lomzimba liye kwelinye. Ukuthatha igazi kwabanye abantu kunokuba nzima ngakumbi kunabanye.

Eminye imingcipheko enxulumene nokutsalwa kwegazi incinci, kodwa inokubandakanya:

• Ukopha kakhulu
• Ukufa isiqaqa okanye ukuziva ungenantloko
• Ukugqobhoza okuninzi ukufumana imithambo
• I-Hematoma (igazi eliqokelela phantsi kwesikhumba)
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

GFR; Uqikelelo lwe-GFR; I-eGFR

• Uvavanyo lwe-creatinine

UKrishnan A, uLevin A. Uvavanyo lwelabhoratri yesifo sezintso: inqanaba lokuhluza i-glomerular, umchamo kunye neproteinuria. Ku: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, ii-eds. Brenner kunye noMphathi weZintso. Ngomhla we-11. IPhiladelphia, PA: Elsevier; 2020: isahluko 23.

Landry DW, Bazari H. Indlela eya kwisigulana esinesifo sezintso. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Ngomhla wama-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 106.