I-insulin Glargine (imvelaphi ye-rDNA) Inaliti

Umxholo

• Ngaphambi kokusebenzisa i-insulin glargine,
• Eli yeza linokubangela utshintsho kwiswekile yegazi lakho. Kuya kufuneka uyazi iimpawu zeswekile esezantsi kunye ephezulu yegazi kwaye wenzeni ukuba unayo le miqondiso.
• I-insulin glargine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana ezi mpawu, biza ugqirha wakho ngokukhawuleza okanye ufumane unyango olungxamisekileyo:
• I-insulin glargine overdose inokwenzeka ukuba usebenzisa i-insulin glargine kakhulu okanye ukuba usebenzisa inani elifanelekileyo le-insulin glargine kodwa utye kancinci kunesiqhelo okanye wenze umthambo ngaphezu kwesiqhelo. I-insulin glargine overdose inokubangela i-hypoglycemia. Ukuba unempawu zehypoglycemia, landela imiyalelo kagqirha wakho malunga nento ekufuneka uyenzile ukuba ukhulisa i-hypoglycemia. Ezinye iimpawu libanda:

I-insulin glargine isetyenziselwa ukunyanga isifo seswekile sokuqala (imeko apho umzimba ungayivelisi khona i-insulin kwaye ngenxa yoko ayinakho ukulawula ubungakanani beswekile esegazini). Isetyenziselwa ukunyanga abantu abanesifo seswekile sesi-2 (imeko apho umzimba ungasebenzisi i-insulin ngesiqhelo kwaye, ngenxa yoko, awunakho ukulawula isixa seswekile esegazini) abafuna i-insulin ukulawula isifo seswekile. Kubantu abanesifo seswekile sokuqala, i-insulin glargine kufuneka isetyenziswe nolunye uhlobo lwe-insulin (i-insulin emfutshane). Kubantu abanesifo seswekile sesi-2, i-insulin glargine inokusetyenziswa nolunye uhlobo lwe-insulin okanye amayeza omlomo eswekile. I-insulin glargine yinto ethatha ixesha elide, inguqulelo eyenziwe ngumntu ye-insulin yomntu. I-insulin glargine isebenza ngokutshintsha i-insulin edla ngokuveliswa ngumzimba nangokunceda ukuhambisa iswekile egazini iye kwezinye izicwili zomzimba apho isetyenziselwa khona amandla. Ikwanqanda isibindi ekuveliseni iswekile engaphezulu.

Ixesha elingaphezulu, abantu abanesifo seswekile kunye neswekile ephezulu yegazi banokuba neengxaki ezinzulu okanye ezisongela ubomi, kubandakanya isifo sentliziyo, ukubetha, iingxaki zezintso, ukonakala kwemithambo-luvo kunye neengxaki zamehlo. Sebenzisa amayeza, ukwenza utshintsho kwindlela yokuphila (umzekelo, ukutya, ukwenza umthambo, ukuyeka ukutshaya), kunye nokujonga iswekile yegazi rhoqo kunokunceda ukulawula isifo seswekile kunye nokuphucula impilo yakho. Olu nyango lunokunciphisa amathuba akho okuhlaselwa sisifo sentliziyo, ukubetha, okanye ezinye iingxaki ezinxulumene nesifo seswekile ezinje ngokusilela kwezintso, ukulimala kwentliziyo (ukubindeka, imilenze ebandayo okanye iinyawo; ukunciphisa amandla ezesondo kumadoda nabasetyhini), iingxaki zamehlo, kubandakanya notshintsho okanye ukulahleka kombono, okanye isifo seentsini. Ugqirha wakho kunye nabanye ababoneleli ngempilo bayakuthetha nawe ngeyona ndlela yokulawula isifo sakho seswekile.

I-insulin glargine iza njengesisombululo (ulwelo) ukujova ngendlela engaphantsi (phantsi kolusu). Itofwe kanye ngemini. Kufuneka usebenzise i-insulin glargine ngaxeshanye yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Sebenzisa i-insulin glargine kanye njengoko kuyalelwe. Sukuyisebenzisa ngaphezulu okanye ngaphantsi okanye uyisebenzise rhoqo kunokuyalelwa ngugqirha.

Ungaze usebenzise i-insulin glargine xa uneempawu zehypoglycemia (iswekile esezantsi yegazi) okanye ukuba ujongisisile iswekile esegazini lakho wayifumana iphantsi.

I-insulin glargine ilawula isifo seswekile kodwa ayisinyangi. Qhubeka nokusebenzisa i-insulin glargine nokuba uziva uphilile. Sukuyeka ukusebenzisa i-insulin glargine ngaphandle kokuthetha nogqirha wakho. Musa ukutshintshela kolunye uphawu okanye uhlobo lwe-insulin okanye utshintshe idosi yalo naluphi na uhlobo lwe-insulin oyisebenzisayo ngaphandle kokuthetha nogqirha wakho. Ngalo lonke ixesha jonga iilebhile ye-insulin ukuze uqiniseke ukuba ufumene uhlobo olululo lwe-insulin ekhemesti.

I-insulin glargine iza ngeengqayi kunye nakwiipeni zokuthambisa eziqulethe iikhatriji zamayeza. Qiniseka ukuba uyazi ukuba loluphi uhlobo lwesikhongozeli sakho i-insulin glargine engenayo kwaye zeziphi ezinye izinto, ezinjengeenaliti, iisirinji, okanye iipeni, kuya kufuneka utofe iyeza lakho.

Ukuba i-insulin glargine yakho iza ngeebhotile, kuya kufuneka usebenzise iisirinji ukutofa idosi yakho. Buza ugqirha wakho okanye usokhemesti akubonise indlela yokujova i-insulin glargine usebenzisa isirinji. Buza ugqirha wakho okanye usokhemesti ukuba unemibuzo malunga nohlobo lwesirinji ekufuneka uyisebenzisile.

Ukuba i-insulin glargine yakho iza ezibayeni, qiniseka ukuba uyayiqonda kwaye uyayiqonda imiyalelo yomenzi. Buza ugqirha wakho okanye usokhemisti akubonise indlela yokusebenzisa usiba. Landela umkhombandlela ngononophelo, kwaye uhlale usenza uvavanyo lokhuseleko ngaphambi kokusetyenziswa.

Ungaze uphinde usebenzise iinaliti okanye iisirinji kwaye ungaze wabelane ngeenaliti, iisirinji okanye iipeni. Ukuba usebenzisa ipeni ye-insulin, soloko ususa inaliti emva nje kokuba utofile idosi yakho. Lahla iinaliti kunye neesirinji kwisitya esinganyangekiyo. Buza ugqirha wakho okanye usokhemesti ngendlela yokusilahla isikhongozeli esinganyangekiyo.

Musa ukungxenga i-insulin glargine kwaye musa ukudibanisa i-insulin glargine nolunye uhlobo lwe-insulin.

Ungayifaka i-insulin glargine engalweni yakho ephezulu, ethangeni, okanye esiswini. Ungaze utofe i-insulin glargine emthanjeni okanye kwimisipha. Guqula (jikelezisa) indawo yenaliti kwindawo ekhethiweyo kunye nedosi nganye; zama ukunqanda ukujova indawo enye rhoqo kunakuqala kwiiveki ezi-1 ukuya kwezi-2.

Ngalo lonke ixesha jonga i-insulin glargine yakho ngaphambi kokuba uyitofa. Kufuneka icace kwaye ingenambala. Sukuyisebenzisa i-insulin glargine yakho ukuba inemibala, inamafu, okanye inezinto ezomeleleyo, okanye ukuba umhla wokuphelelwa kwebhotile udlulile.

Sukusebenzisa i-insulin glargine kwimpompo yangaphandle ye-insulin.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa i-insulin glargine,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-insulin (Humulin, Novolin, abanye), naziphi na izithako ze-insulin glargine, okanye amanye amayeza. Buza usokhemesti wakho okanye ujonge ulwazi lomenzi wesigulana uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye neemveliso zamayeza owathathayo. Qiniseka ukuba ukhankanya nayiphi na kwezi zilandelayo: albuterol (Accuneb, Proair, Proventil, abanye); amayeza kagqirha kunye nonprescription aqukethe utywala; i-angiotensin-converting enzyme inhibitors (i-ACE inhibitors) enjenge-benazepril (Lotensin, eLotrel), captopril, enalapril (Epaned, Vasotec, in Vaseretic), fosinopril, lisinopril (ePrinzide, eZestoretic), moexipril, perindopalia quinapril (Accupril, in Accuretic, in Quinaretic), ramipril (Altace), kunye netrandolapril (Mavik, eTarka); ii-angiotensin receptor blockers (ARBs) ezinje nge-azilsartan (Edarbi, e-Edarbyclor), candesartan (Atacand, e-Atacand HCT), eprosartan (Teveten), irbesartan (Avapro, eAvalide), losartan (Cozaar, e-Hyzaar), telmisartan Micard eMicardis HCT, eTwynsta), valsartan (Diovan, eDiovan HCT, e-Exforge); ii-antipsychotic ezifana ne-clozapine (Clozaril, Fazaclo, Versacloz) kunye ne-olanzapine (iZyprexa, kwi-Symbyax); ii-beta-blockers ezinjenge-atenolol (Tenormin, kwi-Tenoretic), labetalol (Trandate), metoprolol (Lopressor, Toprol XL, eDutoprol), nadolol (Corgard, eCorzide), kunye nepropranolol (Hemangeol, Inderal LA, Innopran XL); amayeza athile okwehlisa i-cholesterol njenge-fenofibrate (Antara, Lipofen, Triglide), gemfibrozil (Lopid), kunye ne-niacin (Niacor, Niaspan); clonidine (Catapres, Catapres-TTS, Kapvay, eClorpres, abanye); idanazol; iDisopyramide (iNorpace); umchamo ('iipilisi zamanzi'); ii-estrogens; i-fluoxetine (Prozac, Sarafem, Selfemra, kwi-Symbyax); iglucagon; i-guanethidine (ayifumaneki e-U.S.); I-HIV protease inhibitors kubandakanya atazanavir (Reyataz), indinavir (Crixivan), lopinavir (eKaletra), nelfinavir (Viracept), ritonavir (Norvir, e Kaletra, e Viekira Pak), kunye ne saquinavir (Invirase); Unyango lwehormone (iipilisi zokulawula ukuzalwa, iipatches, iiringi, inaliti, okanye izinto zokufaka); isoniazid (Laniazid, eRifamate, eRifater); lithium (Lithobid); amayeza umbefu kunye nemikhuhlane; amayeza okugula ngengqondo kunye nesicaphucaphu; I-monoamine oxidase (MAO) inhibitors kubandakanya isocarboxazid (Marplan), linezolid (Zyvox), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), kunye ne-tranylcypromine (iParnate); i-octreotide (iSandostatin); izinto zokucwangcisa ngomlomo (iipilisi zolawulo lokuzalwa); amayeza omlomo weswekile afana nepioglitazone (Actos, eActoplus Met, eOseni, abanye) kunye neRosiglitazone (Avandia); i-steroids yomlomo efana ne-dexamethasone, i-methylprednisolone (iMedrol), kunye ne-prednisone (iRayos); ipentamidine (NebuPent, Pentam); ipentoxifylline (Pentoxil); pramlintide (Symlin); ipropoxyphene (ayifumaneki e-U.S.); gqithisela; iintlungu ze-salicylate ziyancipha njenge-aspirin, i-choline magnesium trisalicylate, i-choline salicylate, i-diflunisal, i-magnesium salicylate (Doan's, abanye), kunye ne-salsalate; somatropin (Genotropin, Humatrope, Nutropin, Serostim, nabanye); isulfa antibiotics; iterbutaline; kunye namayeza e-thyroid. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe wanomonakalo wemithambo-luvo obangelwe sisifo seswekile, ukusilela kwentliziyo, amanqanaba asezantsi egazi potassium; okanye ezinye iimeko zonyango, kubandakanya intliziyo, isibindi okanye isifo sezintso.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa usebenzisa i-insulin glargine, tsalela umnxeba ugqirha wakho.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba usebenzisa i-insulin glargine.
• utywala kunokubangela utshintsho iswekile yegazi. Buza ugqirha wakho malunga nokusetyenziswa okukhuselekileyo kotywala ngelixa usebenzisa i-insulin glargine.
• Buza ugqirha wakho ukuba wenzeni ukuba uyagula, unengxaki yoxinzelelo engaqhelekanga, okanye utshintshe indlela otya ngayo, umthambo, okanye inkqubo yokwenza umsebenzi. Olu tshintsho lunokuchaphazela iswekile yegazi kunye nenani le-insulin oza kuyidinga.
• buza ugqirha wakho ukuba kufuneka ujonge kangaphi iswekile yegazi lakho. Yazi ukuba i-hypoglycemia inokuchaphazela amandla akho okwenza imisebenzi enjengokuqhuba kwaye ubuze ugqirha wakho ukuba ufuna ukujonga iswekile yegazi ngaphambi kokuqhuba okanye ukusebenzisa oomatshini.

Qiniseka ukuba ulandela yonke imithambo kunye nezincomo zokutya ezenziwe ngugqirha wakho okanye ugqirha otya ukutya. Kubalulekile ukutya ukutya okusempilweni kunye nokutya malunga nokulingana kweentlobo ezifanayo zokutya malunga namaxesha afanayo suku ngalunye. Ukutsiba okanye ukulibazisa ukutya okanye ukutshintsha inani okanye uhlobo lokutya okutyayo kunokubangela iingxaki kulawulo lweswekile yegazi.

Ngaphambi kokuba uqale ukusebenzisa i-insulin glargine, buza ugqirha wakho ukuba wenzeni ukuba uyalibala ukusebenzisa idosi okanye ukuba ngempazamo usebenzise idosi eyongezelelweyo. Bhala le miyalelo phantsi ukuze ubhekise kubo kamva.

Eli yeza linokubangela utshintsho kwiswekile yegazi lakho. Kuya kufuneka uyazi iimpawu zeswekile esezantsi kunye ephezulu yegazi kwaye wenzeni ukuba unayo le miqondiso.

I-insulin glargine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ubomvu, ukudumba, iintlungu, okanye ukurhawuzelela kwindawo yenaliti
• Utshintsho kwindlela oziva ngayo ulusu lwakho, ukuqina kolusu (ukwakha amanqatha), okanye ukudakumba okuncinci kulusu (ukonakala kwamafutha)
• umkhuhlane, ukukhohlela, umqala obuhlungu, okanye ezinye iimpawu zosulelo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana ezi mpawu, biza ugqirha wakho ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• irhashalala, urticaria, okanye ukurhawuzelela umzimba wonke
• ukuvutha
• ubunzima bokuphefumla okanye ukugwinya
• ukubetha ngokukhawuleza
• ukubila
• ukudumba kwamehlo, ubuso, imilebe, ulwimi, okanye umqala
• ukudinwa
• ubuthathaka
• izihlunu zemithambo
• ukubetha kwentliziyo okungaqhelekanga
• ukukhawuleza ukutyeba
• ukudumba kwamaqatha okanye iinyawo
• ukuqhawukelwa ngumphefumlo
• utshintsho lombono

I-insulin glargine inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa usebenzisa eli yeza.

Gcina eli yeza kwisikhongozeli lingena lingenakufikelela ebantwaneni. Gcina iibhotile ze-insulin ezingavulwanga kunye neepeni kwifriji. Ungaze uvumele i-insulin glargine ibe ngumkhenkce; Sukusebenzisa i-insulin glargine efriziwe ngumkhenkce kwaye inyibilikisiwe. I-insulin glargine engavulelwanga inokugcinwa kude kube ngumhla oboniswe kwileyibhile yenkampani.

Ukuba ifriji ayifumaneki (umzekelo, xa useholideyini), gcina iibhotile okanye iipeni kubushushu begumbi kwaye kude nelanga ngqo kunye nobushushu obukhulu. Iibhotile okanye iipeni ezingafakwanga efrijini zinokusetyenziswa kwiintsuku ezingama-28; emva kwelo xesha kufuneka zilahlwe. Iibhotile ezivuliweyo zingagcinwa kangangeentsuku ezingama-28 kubushushu begumbi okanye kwifriji. Iipeni ezivuliweyo mazigcinwe kubushushu begumbi kwaye zinokusetyenziselwa ukuya kuthi ga kwiintsuku ezingama-28 emva kokusetyenziswa kokuqala. Lahla nayiphi na i-insulin ethe yafumana ubushushu obugqithisileyo okanye ukubanda.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

I-insulin glargine overdose inokwenzeka ukuba usebenzisa i-insulin glargine kakhulu okanye ukuba usebenzisa inani elifanelekileyo le-insulin glargine kodwa utye kancinci kunesiqhelo okanye wenze umthambo ngaphezu kwesiqhelo. I-insulin glargine overdose inokubangela i-hypoglycemia. Ukuba unempawu zehypoglycemia, landela imiyalelo kagqirha wakho malunga nento ekufuneka uyenzile ukuba ukhulisa i-hypoglycemia. Ezinye iimpawu libanda:

• ukulahleka kwengqondo
• ukuxhuzula

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Iswekile yegazi lakho kunye ne-hemoglobin eglycosylated (HbA1c) kufuneka ihlolwe rhoqo ukumisela impendulo yakho kwi-insulin glargine. Ugqirha wakho uya kukuxelela nendlela yokujonga impendulo yakho kolu nyango ngokulinganisa amanqanaba eswekile yegazi lakho ekhaya. Landela le miyalelo ngononophelo.

Kufuneka usoloko unxibe isacholo esichaza isifo seswekile ukuze uqiniseke ukuba ufumana unyango olufanelekileyo ngexesha likaxakeka.

Musa ukuvumela omnye umntu asebenzise amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• I-Basaglar^®
• ILantus^®
• Toujeo^®
• Soliqua^® (njengemveliso yokudibanisa equlethe i-Insulin Glargine kunye neLixisenatide),